Estradiol 17beta-dehydrogenase, the Glossary
In enzymology, an estradiol 17beta-dehydrogenase is an enzyme that catalyzes the chemical reaction The 3 substrates of this enzyme are estradiol-17beta, NAD+, and NADP+, whereas its 4 products are estrone, NADH, NADPH, and H+.[1]
Table of Contents
16 relations: Androgen, Catalysis, Chemical reaction, Enzyme, Estradiol, Estrogen, Estrone, Hydrogen ion, List of enzymes, Nicotinamide adenine dinucleotide, Nicotinamide adenine dinucleotide phosphate, Oxidoreductase, Product (chemistry), Protein Data Bank, Protein tertiary structure, Substrate (chemistry).
- Steroid hormone biosynthesis
Androgen
An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.
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Catalysis
Catalysis is the increase in rate of a chemical reaction due to an added substance known as a catalyst.
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Chemical reaction
A chemical reaction is a process that leads to the chemical transformation of one set of chemical substances to another.
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Enzyme
Enzymes are proteins that act as biological catalysts by accelerating chemical reactions.
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Estradiol
Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone.
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Estrogen
Estrogen (oestrogen; see spelling differences) is a category of sex hormone responsible for the development and regulation of the female reproductive system and secondary sex characteristics.
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Estrone
Estrone (E1), also spelled oestrone, is a steroid, a weak estrogen, and a minor female sex hormone.
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Hydrogen ion
A hydrogen ion is created when a hydrogen atom loses an electron.
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List of enzymes
Enzymes are listed here by their classification in the International Union of Biochemistry and Molecular Biology's Enzyme Commission (EC) numbering system.
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Nicotinamide adenine dinucleotide
Nicotinamide adenine dinucleotide (NAD) is a coenzyme central to metabolism.
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Nicotinamide adenine dinucleotide phosphate
Nicotinamide adenine dinucleotide phosphate, abbreviated NADP or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NADPH as a reducing agent ('hydrogen source').
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Oxidoreductase
In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule, the reductant, also called the electron donor, to another, the oxidant, also called the electron acceptor.
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Product (chemistry)
Products are the species formed from chemical reactions.
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Protein Data Bank
The Protein Data Bank (PDB) is a database for the three-dimensional structural data of large biological molecules such as proteins and nucleic acids, which is overseen by the Worldwide Protein Data Bank (wwPDB).
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Protein tertiary structure
Protein tertiary structure is the three-dimensional shape of a protein.
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Substrate (chemistry)
In chemistry, the term substrate is highly context-dependent.
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See also
Steroid hormone biosynthesis
- 17β-Hydroxysteroid dehydrogenase
- 21-Hydroxylase
- 3β-Hydroxysteroid dehydrogenase
- 5α-Reductase
- CYP17A1
- Cholesterol side-chain cleavage enzyme
- Cytochrome P450 reductase
- Estradiol 17beta-dehydrogenase
- Ferredoxin
- Lanosterol synthase
- Squalene
- Steroid 11β-hydroxylase
- Steroidogenic acute regulatory protein
- Testosterone 17b-dehydrogenase (NADP+)
References
[1] https://en.wikipedia.org/wiki/Estradiol_17beta-dehydrogenase
Also known as 17beta-estradiol:NAD(P)+ 17-oxidoreductase, EC 1.1.1.62, Estradiol 17b-dehydrogenase.