en.unionpedia.org

ELQ-300, the Glossary

ELQ-300 is an experimental antimalarial medication.^[1]

Antimalarial medication

Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women. ELQ-300 and antimalarial medication are Antimalarial agents.

See ELQ-300 and Antimalarial medication

Apicomplexan life cycle

Apicomplexans, a group of intracellular parasites, have life cycle stages that allow them to survive the wide variety of environments they are exposed to during their complex life cycle.

See ELQ-300 and Apicomplexan life cycle

Bioavailability

In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation.

See ELQ-300 and Bioavailability

Coenzyme Q – cytochrome c reductase

The coenzyme Q: cytochrome c – oxidoreductase, sometimes called the cytochrome bc1 complex, and at other times complex III, is the third complex in the electron transport chain, playing a critical role in biochemical generation of ATP (oxidative phosphorylation).

See ELQ-300 and Coenzyme Q – cytochrome c reductase

Electron transport chain

An electron transport chain (ETC) is a series of protein complexes and other molecules which transfer electrons from electron donors to electron acceptors via redox reactions (both reduction and oxidation occurring simultaneously) and couples this electron transfer with the transfer of protons (H+ ions) across a membrane.

See ELQ-300 and Electron transport chain

Fungicide

Fungicides are pesticides used to kill parasitic fungi or their spores.

See ELQ-300 and Fungicide

Malaria

Malaria is a mosquito-borne infectious disease that affects vertebrates.

See ELQ-300 and Malaria

National Institutes of Health

The National Institutes of Health, commonly referred to as NIH, is the primary agency of the United States government responsible for biomedical and public health research.

See ELQ-300 and National Institutes of Health

Plasmodium falciparum

Plasmodium falciparum is a unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that causes malaria in humans.

See ELQ-300 and Plasmodium falciparum

Plasmodium vivax

Plasmodium vivax is a protozoal parasite and a human pathogen.

See ELQ-300 and Plasmodium vivax

Preclinical development

In drug development, preclinical development (also termed preclinical studies or nonclinical studies) is a stage of research that begins before clinical trials (testing in humans) and during which important feasibility, iterative testing and drug safety data are collected, typically in laboratory animals.

See ELQ-300 and Preclinical development