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MIBE, the Glossary

Index MIBE

MIBE is a synthetic, nonsteroidal antiestrogen that acts as a dual antagonist of the ERα and the GPER.[1]

Table of Contents

  1. 14 relations: Antiestrogen, Breast cancer, Cell (biology), Cell proliferation, Chemical synthesis, Estradiol, Estrogen receptor alpha, Fulvestrant, GPER, MCF-7, Nonsteroidal, Organic compound, Receptor antagonist, Tamoxifen.

  2. Antiestrogens
  3. GPER antagonists
  4. Indole ethers at the benzene ring

Antiestrogen

Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body. MIBE and Antiestrogen are antiestrogens.

See MIBE and Antiestrogen

Breast cancer

Breast cancer is a cancer that develops from breast tissue.

See MIBE and Breast cancer

Cell (biology)

The cell is the basic structural and functional unit of all forms of life.

See MIBE and Cell (biology)

Cell proliferation

Cell proliferation is the process by which a cell grows and divides to produce two daughter cells.

See MIBE and Cell proliferation

Chemical synthesis

Chemical synthesis (chemical combination) is the artificial execution of chemical reactions to obtain one or several products.

See MIBE and Chemical synthesis

Estradiol

Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone.

See MIBE and Estradiol

Estrogen receptor alpha

Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor (mainly found as a chromatin-binding protein) that is activated by the sex hormone estrogen.

See MIBE and Estrogen receptor alpha

Fulvestrant

Fulvestrant, sold under the brand name Faslodex among others, is an antiestrogenic medication used to treat hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women with disease progression as well as HR-positive, HER2-negative advanced breast cancer in combination with abemaciclib or palbociclib in women with disease progression after endocrine therapy. MIBE and Fulvestrant are antiestrogens.

See MIBE and Fulvestrant

GPER

G protein-coupled estrogen receptor 1 (GPER), also known as G protein-coupled receptor 30 (GPR30), is a protein that in humans is encoded by the GPER gene.

See MIBE and GPER

MCF-7

MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old White woman.

See MIBE and MCF-7

Nonsteroidal

A nonsteroidal compound is a drug that is not a steroid nor a steroid derivative.

See MIBE and Nonsteroidal

Organic compound

Some chemical authorities define an organic compound as a chemical compound that contains a carbon–hydrogen or carbon–carbon bond; others consider an organic compound to be any chemical compound that contains carbon.

See MIBE and Organic compound

Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

See MIBE and Receptor antagonist

Tamoxifen

Tamoxifen, sold under the brand name Nolvadex among others, is a selective estrogen receptor modulator used to prevent breast cancer in women and men.

See MIBE and Tamoxifen

See also

Antiestrogens

GPER antagonists

Indole ethers at the benzene ring

References

[1] https://en.wikipedia.org/wiki/MIBE