Exon junction complex, the Glossary
An exon junction complex (EJC) is a protein complex which forms on a pre-messenger RNA strand at the junction of two exons which have been joined together during RNA splicing.[1]
Table of Contents
51 relations: Adenosine triphosphate, ALYREF, Amino acid, Arginine, Asparagine, ATPase, BAT1, Beta sheet, CDKN2B, Chromatin, Coactivator (genetics), Crystallization, Cytoplasm, DEAD box, DEK (gene), EIF4A3, Eukaryote, Eukaryotic translation termination factor 1, Exon, GSPT1, Helicase, Initiation factor, MAGOH, Messenger RNA, MRNA surveillance, N6-Methyladenosine, Nonsense mutation, Nonsense-mediated decay, Nuclear pore, Nucleoprotein, Nucleotide, NXF1, NXT1, Phosphorylation, PI3K/AKT/mTOR pathway, Primary transcript, Protein, Protein complex, RBM8A, Ribosome, RNA, RNA splicing, RNPS1, Salt bridge (protein and supramolecular), SMG1, SRRM1, Stop codon, Translation (biology), UPF1, UPF2, ... Expand index (1 more) »
Adenosine triphosphate
Adenosine triphosphate (ATP) is a nucleotide that provides energy to drive and support many processes in living cells, such as muscle contraction, nerve impulse propagation, and chemical synthesis.
See Exon junction complex and Adenosine triphosphate
ALYREF
Aly/REF export factor, also known as THO complex subunit 4 is a protein that in humans is encoded by the ALYREF gene.
See Exon junction complex and ALYREF
Amino acid
Amino acids are organic compounds that contain both amino and carboxylic acid functional groups.
See Exon junction complex and Amino acid
Arginine
Arginine is the amino acid with the formula (H2N)(HN)CN(H)(CH2)3CH(NH2)CO2H.
See Exon junction complex and Arginine
Asparagine
Asparagine (symbol Asn or N) is an α-amino acid that is used in the biosynthesis of proteins.
See Exon junction complex and Asparagine
ATPase
ATPases (Adenosine 5'-TriPhosphatase, adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion or the inverse reaction.
See Exon junction complex and ATPase
BAT1
Spliceosome RNA helicase BAT1 is an enzyme that in humans is encoded by the BAT1 gene.
See Exon junction complex and BAT1
Beta sheet
The beta sheet (β-sheet, also β-pleated sheet) is a common motif of the regular protein secondary structure.
See Exon junction complex and Beta sheet
CDKN2B
Cyclin-dependent kinase 4 inhibitor B also known as multiple tumor suppressor 2 (MTS-2) or p15INK4b is a protein that is encoded by the CDKN2B gene in humans.
See Exon junction complex and CDKN2B
Chromatin
Chromatin is a complex of DNA and protein found in eukaryotic cells.
See Exon junction complex and Chromatin
Coactivator (genetics)
A coactivator is a type of transcriptional coregulator that binds to an activator (a transcription factor) to increase the rate of transcription of a gene or set of genes.
See Exon junction complex and Coactivator (genetics)
Crystallization
Crystallization is the process by which solids form, where the atoms or molecules are highly organized into a structure known as a crystal.
See Exon junction complex and Crystallization
Cytoplasm
In cell biology, the cytoplasm describes all material within a eukaryotic cell, enclosed by the cell membrane, except for the cell nucleus.
See Exon junction complex and Cytoplasm
DEAD box
DEAD box proteins are involved in an assortment of metabolic processes that typically involve RNAs, but in some cases also other nucleic acids.
See Exon junction complex and DEAD box
DEK (gene)
The human DEK gene encodes the DEK protein.
See Exon junction complex and DEK (gene)
EIF4A3
Eukaryotic initiation factor 4A-III is a protein that in humans is encoded by the EIF4A3 gene.
See Exon junction complex and EIF4A3
Eukaryote
The eukaryotes constitute the domain of Eukarya or Eukaryota, organisms whose cells have a membrane-bound nucleus.
See Exon junction complex and Eukaryote
Eukaryotic translation termination factor 1
Eukaryotic translation termination factor 1 (eRF1), also referred to as TB3-1 or SUP45L1, is a protein that is encoded by the ERF1 gene.
See Exon junction complex and Eukaryotic translation termination factor 1
Exon
An exon is any part of a gene that will form a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing. Exon junction complex and exon are Spliceosome.
See Exon junction complex and Exon
GSPT1
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A is an enzyme that in humans is encoded by the GSPT1 gene.
See Exon junction complex and GSPT1
Helicase
Helicases are a class of enzymes thought to be vital to all organisms.
See Exon junction complex and Helicase
Initiation factor
In molecular biology, initiation factors are proteins that bind to the small subunit of the ribosome during the initiation of translation, a part of protein biosynthesis.
See Exon junction complex and Initiation factor
MAGOH
Protein mago nashi homolog is a protein that in humans is encoded by the MAGOH gene.
See Exon junction complex and MAGOH
Messenger RNA
In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of synthesizing a protein. Exon junction complex and messenger RNA are RNA and Spliceosome.
See Exon junction complex and Messenger RNA
MRNA surveillance
mRNA surveillance mechanisms are pathways utilized by organisms to ensure fidelity and quality of messenger RNA (mRNA) molecules. Exon junction complex and MRNA surveillance are RNA.
See Exon junction complex and MRNA surveillance
N6-Methyladenosine
N6-Methyladenosine (m6A) was originally identified and partially characterised in the 1970s, and is an abundant modification in mRNA and DNA.
See Exon junction complex and N6-Methyladenosine
Nonsense mutation
In genetics, a nonsense mutation is a point mutation in a sequence of DNA that results in a nonsense codon, or a premature stop codon in the transcribed mRNA, and leads to a truncated, incomplete, and possibly nonfunctional protein product.
See Exon junction complex and Nonsense mutation
Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that exists in all eukaryotes.
See Exon junction complex and Nonsense-mediated decay
Nuclear pore
A nuclear pore is a channel as part of the nuclear pore complex (NPC), a large protein complex found in the nuclear envelope of eukaryotic cells.
See Exon junction complex and Nuclear pore
Nucleoprotein
Nucleoproteins are proteins conjugated with nucleic acids (either DNA or RNA).
See Exon junction complex and Nucleoprotein
Nucleotide
Nucleotides are organic molecules composed of a nitrogenous base, a pentose sugar and a phosphate.
See Exon junction complex and Nucleotide
NXF1
Nuclear RNA export factor 1, also known as NXF1 or TAP, is a protein which in humans is encoded by the NXF1 gene.
See Exon junction complex and NXF1
NXT1
NTF2-related export protein 1 is a protein that in humans is encoded by the NXT1 gene.
See Exon junction complex and NXT1
Phosphorylation
In biochemistry, phosphorylation is the attachment of a phosphate group to a molecule or an ion.
See Exon junction complex and Phosphorylation
PI3K/AKT/mTOR pathway
The PI3K/AKT/mTOR pathway is an intracellular signaling pathway important in regulating the cell cycle.
See Exon junction complex and PI3K/AKT/mTOR pathway
Primary transcript
A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. Exon junction complex and primary transcript are RNA.
See Exon junction complex and Primary transcript
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues.
See Exon junction complex and Protein
Protein complex
A protein complex or multiprotein complex is a group of two or more associated polypeptide chains.
See Exon junction complex and Protein complex
RBM8A
RNA-binding protein 8A is a protein that in humans is encoded by the RBM8A gene.
See Exon junction complex and RBM8A
Ribosome
Ribosomes are macromolecular machines, found within all cells, that perform biological protein synthesis (messenger RNA translation).
See Exon junction complex and Ribosome
RNA
Ribonucleic acid (RNA) is a polymeric molecule that is essential for most biological functions, either by performing the function itself (non-coding RNA) or by forming a template for the production of proteins (messenger RNA).
See Exon junction complex and RNA
RNA splicing
RNA splicing is a process in molecular biology where a newly-made precursor messenger RNA (pre-mRNA) transcript is transformed into a mature messenger RNA (mRNA). Exon junction complex and RNA splicing are RNA and Spliceosome.
See Exon junction complex and RNA splicing
RNPS1
RNA-binding protein with serine-rich domain 1 is a protein that in humans is encoded by the RNPS1 gene.
See Exon junction complex and RNPS1
Salt bridge (protein and supramolecular)
In chemistry, a salt bridge is a combination of two non-covalent interactions: hydrogen bonding and ionic bonding (Figure 1).
See Exon junction complex and Salt bridge (protein and supramolecular)
SMG1
Serine/threonine-protein kinase SMG1 is an enzyme that in humans is encoded by the SMG1 gene.
See Exon junction complex and SMG1
SRRM1
Serine/arginine repetitive matrix protein 1 is a protein that in humans is encoded by the SRRM1 gene.
See Exon junction complex and SRRM1
Stop codon
In molecular biology, a stop codon (or termination codon) is a codon (nucleotide triplet within messenger RNA) that signals the termination of the translation process of the current protein.
See Exon junction complex and Stop codon
Translation (biology)
In biology, translation is the process in living cells in which proteins are produced using RNA molecules as templates.
See Exon junction complex and Translation (biology)
UPF1
Regulator of nonsense transcripts 1 is a protein that in humans is encoded by the UPF1 gene.
See Exon junction complex and UPF1
UPF2
Regulator of nonsense transcripts 2 is a protein that in humans is encoded by the UPF2 gene.
See Exon junction complex and UPF2
UPF3B
Regulator of nonsense transcripts 3B is a protein that in humans is encoded by the UPF3B gene.
See Exon junction complex and UPF3B
References
[1] https://en.wikipedia.org/wiki/Exon_junction_complex
, UPF3B.