Haematopoiesis, the Glossary
Haematopoiesis (from Greek αἷμα, 'blood' and ποιεῖν 'to make'; also hematopoiesis in American English; sometimes also h(a)emopoiesis) is the formation of blood cellular components.[1]
Table of Contents
105 relations: Acute lymphoblastic leukemia, Acute myeloid leukemia, American English, Ancient Greek, Apoptosis, Asymmetric cell division, B cell, Band cell, Basophil, Blood, Blood islands, Bone marrow, Cardiovascular disease, CCAAT-enhancer-binding proteins, Cell adhesion molecule, Cellular differentiation, CFU-E, CFU-GEMM, CFU-GM, CFU-Meg, Clonal hematopoiesis, Coagulation, Colony-stimulating factor, DNA-binding domain, Eosinophil, Erythropoiesis, Erythropoiesis-stimulating agent, Erythropoietin, Extramedullary hematopoiesis, Gastrointestinal tract, GATA1, Gene expression, GFI1, Glycoprotein, Granulocyte, Granulocyte colony-stimulating factor, Granulocyte-macrophage colony-stimulating factor, Granulopoiesis, Hematopoietic stem cell, Homogeneity and heterogeneity, Innate immune system, Interleukin, Interleukin 2, Interleukin 3, Interleukin 6, Interleukin 7, IRF8, KEGG, Kidney, Leukocyte extravasation, ... Expand index (55 more) »
- Hematopoiesis
Acute lymphoblastic leukemia
Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes.
See Haematopoiesis and Acute lymphoblastic leukemia
Acute myeloid leukemia
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production.
See Haematopoiesis and Acute myeloid leukemia
American English
American English (AmE), sometimes called United States English or U.S. English, is the set of varieties of the English language native to the United States.
See Haematopoiesis and American English
Ancient Greek
Ancient Greek (Ἑλληνῐκή) includes the forms of the Greek language used in ancient Greece and the ancient world from around 1500 BC to 300 BC.
See Haematopoiesis and Ancient Greek
Apoptosis
Apoptosis (from falling off) is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast.
See Haematopoiesis and Apoptosis
Asymmetric cell division
An asymmetric cell division produces two daughter cells with different cellular fates.
See Haematopoiesis and Asymmetric cell division
B cell
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.
Band cell
A band cell (also called band neutrophil, band form or stab cell) is a cell undergoing granulopoiesis, derived from a metamyelocyte, and leading to a mature granulocyte. Haematopoiesis and band cell are Histology.
See Haematopoiesis and Band cell
Basophil
Basophils are a type of white blood cell.
See Haematopoiesis and Basophil
Blood
Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells.
Blood islands
Blood islands are structures around the developing embryo which lead to many different parts of the circulatory system.
See Haematopoiesis and Blood islands
Bone marrow
Bone marrow is a semi-solid tissue found within the spongy (also known as cancellous) portions of bones. Haematopoiesis and bone marrow are hematopoiesis.
See Haematopoiesis and Bone marrow
Cardiovascular disease
Cardiovascular disease (CVD) is any disease involving the heart or blood vessels.
See Haematopoiesis and Cardiovascular disease
CCAAT-enhancer-binding proteins
CCAAT-enhancer-binding proteins (or C/EBPs) is a family of transcription factors composed of six members, named from C/EBPα to C/EBPζ.
See Haematopoiesis and CCAAT-enhancer-binding proteins
Cell adhesion molecule
Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion.
See Haematopoiesis and Cell adhesion molecule
Cellular differentiation
Cellular differentiation is the process in which a stem cell changes from one type to a differentiated one.
See Haematopoiesis and Cellular differentiation
CFU-E
CFU-E stands for '''Colony Forming Unit-Erythroid'''.
CFU-GEMM
CFU-GEMM is a colony forming unit that generates myeloid cells.
See Haematopoiesis and CFU-GEMM
CFU-GM
CFU-GM (Colony Forming Unit–Granulocyte–Macrophage), also known as granulocyte–macrophage progenitor (GMP), is a colony forming unit.
CFU-Meg
CFU-Meg is a colony forming unit.
See Haematopoiesis and CFU-Meg
Clonal hematopoiesis
Clonal hematopoiesis of indeterminate potential, or CHIP, is a common aging-related phenomenon in which hematopoietic stem cells (HSCs) or other early blood cell progenitors contribute to the formation of a genetically distinct subpopulation of blood cells.
See Haematopoiesis and Clonal hematopoiesis
Coagulation
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot.
See Haematopoiesis and Coagulation
Colony-stimulating factor
Colony-stimulating factors (CSFs) are secreted glycoproteins that bind to receptor proteins on the surfaces of committed progenitors in the bone marrow, thereby activating intracellular signaling pathways that can cause the cells to proliferate and differentiate into a specific kind of blood cell (usually white blood cells.
See Haematopoiesis and Colony-stimulating factor
DNA-binding domain
A DNA-binding domain (DBD) is an independently folded protein domain that contains at least one structural motif that recognizes double- or single-stranded DNA.
See Haematopoiesis and DNA-binding domain
Eosinophil
Eosinophils, sometimes called eosinophiles or, less commonly, acidophils, are a variety of white blood cells and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates. Along with mast cells and basophils, they also control mechanisms associated with allergy and asthma.
See Haematopoiesis and Eosinophil
Erythropoiesis
Erythropoiesis (from Greek 'erythro' meaning "red" and 'poiesis' "to make") is the process which produces red blood cells (erythrocytes), which is the development from erythropoietic stem cell to mature red blood cell. Haematopoiesis and Erythropoiesis are hematopoiesis.
See Haematopoiesis and Erythropoiesis
Erythropoiesis-stimulating agent
Erythropoiesis-stimulating agents (ESA) are medications which stimulate the bone marrow to make red blood cells.
See Haematopoiesis and Erythropoiesis-stimulating agent
Erythropoietin
Erythropoietin (EPO), also known as erythropoetin, haematopoietin, or haemopoietin, is a glycoprotein cytokine secreted mainly by the kidneys in response to cellular hypoxia; it stimulates red blood cell production (erythropoiesis) in the bone marrow.
See Haematopoiesis and Erythropoietin
Extramedullary hematopoiesis (EMH or sometimes EH) refers to hematopoiesis occurring outside of the medulla of the bone (bone marrow). Haematopoiesis and Extramedullary hematopoiesis are hematopoiesis and Histology.
See Haematopoiesis and Extramedullary hematopoiesis
Gastrointestinal tract
The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans and other animals, including the esophagus, stomach, and intestines.
See Haematopoiesis and Gastrointestinal tract
GATA1
GATA-binding factor 1 or GATA-1 (also termed Erythroid transcription factor) is the founding member of the GATA family of transcription factors.
Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, proteins or non-coding RNA, and ultimately affect a phenotype.
See Haematopoiesis and Gene expression
GFI1
Zinc finger protein Gfi-1 is a transcriptional repressor that in humans is encoded by the GFI1 gene.
Glycoprotein
Glycoproteins are proteins which contain oligosaccharide (sugar) chains covalently attached to amino acid side-chains.
See Haematopoiesis and Glycoprotein
Granulocyte
Granulocytes are cells in the innate immune system characterized by the presence of specific granules in their cytoplasm.
See Haematopoiesis and Granulocyte
Granulocyte colony-stimulating factor
Granulocyte colony-stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream.
See Haematopoiesis and Granulocyte colony-stimulating factor
Granulocyte-macrophage colony-stimulating factor
Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts that functions as a cytokine.
See Haematopoiesis and Granulocyte-macrophage colony-stimulating factor
Granulopoiesis
Granulopoiesis (or granulocytopoiesis) is a part of haematopoiesis, that leads to the production of granulocytes. Haematopoiesis and Granulopoiesis are hematopoiesis.
See Haematopoiesis and Granulopoiesis
Hematopoietic stem cell
Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells.
See Haematopoiesis and Hematopoietic stem cell
Homogeneity and heterogeneity
Homogeneity and heterogeneity are concepts relating to the uniformity of a substance, process or image.
See Haematopoiesis and Homogeneity and heterogeneity
Innate immune system
The innate immune system or nonspecific immune system is one of the two main immunity strategies (the other being the adaptive immune system) in vertebrates.
See Haematopoiesis and Innate immune system
Interleukin
Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells.
See Haematopoiesis and Interleukin
Interleukin 2
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system.
See Haematopoiesis and Interleukin 2
Interleukin 3
Interleukin 3 (IL-3) is a protein that in humans is encoded by the IL3 gene localized on chromosome 5q31.1.
See Haematopoiesis and Interleukin 3
Interleukin 6
Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine.
See Haematopoiesis and Interleukin 6
Interleukin 7
Interleukin 7 (IL-7) is a protein that in humans is encoded by the IL7 gene.
See Haematopoiesis and Interleukin 7
IRF8
Interferon regulatory factor 8 (IRF8) also known as interferon consensus sequence-binding protein (ICSBP), is a protein that in humans is encoded by the IRF8 gene.
KEGG
KEGG (Kyoto Encyclopedia of Genes and Genomes) is a collection of databases dealing with genomes, biological pathways, diseases, drugs, and chemical substances.
Kidney
In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation.
In immunology, leukocyte extravasation (also commonly known as leukocyte adhesion cascade or diapedesis – the passage of cells through the intact vessel wall) is the movement of leukocytes (white blood cells) out of the circulatory system (extravasation) and towards the site of tissue damage or infection.
See Haematopoiesis and Leukocyte extravasation
Liver
The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.
Lymph node
A lymph node, or lymph gland, is a kidney-shaped organ of the lymphatic system and the adaptive immune system.
See Haematopoiesis and Lymph node
Lymphatic system
The lymphatic system, or lymphoid system, is an organ system in vertebrates that is part of the immune system, and complementary to the circulatory system.
See Haematopoiesis and Lymphatic system
Lymphoblast
A lymphoblast is a modified naive lymphocyte with altered cell morphology.
See Haematopoiesis and Lymphoblast
Lymphocyte
A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates.
See Haematopoiesis and Lymphocyte
Lymphopoiesis
Lymphopoiesis (lĭm'fō-poi-ē'sĭs) (or lymphocytopoiesis) is the generation of lymphocytes, one of the five types of white blood cells (WBCs). Haematopoiesis and Lymphopoiesis are hematopoiesis and Histology.
See Haematopoiesis and Lymphopoiesis
Lynne Selwood
Lynne Selwood FRSV (née Bedford) is an Australian reproductive biologist whose work focuses on marsupials.
See Haematopoiesis and Lynne Selwood
Macrophage
Macrophages (abbreviated Mφ, MΦ or MP) are a type of white blood cell of the innate immune system that engulf and digest pathogens, such as cancer cells, microbes, cellular debris, and foreign substances, which do not have proteins that are specific to healthy body cells on their surface.
See Haematopoiesis and Macrophage
Macrophage colony-stimulating factor
The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which causes hematopoietic stem cells to differentiate into macrophages or other related cell types.
See Haematopoiesis and Macrophage colony-stimulating factor
Mast cell
A mast cell (also known as a mastocyte or a labrocyte) is a resident cell of connective tissue that contains many granules rich in histamine and heparin.
See Haematopoiesis and Mast cell
Megakaryoblast
A megakaryoblast (mega- + karyo + -blast, "large-nucleus immature cell") is a precursor cell to a promegakaryocyte.
See Haematopoiesis and Megakaryoblast
Megakaryocyte
A megakaryocyte (mega- + karyo- + -cyte, "large-nucleus cell") is a large bone marrow cell with a lobated nucleus that produces blood platelets (thrombocytes), which are necessary for normal clotting.
See Haematopoiesis and Megakaryocyte
A metamyelocyte is a cell undergoing granulopoiesis, derived from a myelocyte, and leading to a band cell. Haematopoiesis and metamyelocyte are Histology.
See Haematopoiesis and Metamyelocyte
MicroRNA
MicroRNA (miRNA) are small, single-stranded, non-coding RNA molecules containing 21 to 23 nucleotides.
See Haematopoiesis and MicroRNA
Monoblast
Monoblasts are the committed progenitor cells that differentiated from a committed macrophage or dendritic cell precursor (MDP) in the process of hematopoiesis.
See Haematopoiesis and Monoblast
Monocyte
Monocytes are a type of leukocyte or white blood cell.
See Haematopoiesis and Monocyte
Monocytopoiesis
Monocytopoiesis is the process which leads to the production of monocytes (and, subsequently, macrophages). Haematopoiesis and Monocytopoiesis are hematopoiesis.
See Haematopoiesis and Monocytopoiesis
Mutation
In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA.
See Haematopoiesis and Mutation
Myeloblast
The myeloblast is a unipotent stem cell which differentiates into the effectors of the granulocyte series.
See Haematopoiesis and Myeloblast
Myelocyte
A myelocyte is a young cell of the granulocytic series, occurring normally in bone marrow (can be found in circulating blood when caused by certain diseases).
See Haematopoiesis and Myelocyte
Myeloid tissue
Myeloid tissue, in the bone marrow sense of the word myeloid (myelo- + -oid), is tissue of bone marrow, of bone marrow cell lineage, or resembling bone marrow, and myelogenous tissue (myelo- + -genous) is any tissue of, or arising from, bone marrow; in these senses the terms are usually used synonymously, as for example with chronic myeloid/myelogenous leukemia.
See Haematopoiesis and Myeloid tissue
Myelopoiesis
In hematology, myelopoiesis in the broadest sense of the term is the production of bone marrow and of all cells that arise from it, namely, all blood cells. Haematopoiesis and myelopoiesis are hematopoiesis and Histology.
See Haematopoiesis and Myelopoiesis
Natural killer cell
Natural killer cells, also known as NK cells or large granular lymphocytes (LGL), are a type of cytotoxic lymphocyte critical to the innate immune system.
See Haematopoiesis and Natural killer cell
Neutrophil
Neutrophils (also known as neutrocytes, heterophils or polymorphonuclear leukocytes) are a type of white blood cell.
See Haematopoiesis and Neutrophil
NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription of DNA, cytokine production and cell survival.
Nucleated red blood cell
A nucleated red blood cell (NRBC), also known by several other names, is a red blood cell that contains a cell nucleus.
See Haematopoiesis and Nucleated red blood cell
Osteoclast
An osteoclast is a type of bone cell that breaks down bone tissue.
See Haematopoiesis and Osteoclast
PAX5
Paired box protein Pax-5 is a protein that in humans is encoded by the PAX5 gene.
Philadelphia chromosome
The Philadelphia chromosome or Philadelphia translocation (Ph) is a specific genetic abnormality in chromosome 22 of leukemia cancer cells (particularly chronic myeloid leukemia (CML) cells).
See Haematopoiesis and Philadelphia chromosome
Platelet
Platelets or thrombocytes are a blood component whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.
See Haematopoiesis and Platelet
Proerythroblast
A proerythroblast (or rubriblast, or pronormoblast) is the earliest of four stages in development of the normoblast.
See Haematopoiesis and Proerythroblast
Progenitor cell
A progenitor cell is a biological cell that can differentiate into a specific cell type.
See Haematopoiesis and Progenitor cell
Prolymphocyte
A prolymphocyte is a white blood cell with a certain state of cellular differentiation in lymphocytopoiesis.
See Haematopoiesis and Prolymphocyte
Promegakaryocyte
A promegakaryocyte is a precursor cell for a megakaryocyte.
See Haematopoiesis and Promegakaryocyte
A promonocyte (or premonocyte) is a cell arising from a monoblast and developing into a monocyte.
See Haematopoiesis and Promonocyte
Promyelocyte
A promyelocyte (or progranulocyte) is a granulocyte precursor, developing from the myeloblast and developing into the myelocyte.
See Haematopoiesis and Promyelocyte
Protein dimer
In biochemistry, a protein dimer is a macromolecular complex or multimer formed by two protein monomers, or single proteins, which are usually non-covalently bound.
See Haematopoiesis and Protein dimer
Red blood cell
Red blood cells (RBCs), referred to as erythrocytes (with -cyte translated as 'cell' in modern usage) in academia and medical publishing, also known as red cells, erythroid cells, and rarely haematids, are the most common type of blood cell and the vertebrate's principal means of delivering oxygen to the body tissues—via blood flow through the circulatory system.
See Haematopoiesis and Red blood cell
Reticulocyte
In hematology, reticulocytes are immature red blood cells (RBCs).
See Haematopoiesis and Reticulocyte
Sca-1
Sca-1 stands for "Stem cells antigen-1" (official gene symbol: Ly6a).
Signal transduction
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events.
See Haematopoiesis and Signal transduction
SPI1
Transcription factor PU.1 is a protein that in humans is encoded by the SPI1 gene.
Spleen
The spleen is an organ found in almost all vertebrates.
Stem cell
In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely to produce more of the same stem cell.
See Haematopoiesis and Stem cell
Stem cell factor
Stem cell factor (also known as SCF, KIT-ligand, KL, or steel factor) is a cytokine that binds to the c-KIT receptor (CD117).
See Haematopoiesis and Stem cell factor
Stromal cell
Stromal cells, or mesenchymal stromal cells, are differentiating cells found in abundance within bone marrow but can also be seen all around the body.
See Haematopoiesis and Stromal cell
T cell
T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response.
T helper cell
The T helper cells (Th cells), also known as CD4+ cells or CD4-positive cells, are a type of T cell that play an important role in the adaptive immune system.
See Haematopoiesis and T helper cell
Thrombopoiesis
Thrombopoiesis is the formation of thrombocytes (blood platelets) in the bone marrow. Haematopoiesis and Thrombopoiesis are hematopoiesis.
See Haematopoiesis and Thrombopoiesis
Thrombopoietin
Thrombopoietin (THPO) also known as megakaryocyte growth and development factor (MGDF) is a protein that in humans is encoded by the THPO gene.
See Haematopoiesis and Thrombopoietin
Thymus
The thymus (thymuses or thymi) is a specialized primary lymphoid organ of the immune system.
Transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.
See Haematopoiesis and Transcription factor
Vertebrate
Vertebrates are deuterostomal animals with bony or cartilaginous axial endoskeleton — known as the vertebral column, spine or backbone — around and along the spinal cord, including all fish, amphibians, reptiles, birds and mammals.
See Haematopoiesis and Vertebrate
White blood cell
White blood cells (scientific name leukocytes), also called immune cells or immunocytes, are cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.
See Haematopoiesis and White blood cell
Zinc finger
A zinc finger is a small protein structural motif that is characterized by the coordination of one or more zinc ions (Zn2+) which stabilizes the fold.
See Haematopoiesis and Zinc finger
See also
Hematopoiesis
- Bone marrow
- Erythropoiesis
- Erythropoiesis-stimulating agents
- Extramedullary hematopoiesis
- Granulopoiesis
- Haematopoiesis
- Hemopoietic growth factor
- Leukopoiesis
- Lymphopoiesis
- Metabolic regulation of hematopoiesis
- Monocytopoiesis
- Myelopoiesis
- Thrombopoiesis
References
[1] https://en.wikipedia.org/wiki/Haematopoiesis
Also known as Blood cell formation, Blood cell production, Blood formation, Determinism theory of hematopoiesis, Haemapoiesis, Haematopoeisis, Haematopoesis, Haematopoietic, Haematopoietic growth factor, Haematopoisis, Haematosis, Haemogenesis, Haemopoeisis, Haemopoiesis, Haemotopoiesis, Hemangiogenesis, Hemapoiesis, Hematapoiesis, Hematon, Hematopoeisis, Hematopoesis, Hematopoiesis, Hematopoietic, Hemopoeisis, Hemopoiesis, Hemopoietic, Hemopoietic system, Stochastic theory of hematopoiesis.
, Liver, Lymph node, Lymphatic system, Lymphoblast, Lymphocyte, Lymphopoiesis, Lynne Selwood, Macrophage, Macrophage colony-stimulating factor, Mast cell, Megakaryoblast, Megakaryocyte, Metamyelocyte, MicroRNA, Monoblast, Monocyte, Monocytopoiesis, Mutation, Myeloblast, Myelocyte, Myeloid tissue, Myelopoiesis, Natural killer cell, Neutrophil, NF-κB, Nucleated red blood cell, Osteoclast, PAX5, Philadelphia chromosome, Platelet, Proerythroblast, Progenitor cell, Prolymphocyte, Promegakaryocyte, Promonocyte, Promyelocyte, Protein dimer, Red blood cell, Reticulocyte, Sca-1, Signal transduction, SPI1, Spleen, Stem cell, Stem cell factor, Stromal cell, T cell, T helper cell, Thrombopoiesis, Thrombopoietin, Thymus, Transcription factor, Vertebrate, White blood cell, Zinc finger.