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Idazoxan, the Glossary

Index Idazoxan

Idazoxan (INN) is a drug which is used in scientific research.[1]

Table of Contents

  1. 23 relations: Adrenergic receptor, Alpha-2 adrenergic receptor, Alpha-2A adrenergic receptor, Alzheimer's disease, Antidepressant, Antipsychotic, Dopamine, Drug, Efaroxan, Ethylenediamine, Fluparoxan, Imidazoline receptor, Imiloxan, International nonproprietary name, Neurotransmission, Norepinephrine, Pathogenesis, Pinner reaction, Prefrontal cortex, Racemic mixture, Receptor antagonist, Schizophrenia, Scientific method.

  2. Alpha blockers
  3. Benzodioxans
  4. Imidazoline antagonists

Adrenergic receptor

The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications like beta blockers, beta-2 (β2) agonists and alpha-2 (α2) agonists, which are used to treat high blood pressure and asthma, for example.

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Alpha-2 adrenergic receptor

The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein.

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Alpha-2A adrenergic receptor

The alpha-2A adrenergic receptor (α2A adrenoceptor), also known as ADRA2A, is an α2 adrenergic receptor, and also denotes the human gene encoding it.

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Alzheimer's disease

Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens, and is the cause of 60–70% of cases of dementia.

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Antidepressant

Antidepressants are a class of medications used to treat major depressive disorder, anxiety disorders, chronic pain, and addiction.

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Antipsychotic

Antipsychotics, previously known as neuroleptics and major tranquilizers, are a class of psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but also in a range of other psychotic disorders.

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Dopamine

Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells.

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Drug

A drug is any chemical substance other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect.

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Efaroxan

Efaroxan is an α2-adrenergic receptor antagonist and antagonist of the imidazoline receptor. Idazoxan and Efaroxan are imidazolines.

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Ethylenediamine

Ethylenediamine (abbreviated as en when a ligand) is the organic compound with the formula C2H4(NH2)2.

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Fluparoxan

Fluparoxan (developmental code name GR50360A) is a potent α2-adrenergic receptor antagonist (pKB.

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Imidazoline receptor

Imidazoline receptors are the primary receptors on which clonidine and other imidazolines act.

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Imiloxan

Imiloxan is a drug which is used in scientific research. Idazoxan and Imiloxan are alpha blockers, Benzodioxans and imidazolines.

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International nonproprietary name

An international nonproprietary name (INN) is an official generic and nonproprietary name given to a pharmaceutical drug or an active ingredient.

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Neurotransmission

Neurotransmission (Latin: transmissio "passage, crossing" from transmittere "send, let through") is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron), and bind to and react with the receptors on the dendrites of another neuron (the postsynaptic neuron) a short distance away.

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Norepinephrine

Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone, neurotransmitter and neuromodulator.

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Pathogenesis

In pathology, pathogenesis is the process by which a disease or disorder develops.

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Pinner reaction

The Pinner reaction refers to the acid catalysed reaction of a nitrile with an alcohol to form an imino ester salt (alkyl imidate salt); this is sometimes referred to as a Pinner salt.

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Prefrontal cortex

In mammalian brain anatomy, the prefrontal cortex (PFC) covers the front part of the frontal lobe of the cerebral cortex.

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Racemic mixture

In chemistry, a racemic mixture or racemate is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule or salt.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

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Schizophrenia

Schizophrenia is a mental disorder characterized by reoccurring episodes of psychosis that are correlated with a general misperception of reality.

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Scientific method

The scientific method is an empirical method for acquiring knowledge that has characterized the development of science since at least the 17th century.

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See also

Alpha blockers

Benzodioxans

Imidazoline antagonists

  • Idazoxan

References

[1] https://en.wikipedia.org/wiki/Idazoxan