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Etomidate, the Glossary

Etomidate (USAN, INN, BAN; marketed as Amidate) is a short-acting intravenous anaesthetic agent used for the induction of general anaesthesia and sedation for short procedures such as reduction of dislocated joints, tracheal intubation, cardioversion and electroconvulsive therapy.^[1]

57 relations: ACTH stimulation test, Adrenal gland, Allosteric modulator, Benzodiazepine, Bile duct, Binding site, Biosynthesis, Blood plasma, British Approved Name, Cahn–Ingold–Prelog priority rules, Capital punishment, Cardioversion, Corticosteroid, Cushing's syndrome, Diário Oficial da União, Electroconvulsive therapy, Enantiomer, Enzyme, Ester, Esterase, Exponential decay, GABAA receptor, General anaesthesia, Hydrocortisone, Hydrolysis, Intensive care unit, International nonproprietary name, Intravenous therapy, Janssen Pharmaceuticals, Lipid emulsion, Liver, Mark Asay, Midazolam, Montreal Neurological Institute and Hospital, Opioid, Oral administration, Potassium acetate, Potassium chloride, Procedural sedation and analgesia, Propofol, Propylene glycol, Protein subunit, Racemic mixture, Rapid sequence induction, Receptor (biochemistry), Retrospective cohort study, Rocuronium bromide, Route of administration, Sedation, Sedative, ... Expand index (7 more) »
11β-Hydroxylase inhibitors
CYP17A1 inhibitors
Chemical substances for emergency medicine
Cholesterol side-chain cleavage enzyme inhibitors
Lethal injection components

ACTH stimulation test

The ACTH test (also called the cosyntropin, tetracosactide, or Synacthen test) is a medical test usually requested and interpreted by endocrinologists to assess the functioning of the adrenal glands' stress response by measuring the adrenal response to adrenocorticotropic hormone (ACTH; corticotropin) or another corticotropic agent such as tetracosactide (cosyntropin, tetracosactrin; Synacthen) or alsactide (Synchrodyn).

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Adrenal gland

The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol.

See Etomidate and Adrenal gland

Allosteric modulator

In pharmacology and biochemistry, allosteric modulators are a group of substances that bind to a receptor to change that receptor's response to stimuli.

See Etomidate and Allosteric modulator

Benzodiazepine

Benzodiazepines (BZD, BDZ, BZs), colloquially called "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.

See Etomidate and Benzodiazepine

Bile duct

A bile duct is any of a number of long tube-like structures that carry bile, and is present in most vertebrates.

See Etomidate and Bile duct

Binding site

In biochemistry and molecular biology, a binding site is a region on a macromolecule such as a protein that binds to another molecule with specificity.

See Etomidate and Binding site

Biosynthesis

Biosynthesis, i.e., chemical synthesis occuring in biological contexts, is a term most often referring to multi-step, enzyme-catalyzed processes where chemical substances absorbed as nutrients (or previously converted through biosynthesis) serve as enzyme substrates, with conversion by the living organism either into simpler or more complex products.

See Etomidate and Biosynthesis

Blood plasma

Blood plasma is a light amber-colored liquid component of blood in which blood cells are absent, but which contains proteins and other constituents of whole blood in suspension.

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British Approved Name

A British Approved Name (BAN) is the official, non-proprietary, or generic name given to a pharmaceutical substance, as defined in the British Pharmacopoeia (BP).

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Cahn–Ingold–Prelog priority rules

In organic chemistry, the Cahn–Ingold–Prelog (CIP) sequence rules (also the CIP priority convention; named after Robert Sidney Cahn, Christopher Kelk Ingold, and Vladimir Prelog) are a standard process to completely and unequivocally name a stereoisomer of a molecule.

See Etomidate and Cahn–Ingold–Prelog priority rules

Capital punishment

Capital punishment, also known as the death penalty and formerly called judicial homicide, is the state-sanctioned killing of a person as punishment for actual or supposed misconduct.

See Etomidate and Capital punishment

Cardioversion

Cardioversion is a medical procedure by which an abnormally fast heart rate (tachycardia) or other cardiac arrhythmia is converted to a normal rhythm using electricity or drugs.

See Etomidate and Cardioversion

Corticosteroid

Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.

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Cushing's syndrome

Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol.

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Diário Oficial da União

The Diário Oficial da União (literally Official Diary of the Union), abbreviated DOU, is the official journal of the federal government of Brazil.

See Etomidate and Diário Oficial da União

Electroconvulsive therapy

Electroconvulsive therapy (ECT) or electroshock therapy (EST) is a psychiatric treatment where a generalized seizure (without muscular convulsions) is electrically induced to manage refractory mental disorders.

See Etomidate and Electroconvulsive therapy

Enantiomer

In chemistry, an enantiomer (/ɪˈnænti.əmər, ɛ-, -oʊ-/ ''ih-NAN-tee-ə-mər''; from Ancient Greek ἐναντίος (enantíos) 'opposite', and μέρος (méros) 'part') – also called optical isomer, antipode, or optical antipode – is one of two stereoisomers that are nonsuperposable onto their own mirror image.

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Enzyme

Enzymes are proteins that act as biological catalysts by accelerating chemical reactions.

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Ester

In chemistry, an ester is a functional group derived from an acid (organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group of that acid is replaced by an organyl group.

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Esterase

In biochemistry, an esterase is a class of enzyme that splits esters into an acid and an alcohol in a chemical reaction with water called hydrolysis (and as such, it is a type of hydrolase).

See Etomidate and Esterase

Exponential decay

A quantity is subject to exponential decay if it decreases at a rate proportional to its current value.

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GABAA receptor

The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.

See Etomidate and GABAA receptor

General anaesthesia

General anaesthesia (UK) or general anesthesia (US) is a method of medically inducing loss of consciousness that renders a patient unarousable even with painful stimuli.

See Etomidate and General anaesthesia

Hydrocortisone

Hydrocortisone is the name for the hormone cortisol when supplied as a medication.

See Etomidate and Hydrocortisone

Hydrolysis

Hydrolysis is any chemical reaction in which a molecule of water breaks one or more chemical bonds.

See Etomidate and Hydrolysis

Intensive care unit

An intensive care unit (ICU), also known as an intensive therapy unit or intensive treatment unit (ITU) or critical care unit (CCU), is a special department of a hospital or health care facility that provides intensive care medicine.

See Etomidate and Intensive care unit

International nonproprietary name

An international nonproprietary name (INN) is an official generic and nonproprietary name given to a pharmaceutical drug or an active ingredient.

See Etomidate and International nonproprietary name

Intravenous therapy

Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.

See Etomidate and Intravenous therapy

Janssen Pharmaceuticals

Johnson & Johnson Innovative Medicine (formerly Janssen Pharmaceuticals) is a pharmaceutical company headquartered in Beerse, Belgium, and wholly-owned by Johnson & Johnson. Etomidate and Janssen Pharmaceuticals are Janssen Pharmaceutica.

See Etomidate and Janssen Pharmaceuticals

Lipid emulsion

Lipid emulsion or fat emulsion refers to an emulsion of fat for human intravenous use, to administer nutrients to critically-ill patients that cannot consume food.

See Etomidate and Lipid emulsion

Liver

The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.

See Etomidate and Liver

Mark Asay

Mark James Asay (March 12, 1964 – August 24, 2017) was an American spree killer who was executed by the state of Florida for the 1987 racially motivated murders of two men in Jacksonville, Florida.

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Midazolam

Midazolam, sold under the brand name Versed among others, is a benzodiazepine medication used for anesthesia, premedication before surgical anesthesia, and procedural sedation, and to treat severe agitation. Etomidate and Midazolam are chemical substances for emergency medicine, GABAA receptor positive allosteric modulators and Lethal injection components.

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Montreal Neurological Institute and Hospital

The Montreal Neurological Institute-Hospital (MNI), also known as Montreal Neuro or The Neuro, is a research and medical centre dedicated to neuroscience, training and clinical care, located in the city's downtown core of Montreal, Quebec, Canada.

See Etomidate and Montreal Neurological Institute and Hospital

Opioid

Opioids are a class of drugs that derive from, or mimic, natural substances found in the opium poppy plant.

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Oral administration

| name.

See Etomidate and Oral administration

Potassium acetate

Potassium acetate (also called potassium ethanoate), (CH3COOK) is the potassium salt of acetic acid. Etomidate and potassium acetate are Lethal injection components.

See Etomidate and Potassium acetate

Potassium chloride

Potassium chloride (KCl, or potassium salt) is a metal halide salt composed of potassium and chlorine. Etomidate and potassium chloride are Lethal injection components.

See Etomidate and Potassium chloride

Procedural sedation and analgesia

Procedural sedation and analgesia (PSA) is a technique in which a sedating/dissociative medication is given, usually along with an analgesic medication, in order to perform non-surgical procedures on a patient.

See Etomidate and Procedural sedation and analgesia

Propofol

Propofol is the active component of an intravenous anesthetic formulation used for induction and maintenance of general anesthesia. Etomidate and Propofol are chemical substances for emergency medicine, GABAA receptor positive allosteric modulators, general anesthetics and Glycine receptor agonists.

See Etomidate and Propofol

Propylene glycol

Propylene glycol (IUPAC name: propane-1,2-diol) is a viscous, colorless liquid.

See Etomidate and Propylene glycol

Protein subunit

In structural biology, a protein subunit is a polypeptide chain or single protein molecule that assembles (or "coassembles") with others to form a protein complex.

See Etomidate and Protein subunit

Racemic mixture

In chemistry, a racemic mixture or racemate is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule or salt.

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Rapid sequence induction

In anaesthesia and advanced airway management, rapid sequence induction (RSI) – also referred to as rapid sequence intubation or as rapid sequence induction and intubation (RSII) or as crash induction – is a special process for endotracheal intubation that is used where the patient is at a high risk of pulmonary aspiration.

See Etomidate and Rapid sequence induction

Receptor (biochemistry)

In biochemistry and pharmacology, receptors are chemical structures, composed of protein, that receive and transduce signals that may be integrated into biological systems.

See Etomidate and Receptor (biochemistry)

Retrospective cohort study

A retrospective cohort study, also called a historic cohort study, is a longitudinal cohort study used in medical and psychological research.

See Etomidate and Retrospective cohort study

Rocuronium bromide

Rocuronium bromide (brand names Zemuron, Esmeron) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate tracheal intubation by providing skeletal muscle relaxation, most commonly required for surgery or mechanical ventilation. Etomidate and Rocuronium bromide are chemical substances for emergency medicine and Lethal injection components.

See Etomidate and Rocuronium bromide

Route of administration

In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body.

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Sedation

Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure.

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Sedative

A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement.

See Etomidate and Sedative

Steroid 11β-hydroxylase

Steroid 11β-hydroxylase, also known as steroid 11β-monooxygenase, is a steroid hydroxylase found in the zona glomerulosa and zona fasciculata of the adrenal cortex.

See Etomidate and Steroid 11β-hydroxylase

Steroid hormone

A steroid hormone is a steroid that acts as a hormone.

See Etomidate and Steroid hormone

Steroidogenesis inhibitor

A steroidogenesis inhibitor, also known as a steroid biosynthesis inhibitor, is a type of drug which inhibits one or more of the enzymes that are involved in the process of steroidogenesis, the biosynthesis of endogenous steroids and steroid hormones.

See Etomidate and Steroidogenesis inhibitor

References

[1] https://en.wikipedia.org/wiki/Etomidate

Also known as ATC code N01AX07, ATCvet code QN01AX07, Amidate, Hypnomidate, Tomvi.

, Steroid 11β-hydroxylase, Steroid hormone, Steroidogenesis inhibitor, Tracheal intubation, Transmembrane domain, Traumatic brain injury, United States Adopted Name.

Etomidate, the Glossary

Table of Contents

See also

11β-Hydroxylase inhibitors

CYP17A1 inhibitors

Chemical substances for emergency medicine

Cholesterol side-chain cleavage enzyme inhibitors

Lethal injection components

References