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Leucine zipper, the Glossary

A leucine zipper (or leucine scissors) is a common three-dimensional structural motif in proteins.^[1]

45 relations: Alpha helix, Amino acid, Amphiphile, Apoptosis, Arginine, Binding protein, BZIP domain, Cancer, CCAAT-enhancer-binding proteins, Chemical specificity, Circadian rhythm, Coiled coil, CREB, DBP (gene), DNA, DNA supercoil, Eukaryote, Forkhead box protein O1, Heptad repeat, Histone deacetylase 2, Hydrophile, Hydrophobe, Leucine, Lysine, MAX (gene), Monomer, MXD1, Myc, Natural killer cell, NFIL3, Nucleic acid double helix, Palindromic sequence, Protein c-Fos, Protein dimer, Protein primary structure, Protein–protein interaction, Side chain, Solvent, Structural motif, T helper cell, TRAIL, Transcription (biology), Transcription factor, Transcription factor Jun, Van der Waals force.
DNA-binding substances

Alpha helix

An alpha helix (or α-helix) is a sequence of amino acids in a protein that are twisted into a coil (a helix). Leucine zipper and alpha helix are protein structural motifs.

See Leucine zipper and Alpha helix

Amino acid

Amino acids are organic compounds that contain both amino and carboxylic acid functional groups.

See Leucine zipper and Amino acid

An amphiphile (from the Greek αμφις amphis, both, and φιλíα philia, love, friendship), or amphipath, is a chemical compound possessing both hydrophilic (water-loving, polar) and lipophilic (fat-loving) properties.

See Leucine zipper and Amphiphile

Apoptosis

Apoptosis (from falling off) is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast.

See Leucine zipper and Apoptosis

Arginine

Arginine is the amino acid with the formula (H2N)(HN)CN(H)(CH2)3CH(NH2)CO2H.

See Leucine zipper and Arginine

Binding protein

A binding protein is any protein that acts as an agent to bind two or more molecules together.

See Leucine zipper and Binding protein

BZIP domain

The Basic Leucine Zipper Domain (bZIP domain) is found in many DNA binding eukaryotic proteins.

See Leucine zipper and BZIP domain

Cancer

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

See Leucine zipper and Cancer

CCAAT-enhancer-binding proteins

CCAAT-enhancer-binding proteins (or C/EBPs) is a family of transcription factors composed of six members, named from C/EBPα to C/EBPζ.

See Leucine zipper and CCAAT-enhancer-binding proteins

Chemical specificity

Chemical specificity is the ability of binding site of a macromolecule (such as a protein) to bind specific ligands.

See Leucine zipper and Chemical specificity

Circadian rhythm

A circadian rhythm, or circadian cycle, is a natural oscillation that repeats roughly every 24 hours.

See Leucine zipper and Circadian rhythm

Coiled coil

A coiled coil is a structural motif in proteins in which 2–7 alpha-helices are coiled together like the strands of a rope.

See Leucine zipper and Coiled coil

CREB

CREB-TF (CREB, cAMP response element-binding protein) is a cellular transcription factor.

See Leucine zipper and CREB

DBP (gene)

D site of albumin promoter (albumin D-box) binding protein, also known as DBP, is a protein which in humans is encoded by the DBP gene.

See Leucine zipper and DBP (gene)

DNA

Deoxyribonucleic acid (DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix.

See Leucine zipper and DNA

DNA supercoil

DNA supercoiling refers to the amount of twist in a particular DNA strand, which determines the amount of strain on it.

See Leucine zipper and DNA supercoil

Eukaryote

The eukaryotes constitute the domain of Eukarya or Eukaryota, organisms whose cells have a membrane-bound nucleus.

See Leucine zipper and Eukaryote

Forkhead box protein O1

Forkhead box protein O1 (FOXO1), also known as forkhead in rhabdomyosarcoma (FKHR), is a protein that in humans is encoded by the FOXO1 gene.

See Leucine zipper and Forkhead box protein O1

Heptad repeat

The heptad repeat is an example of a structural motif that consists of a repeating pattern of seven amino acids: where H represents hydrophobic residues, C represents, typically, charged residues, and P represents polar (and, therefore, hydrophilic) residues. Leucine zipper and heptad repeat are protein structural motifs.

See Leucine zipper and Heptad repeat

Histone deacetylase 2

Histone deacetylase 2 (HDAC2) is an enzyme that in humans is encoded by the HDAC2 gene.

See Leucine zipper and Histone deacetylase 2

Hydrophile

A hydrophile is a molecule or other molecular entity that is attracted to water molecules and tends to be dissolved by water.

See Leucine zipper and Hydrophile

Hydrophobe

In chemistry, hydrophobicity is the physical property of a molecule that is seemingly repelled from a mass of water (known as a hydrophobe).

See Leucine zipper and Hydrophobe

Leucine

Leucine (symbol Leu or L) is an essential amino acid that is used in the biosynthesis of proteins.

See Leucine zipper and Leucine

Lysine

Lysine (symbol Lys or K) is an α-amino acid that is a precursor to many proteins.

See Leucine zipper and Lysine

MAX (gene)

MAX (also known as myc-associated factor X) is a gene that in humans encodes the MAX transcription factor.

See Leucine zipper and MAX (gene)

Monomer

A monomer (mono-, "one" + -mer, "part") is a molecule that can react together with other monomer molecules to form a larger polymer chain or three-dimensional network in a process called polymerization.

See Leucine zipper and Monomer

MXD1

MAD protein is a protein that in humans is encoded by the MXD1 gene.

See Leucine zipper and MXD1

Myc

Myc is a family of regulator genes and proto-oncogenes that code for transcription factors.

See Leucine zipper and Myc

Natural killer cell

Natural killer cells, also known as NK cells or large granular lymphocytes (LGL), are a type of cytotoxic lymphocyte critical to the innate immune system.

See Leucine zipper and Natural killer cell

NFIL3

Nuclear factor, interleukin 3 regulated, also known as NFIL3 or E4BP4 is a protein which in humans is encoded by the NFIL3 gene.

See Leucine zipper and NFIL3

Nucleic acid double helix

In molecular biology, the term double helix refers to the structure formed by double-stranded molecules of nucleic acids such as DNA.

See Leucine zipper and Nucleic acid double helix

Palindromic sequence

A palindromic sequence is a nucleic acid sequence in a double-stranded DNA or RNA molecule whereby reading in a certain direction (e.g. 5' to 3') on one strand is identical to the sequence in the same direction (e.g. 5' to 3') on the complementary strand.

See Leucine zipper and Palindromic sequence

Protein c-Fos

Protein c-Fos is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos.

See Leucine zipper and Protein c-Fos

Protein dimer

In biochemistry, a protein dimer is a macromolecular complex or multimer formed by two protein monomers, or single proteins, which are usually non-covalently bound.

See Leucine zipper and Protein dimer

Protein primary structure

Protein primary structure is the linear sequence of amino acids in a peptide or protein.

See Leucine zipper and Protein primary structure

Protein–protein interaction

Protein–protein interactions (PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by interactions that include electrostatic forces, hydrogen bonding and the hydrophobic effect.

See Leucine zipper and Protein–protein interaction

Side chain

In organic chemistry and biochemistry, a side chain is a chemical group that is attached to a core part of the molecule called the "main chain" or backbone.

See Leucine zipper and Side chain

Solvent

A solvent (from the Latin solvō, "loosen, untie, solve") is a substance that dissolves a solute, resulting in a solution.

See Leucine zipper and Solvent

Structural motif

In a chain-like biological molecule, such as a protein or nucleic acid, a structural motif is a common three-dimensional structure that appears in a variety of different, evolutionarily unrelated molecules. Leucine zipper and structural motif are protein structural motifs.

See Leucine zipper and Structural motif

References

[1] https://en.wikipedia.org/wiki/Leucine_zipper

Also known as Basic zipper, Basic-leucine zipper transcription factors, Leucine scissors, Leucine zipper domain, Leucine zippering, Leucine zippers, Leucine-zipper.

Leucine zipper, the Glossary

Table of Contents

See also

DNA-binding substances

References