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Inbred strain, the Glossary

Index Inbred strain

Inbred strains (also called inbred lines, or rarely for animals linear animals) are individuals of a particular species which are nearly identical to each other in genotype due to long inbreeding.[1]

Table of Contents

  1. 43 relations: Arabidopsis thaliana, Backcrossing, BALB/c, C57BL/6, Cloning, Coefficient of inbreeding, Coisogenic strain, Congenic, Flower, FlyBase, GAL4/UAS system, Genealogy, Genetic diversity, Genetic drift, Genetically modified animal, Genome, Genotype, Green fluorescent protein, Heterosis, Immune tolerance, Inbreeding, Inbreeding depression, Jackson Laboratory, Japanese rice fish, Laboratory rat, Locus (genetics), Major histocompatibility complex, McGraw Hill Education, Model organism, Monoclonal antibody, Outcrossing, Phenotype, Pollen, Quantitative trait locus, Recombinant inbred strain, Robert Tryon, Self-pollination, Sewall Wright, Species, Tryon's Rat Experiment, Wild type, Zebrafish, Zygosity.

  2. Breeding

Arabidopsis thaliana

Arabidopsis thaliana, the thale cress, mouse-ear cress or arabidopsis, is a small plant from the mustard family (Brassicaceae), native to Eurasia and Africa.

See Inbred strain and Arabidopsis thaliana

Backcrossing

Backcrossing is a crossing of a hybrid with one of its parents or an individual genetically similar to its parent, to achieve offspring with a genetic identity closer to that of the parent. Inbred strain and Backcrossing are breeding.

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BALB/c

BALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived.

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C57BL/6

C57BL/6, often referred to as "C57 black 6", "B6", "C57" or "black 6", is a common inbred strain of laboratory mouse.

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Cloning

Cloning is the process of producing individual organisms with identical genomes, either by natural or artificial means.

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Coefficient of inbreeding

The coefficient of inbreeding (COI) is a number measuring how inbred an individual is. Inbred strain and coefficient of inbreeding are breeding and population genetics.

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Coisogenic strain

Coisogenic strains are one type of inbred strain that differs by a mutation at a single locus and all of the other loci are identical.

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Congenic

In genetics, two organisms that differ in only one locus and a linked segment of chromosome are defined as congenic.

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Flower

A flower, also known as a bloom or blossom, is the reproductive structure found in flowering plants (plants of the division Angiospermae).

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FlyBase

FlyBase is an online bioinformatics database and the primary repository of genetic and molecular data for the insect family Drosophilidae.

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GAL4/UAS system

The GAL4-UAS system is a biochemical method used to study gene expression and function in organisms such as the fruit fly.

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Genealogy

Genealogy is the study of families, family history, and the tracing of their lineages.

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Genetic diversity

Genetic diversity is the total number of genetic characteristics in the genetic makeup of a species. Inbred strain and genetic diversity are population genetics.

See Inbred strain and Genetic diversity

Genetic drift

Genetic drift, also known as random genetic drift, allelic drift or the Wright effect, refers to random fluctuations in the frequency of an existing gene variant (allele) in a population. Inbred strain and genetic drift are population genetics.

See Inbred strain and Genetic drift

Genetically modified animal

Genetically modified animals are animals that have been genetically modified for a variety of purposes including producing drugs, enhancing yields, increasing resistance to disease, etc.

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Genome

In the fields of molecular biology and genetics, a genome is all the genetic information of an organism.

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Genotype

The genotype of an organism is its complete set of genetic material.

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Green fluorescent protein

The green fluorescent protein (GFP) is a protein that exhibits green fluorescence when exposed to light in the blue to ultraviolet range.

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Heterosis

Heterosis, hybrid vigor, or outbreeding enhancement is the improved or increased function of any biological quality in a hybrid offspring. Inbred strain and Heterosis are breeding.

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Immune tolerance

Immune tolerance, also known as immunological tolerance or immunotolerance, refers to the immune system's state of unresponsiveness to substances or tissues that would otherwise trigger an immune response.

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Inbreeding

Inbreeding is the production of offspring from the mating or breeding of individuals or organisms that are closely related genetically. Inbred strain and Inbreeding are breeding and population genetics.

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Inbreeding depression

Inbreeding depression is the reduced biological fitness that has the potential to result from inbreeding (the breeding of related individuals). Inbred strain and inbreeding depression are breeding and population genetics.

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Jackson Laboratory

The Jackson Laboratory (often abbreviated as JAX) is an independent, non-profit biomedical research institution which was founded by Clarence Cook Little in 1929.

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Japanese rice fish

The Japanese rice fish (Oryzias latipes), also known as the medaka, is a member of genus Oryzias (ricefish), the only genus in the subfamily Oryziinae.

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Laboratory rat

Laboratory rats or lab rats are strains of the rat subspecies Rattus norvegicus domestica (Domestic Norwegian rat) which are bred and kept for scientific research.

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Locus (genetics)

In genetics, a locus (loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located.

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Major histocompatibility complex

The major histocompatibility complex (MHC) is a large locus on vertebrate DNA containing a set of closely linked polymorphic genes that code for cell surface proteins essential for the adaptive immune system.

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McGraw Hill Education

McGraw Hill is an American publishing company for educational content, software, and services for pre-K through postgraduate education.

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Model organism

A model organism (often shortened to model) is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the model organism will provide insight into the workings of other organisms.

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Monoclonal antibody

A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell lineage made by cloning a unique white blood cell.

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Outcrossing

Out-crossing or out-breeding is the technique of crossing between different breeds. Inbred strain and Outcrossing are breeding.

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Phenotype

In genetics, the phenotype is the set of observable characteristics or traits of an organism.

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Pollen

Pollen is a powdery substance produced by most types of flowers of seed plants for the purpose of sexual reproduction.

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Quantitative trait locus

A quantitative trait locus (QTL) is a locus (section of DNA) that correlates with variation of a quantitative trait in the phenotype of a population of organisms.

See Inbred strain and Quantitative trait locus

Recombinant inbred strain

A recombinant inbred strain or recombinant inbred line (RIL) is an organism with chromosomes that incorporate an essentially permanent set of recombination events between chromosomes inherited from two or more inbred strains. Inbred strain and recombinant inbred strain are population genetics.

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Robert Tryon

Robert Choate Tryon (September 4, 1901 – September 27, 1967) was an American behavioral psychologist, who pioneered the study of hereditary trait inheritance and learning in animals.

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Self-pollination

Self-pollination is a form of pollination in which pollen from one plant arrives at the stigma of a flower (in flowering plants) or at the ovule (in gymnosperms) of the same plant.

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Sewall Wright

Sewall Green Wright FRS (For) Honorary FRSE (December 21, 1889March 3, 1988) was an American geneticist known for his influential work on evolutionary theory and also for his work on path analysis.

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Species

A species (species) is often defined as the largest group of organisms in which any two individuals of the appropriate sexes or mating types can produce fertile offspring, typically by sexual reproduction.

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Tryon's Rat Experiment

Tryon's Rat Experiment is a psychology experiment conducted by Robert Tryon in 1940 and published in the Yearbook of the National Society for Studies in Education.

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Wild type

The wild type (WT) is the phenotype of the typical form of a species as it occurs in nature.

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Zebrafish

The zebrafish (Danio rerio) is a freshwater fish belonging to the minnow family (Cyprinidae) of the order Cypriniformes.

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Zygosity

Zygosity (the noun, zygote, is from the Greek "yoked," from "yoke") is the degree to which both copies of a chromosome or gene have the same genetic sequence.

See Inbred strain and Zygosity

See also

Breeding

References

[1] https://en.wikipedia.org/wiki/Inbred_strain

Also known as Inbred line, Inbred strains, Isogenic line, Linear animal, Near-isogenic line.