Loperamide, the Glossary
Loperamide, sold under the brand name Imodium, among others,Drugs.com Page accessed 4 September 2015 is a medication of the opioid receptor agonist class used to decrease the frequency of diarrhea.[1]
Table of Contents
96 relations: Abdominal distension, Administrator of the Drug Enforcement Administration, Adverse drug reaction, Agonist, Angioedema, Anticholinergic, Antihistamine, Antipsychotic, Arrhythmia, Beerse, Bloating, Blood–brain barrier, Breastfeeding, Cardiotoxicity, Clostridioides difficile infection, Constipation, Contraindication, Controlled substance, Controlled Substances Act, Crohn's disease, Crystal polymorphism, Diarrhea, Diário Oficial da União, Diphenoxylate, Drug Enforcement Administration, Drug prohibition, Dysentery, Enterocolitis, Erythema multiforme, Escherichia coli O157:H7, Federal Register, Fentanyl, Fever, First pass effect, Food and Drug Administration, Francis M. Mullen, Gastrocolic reflex, Gastrointestinal tract, Generic drug, Glioblastoma, Goethe University Frankfurt, Gut (journal), Heat stroke, HIV/AIDS, Hydrate, Ileostomy, Ileus, Inflammatory bowel disease, Irinotecan, Irritable bowel syndrome, ... Expand index (46 more) »
- Antidiarrhoeals
- Butyramides
- HERG blocker
Abdominal distension
Abdominal distension occurs when substances, such as air (gas) or fluid, accumulate in the abdomen causing its expansion.
See Loperamide and Abdominal distension
Administrator of the Drug Enforcement Administration
The Administrator of the Drug Enforcement Administration is the head of the Drug Enforcement Administration, a United States federal law enforcement agency under the United States Department of Justice, tasked with combating drug trafficking and distribution within the United States.
See Loperamide and Administrator of the Drug Enforcement Administration
Adverse drug reaction
An adverse drug reaction (ADR) is a harmful, unintended result caused by taking medication.
See Loperamide and Adverse drug reaction
Agonist
An agonist is a chemical that activates a receptor to produce a biological response.
Angioedema
Angioedema is an area of swelling (edema) of the lower layer of skin and tissue just under the skin or mucous membranes.
Anticholinergic
Anticholinergics (anticholinergic agents) are substances that block the action of the acetylcholine (ACh) neurotransmitter at synapses in the central and peripheral nervous system.
See Loperamide and Anticholinergic
Antihistamine
Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies.
See Loperamide and Antihistamine
Antipsychotic
Antipsychotics, previously known as neuroleptics and major tranquilizers, are a class of psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but also in a range of other psychotic disorders.
See Loperamide and Antipsychotic
Arrhythmia
Arrhythmias, also known as cardiac arrhythmias, are irregularities in the heartbeat, including when it is too fast or too slow.
Beerse
Beerse is a municipality located in the Belgian province of Antwerp.
Bloating
Abdominal bloating (or simply bloating) is a short-term disease that affects the gastrointestinal tract.
Blood–brain barrier
The blood–brain barrier (BBB) is a highly selective semipermeable border of endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood.
See Loperamide and Blood–brain barrier
Breastfeeding
Breastfeeding, variously known as chestfeeding or nursing, is the process where breast milk is fed to a child.
See Loperamide and Breastfeeding
Cardiotoxicity
Cardiotoxicity is the occurrence of heart dysfunction as electric or muscle damage, resulting in heart toxicity.
See Loperamide and Cardiotoxicity
Clostridioides difficile infection
Clostridioides difficile infection (CDI or C-diff), also known as Clostridium difficile infection, is a symptomatic infection due to the spore-forming bacterium Clostridioides difficile.
See Loperamide and Clostridioides difficile infection
Constipation
Constipation is a bowel dysfunction that makes bowel movements infrequent or hard to pass.
See Loperamide and Constipation
Contraindication
In medicine, a contraindication is a condition (a situation or factor) that serves as a reason not to take a certain medical treatment due to the harm that it would cause the patient.
See Loperamide and Contraindication
Controlled substance
A controlled substance is generally a drug or chemical whose manufacture, possession and use is regulated by a government, such as illicitly used drugs or prescription medications that are designated by law.
See Loperamide and Controlled substance
Controlled Substances Act
The Controlled Substances Act (CSA) is the statute establishing federal U.S. drug policy under which the manufacture, importation, possession, use, and distribution of certain substances is regulated.
See Loperamide and Controlled Substances Act
Crohn's disease
Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any segment of the gastrointestinal tract.
See Loperamide and Crohn's disease
Crystal polymorphism
In crystallography, polymorphism is the phenomenon where a compound or element can crystallize into more than one crystal structure.
See Loperamide and Crystal polymorphism
Diarrhea
Diarrhea (American English), also spelled diarrhoea or diarrhœa (British English), is the condition of having at least three loose, liquid, or watery bowel movements in a day.
Diário Oficial da União
The Diário Oficial da União (literally Official Diary of the Union), abbreviated DOU, is the official journal of the federal government of Brazil.
See Loperamide and Diário Oficial da União
Diphenoxylate
Diphenoxylate is a centrally active opioid drug of the phenylpiperidine series that is used as a combination drug with atropine for the treatment of diarrhea. Loperamide and Diphenoxylate are 4-Phenylpiperidines, Antidiarrhoeals, Belgian inventions, Janssen Pharmaceutica, mu-opioid receptor agonists and synthetic opioids.
See Loperamide and Diphenoxylate
Drug Enforcement Administration
The Drug Enforcement Administration (DEA) is a United States federal law enforcement agency under the U.S. Department of Justice tasked with combating illicit drug trafficking and distribution within the U.S. It is the lead agency for domestic enforcement of the Controlled Substances Act, sharing concurrent jurisdiction with the Federal Bureau of Investigation, the U.S.
See Loperamide and Drug Enforcement Administration
Drug prohibition
The prohibition of drugs through sumptuary legislation or religious law is a common means of attempting to prevent the recreational use of certain intoxicating substances.
See Loperamide and Drug prohibition
Dysentery
Dysentery, historically known as the bloody flux, is a type of gastroenteritis that results in bloody diarrhea.
Enterocolitis
Enterocolitis is an inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon.
See Loperamide and Enterocolitis
Erythema multiforme
Erythema multiforme (EM) is a skin condition that appears with red patches evolving into target lesions, typically on both hands.
See Loperamide and Erythema multiforme
Escherichia coli O157:H7
Escherichia coli O157:H7 is a serotype of the bacterial species Escherichia coli and is one of the Shiga-like toxin–producing types of E. coli.
See Loperamide and Escherichia coli O157:H7
Federal Register
The Federal Register (FR or sometimes Fed. Reg.) is the official journal of the federal government of the United States that contains government agency rules, proposed rules, and public notices.
See Loperamide and Federal Register
Fentanyl
Fentanyl is a highly potent synthetic piperidine opioid primarily used as an analgesic. It is 20 to 40 times more potent than heroin and 100 times more potent than morphine; its primary clinical utility is in pain management for cancer patients and those recovering from painful surgeries. Fentanyl is also used as a sedative. Loperamide and Fentanyl are Belgian inventions, HERG blocker, mu-opioid receptor agonists, synthetic opioids and World Health Organization essential medicines.
Fever
Fever or pyrexia in humans is a body temperature above the normal range due to an increase in the body's temperature set point in the hypothalamus.
First pass effect
The first pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism at a specific location in the body which leads to a reduction in the concentration of the active drug before it reaches the site of action or systemic circulation.
See Loperamide and First pass effect
Food and Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services.
See Loperamide and Food and Drug Administration
Francis M. Mullen
Francis M. "Bud" Mullen, Jr. (born 14 December 1934 in New London, Connecticut) is a former executive assistant director of the Federal Bureau of Investigation (FBI) and former Administrator of the Drug Enforcement Administration (DEA).
See Loperamide and Francis M. Mullen
Gastrocolic reflex
The gastrocolic reflex or gastrocolic response is a physiological reflex that controls the motility, or peristalsis, of the gastrointestinal tract following a meal.
See Loperamide and Gastrocolic reflex
Gastrointestinal tract
The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans and other animals, including the esophagus, stomach, and intestines.
See Loperamide and Gastrointestinal tract
Generic drug
A generic drug (or simply generic) is a pharmaceutical drug that contains the same chemical substance as a drug that was originally protected by chemical patents.
See Loperamide and Generic drug
Glioblastoma
Glioblastoma, previously known as glioblastoma multiforme (GBM), is the most aggressive and most common type of cancer that originates in the brain, and has a very poor prognosis for survival. Initial signs and symptoms of glioblastoma are nonspecific. They may include headaches, personality changes, nausea, and symptoms similar to those of a stroke.
See Loperamide and Glioblastoma
Goethe University Frankfurt
Goethe University Frankfurt (Johann Wolfgang Goethe-Universität Frankfurt am Main) is a public research university located in Frankfurt am Main, Germany.
See Loperamide and Goethe University Frankfurt
Gut (journal)
Gut is a monthly peer-reviewed medical journal on gastroenterology and hepatology.
See Loperamide and Gut (journal)
Heat stroke
Heat stroke or heatstroke, also known as sun-stroke, is a severe heat illness that results in a body temperature greater than, along with red skin, headache, dizziness, and confusion.
See Loperamide and Heat stroke
HIV/AIDS
The human immunodeficiency virus (HIV) is a retrovirus that attacks the immune system.
Hydrate
In chemistry, a hydrate is a substance that contains water or its constituent elements.
Ileostomy
Ileostomy is a stoma (surgical opening) constructed by bringing the end or loop of small intestine (the ileum) out onto the surface of the skin, or the surgical procedure which creates this opening.
Ileus
Ileus is a disruption of the normal propulsive ability of the intestine.
Inflammatory bowel disease
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine, with Crohn's disease and ulcerative colitis (UC) being the principal types.
See Loperamide and Inflammatory bowel disease
Irinotecan
Irinotecan, sold under the brand name Camptosar among others, is an anti-cancer medication used to treat colon cancer and small cell lung cancer. Loperamide and Irinotecan are World Health Organization essential medicines.
Irritable bowel syndrome
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by a group of symptoms that commonly include abdominal pain, abdominal bloating and changes in the consistency of bowel movements.
See Loperamide and Irritable bowel syndrome
Μ-opioid receptor
The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low affinity for dynorphins.
See Loperamide and Μ-opioid receptor
Janssen Pharmaceuticals
Johnson & Johnson Innovative Medicine (formerly Janssen Pharmaceuticals) is a pharmaceutical company headquartered in Beerse, Belgium, and wholly-owned by Johnson & Johnson. Loperamide and Janssen Pharmaceuticals are Janssen Pharmaceutica.
See Loperamide and Janssen Pharmaceuticals
Johnson & Johnson
Johnson & Johnson (J&J) is an American multinational pharmaceutical, biotechnology, and medical technologies corporation headquartered in New Brunswick, New Jersey, and publicly traded on the New York Stock Exchange.
See Loperamide and Johnson & Johnson
Journal of Medicinal Chemistry
The Journal of Medicinal Chemistry is a biweekly peer-reviewed medical journal covering research in medicinal chemistry.
See Loperamide and Journal of Medicinal Chemistry
Ketoconazole
Ketoconazole, sold under the brand name Nizoral among others, is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. Loperamide and Ketoconazole are Belgian inventions, Chloroarenes, drugs developed by Johnson & Johnson and Janssen Pharmaceutica.
See Loperamide and Ketoconazole
Lactone
Lactones are cyclic carboxylic esters.
Liver
The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.
Liver failure
Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology.
See Loperamide and Liver failure
Loperamide/simethicone
Loperamide/simethicone is combination medication sold under the brand name Imodium Multi-Symptom Relief (formerly Imodium A-D Advanced) used to treat diarrhea and gas simultaneously. Loperamide and Loperamide/simethicone are Antidiarrhoeals, mu-opioid receptor agonists and synthetic opioids.
See Loperamide and Loperamide/simethicone
Melting point
The melting point (or, rarely, liquefaction point) of a substance is the temperature at which it changes state from solid to liquid.
See Loperamide and Melting point
Methadone
Methadone, sold under the brand names Dolophine and Methadose among others, is a synthetic opioid agonist used for chronic pain and also for opioid use disorder. Loperamide and Methadone are HERG blocker, mu-opioid receptor agonists, synthetic opioids and World Health Organization essential medicines.
Morphine
Morphine, formerly also called morphia, is an opiate that is found naturally in opium, a dark brown resin produced by drying the latex of opium poppies (Papaver somniferum). Loperamide and Morphine are mu-opioid receptor agonists and World Health Organization essential medicines.
MPTP
MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is an organic compound.
Myenteric plexus
The myenteric plexus (or Auerbach's plexus) provides motor innervation to both layers of the muscular layer of the gut, having both parasympathetic and sympathetic input (although present ganglion cell bodies belong to parasympathetic innervation, fibers from sympathetic innervation also reach the plexus), whereas the submucous plexus provides secretomotor innervation to the mucosa nearest the lumen of the gut.
See Loperamide and Myenteric plexus
National Health Service
The National Health Service (NHS) is the umbrella term for the publicly funded healthcare systems of the United Kingdom, comprising the NHS in England, NHS Scotland and NHS Wales.
See Loperamide and National Health Service
Neurotoxicity
Neurotoxicity is a form of toxicity in which a biological, chemical, or physical agent produces an adverse effect on the structure or function of the central and/or peripheral nervous system.
See Loperamide and Neurotoxicity
Off-label use
Off-label use is the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration.
See Loperamide and Off-label use
Opioid
Opioids are a class of drugs that derive from, or mimic, natural substances found in the opium poppy plant.
Opioid epidemic
The opioid epidemic, also referred to as the opioid crisis, is the rapid increase in the overuse, misuse/abuse, and overdose deaths attributed either in part or in whole to the class of drugs called opiates/opioids since the 1990s.
See Loperamide and Opioid epidemic
Oral administration
| name.
See Loperamide and Oral administration
Orally disintegrating tablet
An orally disintegrating tablet or orally dissolving tablet (ODT) is a drug dosage form available for a limited range of over-the-counter (OTC) and prescription medications.
See Loperamide and Orally disintegrating tablet
Ortho-McNeil Pharmaceutical
The Ortho-McNeil Pharmaceutical was formed from the merger of Ortho Pharmaceutical and McNeil Pharmaceutical in 1993.
See Loperamide and Ortho-McNeil Pharmaceutical
Over-the-counter drug
Over-the-counter (OTC) drugs are medicines sold directly to a consumer without a requirement for a prescription from a healthcare professional, as opposed to prescription drugs, which may be supplied only to consumers possessing a valid prescription.
See Loperamide and Over-the-counter drug
P-glycoprotein
P-glycoprotein 1 (permeability glycoprotein, abbreviated as P-gp or Pgp) also known as multidrug resistance protein 1 (MDR1) or ATP-binding cassette sub-family B member 1 (ABCB1) or cluster of differentiation 243 (CD243) is an important protein of the cell membrane that pumps many foreign substances out of cells.
See Loperamide and P-glycoprotein
Paul Janssen
Paul Adriaan Jan, Baron Janssen (12 September 1926 – 11 November 2003) was a Belgian physician.
See Loperamide and Paul Janssen
Peripheral nervous system
The peripheral nervous system (PNS) is one of two components that make up the nervous system of bilateral animals, with the other part being the central nervous system (CNS).
See Loperamide and Peripheral nervous system
Physical dependence
Physical dependence is a physical condition caused by chronic use of a tolerance-forming drug, in which abrupt or gradual drug withdrawal causes unpleasant physical symptoms.
See Loperamide and Physical dependence
Placebo
A placebo is a substance or treatment which is designed to have no therapeutic value.
Pregnancy
Pregnancy is the time during which one or more offspring develops (gestates) inside a woman's uterus (womb).
Quinidine
Quinidine is a class IA antiarrhythmic agent used to treat heart rhythm disturbances.
Ritonavir
Ritonavir, sold under the brand name Norvir, is an antiretroviral medication used along with other medications to treat HIV/AIDS. Loperamide and Ritonavir are World Health Organization essential medicines.
Salmonella
Salmonella is a genus of rod-shaped (bacillus) gram-negative bacteria of the family Enterobacteriaceae.
Saquinavir
Saquinavir, sold under the brand name Invirase among others, is an antiretroviral medication used together with other medications to treat or prevent HIV/AIDS.
Short bowel syndrome
Short bowel syndrome (SBS, or simply short gut) is a rare malabsorption disorder caused by a lack of functional small intestine.
See Loperamide and Short bowel syndrome
Smooth muscle
Smooth (soft) muscle is one of the three major types of vertebrate muscle tissue, the other being skeletal and cardiac muscle.
See Loperamide and Smooth muscle
Stevens–Johnson syndrome
Stevens–Johnson syndrome (SJS) is a type of severe skin reaction.
See Loperamide and Stevens–Johnson syndrome
Teratology
Teratology is the study of abnormalities of physiological development in organisms during their life span.
Toxic epidermal necrolysis
Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a type of severe skin reaction.
See Loperamide and Toxic epidermal necrolysis
Toxic megacolon
Toxic megacolon is an acute form of colonic distension.
See Loperamide and Toxic megacolon
Travelers' diarrhea
Travelers' diarrhea (TD) is a stomach and intestinal infection.
See Loperamide and Travelers' diarrhea
Ulcerative colitis
Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease.
See Loperamide and Ulcerative colitis
United Nations
The United Nations (UN) is a diplomatic and political international organization whose stated purposes are to maintain international peace and security, develop friendly relations among nations, achieve international cooperation, and serve as a centre for harmonizing the actions of nations.
See Loperamide and United Nations
Urinary retention
Urinary retention is an inability to completely empty the bladder.
See Loperamide and Urinary retention
WHO Model List of Essential Medicines
The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system. Loperamide and WHO Model List of Essential Medicines are World Health Organization essential medicines.
See Loperamide and WHO Model List of Essential Medicines
World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health.
See Loperamide and World Health Organization
Zydis
Zydis is a technology used to manufacture orally disintegrating tablets developed by R.P. Scherer Corporation.
See also
Antidiarrhoeals
- Albumin tannate
- Antidiarrheal
- Antimotility agent
- Antipropulsive
- Atropine/diphenoxylate
- Bismuth subsalicylate
- Casokefamide
- Chiococca alba
- Codeine
- Crofelemer
- Difenoxin
- Diphenoxylate
- Eluxadoline
- Enkephalinase inhibitor
- Fidaxomicin
- Kaopectate
- Laudanum
- Loperamide
- Loperamide/simethicone
- Mitragyna speciosa
- Motofen
- Nufenoxole
- Palygorskite
- Paregoric
- Racecadotril
- Seirogan
- Somatostatin
- Thiorphan
- Tolevamer
- Zythum
Butyramides
- Amikacin
- Aspartame
- Butyramide
- Butyrylnorfentanyl
- Cilostamide
- Fenpiverinium
- Levetiracetam
- Loperamide
- Mezigdomide
- Sacubitril
- Seletracetam
- Tyropanoic acid
HERG blocker
- Astemizole
- Chloroquine
- Cisapride
- Droperidol
- E-4031
- Fentanyl
- Grepafloxacin
- Hydroxychloroquine
- Ibogaine
- Levacetylmethadol
- Lidoflazine
- Loperamide
- Methadone
- Noribogaine
- Sertindole
- Sildenafil
- Terfenadine
- Vardenafil
- Voacangine
References
[1] https://en.wikipedia.org/wiki/Loperamide
Also known as ATC code A07DA03, ATCvet code QA07DA03, Apo-Loperamide, C29H33ClN2O2, Diarr-Eze, Dimor, Immodium, Imodium, Imodium A-D, Imodium A-D Caplets, Imodium AD, Ioperamide, Kaopectate II, Loperacap, Loperamid, Loperamida, Loperamide HCI, Loperamide Hydrochloride, Loperamide hcl, Loperamidum, Lopex, Maalox Anti-Diarrheal, Norimode, Nu-Loperamide, PMS-Loperamide, Pepto Diarrhea Control, R 18 553, R 18-553, R 18553, R-18 553, R-18-553, R-18553, R18 553, R18-553, R18553, Rho-Loperamide, Travello, Vaprino.
, Μ-opioid receptor, Janssen Pharmaceuticals, Johnson & Johnson, Journal of Medicinal Chemistry, Ketoconazole, Lactone, Liver, Liver failure, Loperamide/simethicone, Melting point, Methadone, Morphine, MPTP, Myenteric plexus, National Health Service, Neurotoxicity, Off-label use, Opioid, Opioid epidemic, Oral administration, Orally disintegrating tablet, Ortho-McNeil Pharmaceutical, Over-the-counter drug, P-glycoprotein, Paul Janssen, Peripheral nervous system, Physical dependence, Placebo, Pregnancy, Quinidine, Ritonavir, Salmonella, Saquinavir, Short bowel syndrome, Smooth muscle, Stevens–Johnson syndrome, Teratology, Toxic epidermal necrolysis, Toxic megacolon, Travelers' diarrhea, Ulcerative colitis, United Nations, Urinary retention, WHO Model List of Essential Medicines, World Health Organization, Zydis.