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Messenger RNA, the Glossary

Index Messenger RNA

In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of synthesizing a protein.[1]

Table of Contents

  1. 149 relations: Activity-regulated cytoskeleton-associated protein, Adaptive immune system, Adenine, Alfred Hershey, Alternative splicing, Amino acid, Animal, Archaea, Arthur Pardee, AU-rich element, Axon, Bacteria, Barley yellow dwarf, Biochemistry, Breast cancer, C-rich stability element, California Institute of Technology, Cap binding complex, Capping enzyme, Cas9, Catalysis, Cell membrane, Cell nucleus, Central dogma of molecular biology, COVID-19 pandemic, CRISPR gene editing, Cytoplasm, Cytoskeleton, DCP2, Decapping complex, Dendrite, Dicer, Directionality (molecular biology), DNA, Drew Weissman, EIF4E, EIF4G, Endonuclease, Endoplasmic reticulum, Enzyme, Escherichia coli, Eukaryote, Eukaryotic initiation factor, Eukaryotic small ribosomal subunit (40S), Eukaryotic translation elongation factor 1 alpha 1, Exon, Exonic splicing enhancer, Exonic splicing silencer, Exonuclease, Exosome complex, ... Expand index (99 more) »

Activity-regulated cytoskeleton-associated protein

Activity-regulated cytoskeleton-associated protein is a plasticity protein that in humans is encoded by the ARC gene.

See Messenger RNA and Activity-regulated cytoskeleton-associated protein

Adaptive immune system

The adaptive immune system, also known as the acquired immune system, or specific immune system is a subsystem of the immune system that is composed of specialized, systemic cells and processes that eliminate pathogens or prevent their growth.

See Messenger RNA and Adaptive immune system

Adenine

Adenine (symbol A or Ade) is a purine nucleobase.

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Alfred Hershey

Alfred Day Hershey (December 4, 1908 – May 22, 1997) was an American Nobel Prize–winning bacteriologist and geneticist.

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Alternative splicing

Alternative splicing, or alternative RNA splicing, or differential splicing, is an alternative splicing process during gene expression that allows a single gene to produce different splice variants. Messenger RNA and alternative splicing are gene expression, RNA splicing and Spliceosome.

See Messenger RNA and Alternative splicing

Amino acid

Amino acids are organic compounds that contain both amino and carboxylic acid functional groups.

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Animal

Animals are multicellular, eukaryotic organisms in the biological kingdom Animalia.

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Archaea

Archaea (archaeon) is a domain of single-celled organisms.

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Arthur Pardee

Arthur Beck Pardee (July 13, 1921 – February 24, 2019) was an American biochemist.

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AU-rich element

Adenylate-uridylate-rich elements (AU-rich elements; AREs) are found in the 3' untranslated region (UTR) of many messenger RNAs (mRNAs) that code for proto-oncogenes, nuclear transcription factors, and cytokines. Messenger RNA and aU-rich element are gene expression and RNA.

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Axon

An axon (from Greek ἄξων áxōn, axis) or nerve fiber (or nerve fibre: see spelling differences) is a long, slender projection of a nerve cell, or neuron, in vertebrates, that typically conducts electrical impulses known as action potentials away from the nerve cell body.

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Bacteria

Bacteria (bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell.

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Barley yellow dwarf

Barley yellow dwarf (BYD) is a plant disease caused by the barley yellow dwarf virus (BYDV), and is the most widely distributed viral disease of cereals.

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Biochemistry

Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms.

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Breast cancer

Breast cancer is a cancer that develops from breast tissue.

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C-rich stability element

The C-rich Not M, -ND stability element is a short part of a gene sequence important for the proper synthesis of globin and several other human proteins.

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California Institute of Technology

The California Institute of Technology (branded as Caltech) is a private research university in Pasadena, California.

See Messenger RNA and California Institute of Technology

Cap binding complex

The 5' cap of eukaryotic messenger RNA is bound at all times by various cap-binding complexes (CBCs). Messenger RNA and cap binding complex are RNA.

See Messenger RNA and Cap binding complex

Capping enzyme

A capping enzyme (CE) is an enzyme that catalyzes the attachment of the 5' cap to messenger RNA molecules that are in the process of being synthesized in the cell nucleus during the first stages of gene expression. Messenger RNA and capping enzyme are gene expression.

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Cas9

Cas9 (CRISPR associated protein 9, formerly called Cas5, Csn1, or Csx12) is a 160 kilodalton protein which plays a vital role in the immunological defense of certain bacteria against DNA viruses and plasmids, and is heavily utilized in genetic engineering applications.

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Catalysis

Catalysis is the increase in rate of a chemical reaction due to an added substance known as a catalyst.

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Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of a cell from the outside environment (the extracellular space).

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Cell nucleus

The cell nucleus (nuclei) is a membrane-bound organelle found in eukaryotic cells.

See Messenger RNA and Cell nucleus

Central dogma of molecular biology

The central dogma of molecular biology deals with the flow of genetic information within a biological system. Messenger RNA and central dogma of molecular biology are molecular genetics.

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COVID-19 pandemic

The COVID-19 pandemic (also known as the coronavirus pandemic), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began with an outbreak of COVID-19 in Wuhan, China, in December 2019.

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CRISPR gene editing

CRISPR gene editing (CRISPR, pronounced "crisper", refers to "clustered regularly interspaced short palindromic repeats") is a genetic engineering technique in molecular biology by which the genomes of living organisms may be modified.

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Cytoplasm

In cell biology, the cytoplasm describes all material within a eukaryotic cell, enclosed by the cell membrane, except for the cell nucleus.

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Cytoskeleton

The cytoskeleton is a complex, dynamic network of interlinking protein filaments present in the cytoplasm of all cells, including those of bacteria and archaea.

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DCP2

mRNA-decapping enzyme 2 is a protein that in humans is encoded by the DCP2 gene.

See Messenger RNA and DCP2

Decapping complex

The mRNA decapping complex is a protein complex in eukaryotic cells responsible for removal of the 5' cap. Messenger RNA and decapping complex are RNA.

See Messenger RNA and Decapping complex

Dendrite

A dendrite (from Greek δένδρον déndron, "tree") or dendron is a branched protoplasmic extension of a nerve cell that propagates the electrochemical stimulation received from other neural cells to the cell body, or soma, of the neuron from which the dendrites project.

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Dicer

Dicer, also known as endoribonuclease Dicer or helicase with RNase motif, is an enzyme that in humans is encoded by the gene.

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Directionality (molecular biology)

Directionality, in molecular biology and biochemistry, is the end-to-end chemical orientation of a single strand of nucleic acid. Messenger RNA and Directionality (molecular biology) are molecular genetics and RNA.

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DNA

Deoxyribonucleic acid (DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix.

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Drew Weissman

Drew Weissman (born September 7, 1959) is an American physician and immunologist known for his contributions to RNA biology.

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EIF4E

Eukaryotic translation initiation factor 4E, also known as eIF4E, is a protein that in humans is encoded by the EIF4E gene.

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EIF4G

Eukaryotic translation initiation factor 4 G (eIF4G) is a protein involved in eukaryotic translation initiation and is a component of the eIF4F cap-binding complex.

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Endonuclease

In molecular biology, endonucleases are enzymes that cleave the phosphodiester bond within a polynucleotide chain (namely DNA or RNA).

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Endoplasmic reticulum

The endoplasmic reticulum (ER) is a part of a transportation system of the eukaryotic cell, and has many other important functions such as protein folding.

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Enzyme

Enzymes are proteins that act as biological catalysts by accelerating chemical reactions.

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Escherichia coli

Escherichia coliWells, J. C. (2000) Longman Pronunciation Dictionary.

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Eukaryote

The eukaryotes constitute the domain of Eukarya or Eukaryota, organisms whose cells have a membrane-bound nucleus.

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Eukaryotic initiation factor

Eukaryotic initiation factors (eIFs) are proteins or protein complexes involved in the initiation phase of eukaryotic translation. Messenger RNA and eukaryotic initiation factor are gene expression.

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Eukaryotic small ribosomal subunit (40S)

The eukaryotic small ribosomal subunit (40S) is the smaller subunit of the eukaryotic 80S ribosomes, with the other major component being the large ribosomal subunit (60S).

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Eukaryotic translation elongation factor 1 alpha 1

Elongation factor 1-alpha 1 (eEF1a1) is a translation elongation protein, expressed across eukaryotes.

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Exon

An exon is any part of a gene that will form a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing. Messenger RNA and exon are RNA splicing and Spliceosome.

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Exonic splicing enhancer

In molecular biology, an exonic splicing enhancer (ESE) is a DNA sequence motif consisting of 6 bases within an exon that directs, or enhances, accurate splicing of heterogeneous nuclear RNA (hnRNA) or pre-mRNA into messenger RNA (mRNA).

See Messenger RNA and Exonic splicing enhancer

Exonic splicing silencer

An exonic splicing silencer (ESS) is a short region (usually 4-18 nucleotides) of an exon and is a cis-regulatory element.

See Messenger RNA and Exonic splicing silencer

Exonuclease

Exonucleases are enzymes that work by cleaving nucleotides one at a time from the end (exo) of a polynucleotide chain.

See Messenger RNA and Exonuclease

Exosome complex

The exosome complex (or PM/Scl complex, often just called the exosome) is a multi-protein intracellular complex capable of degrading various types of RNA (ribonucleic acid) molecules. Messenger RNA and exosome complex are RNA.

See Messenger RNA and Exosome complex

Extension Poly(A) Test

The extension Poly(A) Test (ePAT) describes a method to determine the poly(A) tail lengths of mRNA molecules.

See Messenger RNA and Extension Poly(A) Test

Five prime untranslated region

The 5′ untranslated region (also known as 5′ UTR, leader sequence, transcript leader, or leader RNA) is the region of a messenger RNA (mRNA) that is directly upstream from the initiation codon. Messenger RNA and Five prime untranslated region are gene expression and RNA.

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Five-prime cap

In molecular biology, the five-prime cap (5′ cap) is a specially altered nucleotide on the 5′ end of some primary transcripts such as precursor messenger RNA.

See Messenger RNA and Five-prime cap

François Jacob

François Jacob (17 June 1920 – 19 April 2013) was a French biologist who, together with Jacques Monod, originated the idea that control of enzyme levels in all cells occurs through regulation of transcription.

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Francis Crick

Francis Harry Compton Crick (8 June 1916 – 28 July 2004) was an English molecular biologist, biophysicist, and neuroscientist.

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Gene

In biology, the word gene has two meanings.

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GeneCalling

In the field of genomics, GeneCalling is an open-platform mRNA transcriptional profiling technique. Messenger RNA and GeneCalling are gene expression.

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Genetic code

The genetic code is the set of rules used by living cells to translate information encoded within genetic material (DNA or RNA sequences of nucleotide triplets, or codons) into proteins. Messenger RNA and genetic code are gene expression and molecular genetics.

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Harvard University

Harvard University is a private Ivy League research university in Cambridge, Massachusetts.

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Immune system

The immune system is a network of biological systems that protects an organism from diseases.

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Intron

An intron is any nucleotide sequence within a gene that is not expressed or operative in the final RNA product. Messenger RNA and intron are gene expression, RNA splicing and Spliceosome.

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Jacques Monod

Jacques Lucien Monod (9 February 1910 – 31 May 1976) was a French biochemist who won the Nobel Prize in Physiology or Medicine in 1965, sharing it with François Jacob and André Lwoff "for their discoveries concerning genetic control of enzyme and virus synthesis".

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James Watson

James Dewey Watson (born April 6, 1928) is an American molecular biologist, geneticist, and zoologist.

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Journal of Molecular Biology

The Journal of Molecular Biology is a biweekly peer-reviewed scientific journal covering all aspects of molecular biology.

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Karen Lillycrop

Karen Ann Lillycrop is a British geneticist.

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Katalin Karikó

Katalin "Kati" Karikó (Karikó Katalin,; born 17 January 1955) is a Hungarian-American biochemist who specializes in ribonucleic acid (RNA)-mediated mechanisms, particularly in vitro-transcribed messenger RNA (mRNA) for protein replacement therapy.

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King's College, Cambridge

King's College, formally The King's College of Our Lady and Saint Nicholas in Cambridge, is a constituent college of the University of Cambridge.

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Leaky scanning

Leaky scanning is a mechanism used during the initiation phase of eukaryotic translation that enables regulation of gene expression.

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Martha Chase

Martha Cowles Chase (November 30, 1927 – August 8, 2003), also known as Martha C. Epstein, was an American geneticist who in 1952, with Alfred Hershey, experimentally helped to confirm that DNA rather than protein is the genetic material of life.

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Matthew Meselson

Matthew Stanley Meselson (born May 24, 1930) is a geneticist and molecular biologist currently at Harvard University, known for his demonstration, with Franklin Stahl, of semi-conservative DNA replication.

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Mature messenger RNA

Mature messenger RNA, often abbreviated as mature mRNA is a eukaryotic RNA transcript that has been spliced and processed and is ready for translation in the course of protein synthesis. Messenger RNA and mature messenger RNA are gene expression and RNA.

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Messenger RNP

Messenger RNP (messenger ribonucleoprotein) is mRNA with bound proteins. Messenger RNA and Messenger RNP are RNA.

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MicroRNA

MicroRNA (miRNA) are small, single-stranded, non-coding RNA molecules containing 21 to 23 nucleotides. Messenger RNA and MicroRNA are gene expression and RNA.

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Missense mRNA

Missense mRNA is a messenger RNA bearing one or more mutated codons that yield polypeptides with an amino acid sequence different from the wild-type or naturally occurring polypeptide. Messenger RNA and Missense mRNA are RNA.

See Messenger RNA and Missense mRNA

Moderna COVID-19 vaccine

The Moderna COVID19 vaccine, sold under the brand name Spikevax, is a COVID-19 vaccine developed by the American company Moderna, the United States National Institute of Allergy and Infectious Diseases (NIAID), and the Biomedical Advanced Research and Development Authority (BARDA).

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Molecular biology

Molecular biology is a branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions.

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Molecule

A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion.

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Motor protein

Motor proteins are a class of molecular motors that can move along the cytoskeleton of cells.

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MRNA display

mRNA display is a display technique used for in vitro protein, and/or peptide evolution to create molecules that can bind to a desired target.

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MRNA surveillance

mRNA surveillance mechanisms are pathways utilized by organisms to ensure fidelity and quality of messenger RNA (mRNA) molecules. Messenger RNA and MRNA surveillance are molecular genetics and RNA.

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Nature (journal)

Nature is a British weekly scientific journal founded and based in London, England.

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Nature Reviews Drug Discovery

Nature Reviews Drug Discovery is a monthly peer-reviewed review journal published by Nature Portfolio.

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Neurite

A neurite or neuronal process refers to any projection from the cell body of a neuron.

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Neuron

A neuron, neurone, or nerve cell is an excitable cell that fires electric signals called action potentials across a neural network in the nervous system.

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NMDA receptor

The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca2+ ion channel found in neurons.

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Nobel Prize in Physiology or Medicine

The Nobel Prize in Physiology or Medicine (Nobelpriset i fysiologi eller medicin) is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine.

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Non-stop decay

Non-stop decay (NSD) is a cellular mechanism of mRNA surveillance to detect mRNA molecules lacking a stop codon and prevent these mRNAs from translation. Messenger RNA and Non-stop decay are gene expression.

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Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that exists in all eukaryotes. Messenger RNA and Nonsense-mediated decay are gene expression.

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Nuclear pore

A nuclear pore is a channel as part of the nuclear pore complex (NPC), a large protein complex found in the nuclear envelope of eukaryotic cells.

See Messenger RNA and Nuclear pore

Nucleic acid sequence

A nucleic acid sequence is a succession of bases within the nucleotides forming alleles within a DNA (using GACT) or RNA (GACU) molecule. Messenger RNA and nucleic acid sequence are RNA.

See Messenger RNA and Nucleic acid sequence

Nucleoside-modified messenger RNA

A nucleoside-modified messenger RNA (modRNA) is a synthetic messenger RNA (mRNA) in which some nucleosides are replaced by other naturally modified nucleosides or by synthetic nucleoside analogues. Messenger RNA and nucleoside-modified messenger RNA are life sciences industry, molecular genetics and RNA.

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Nucleotide

Nucleotides are organic molecules composed of a nitrogenous base, a pentose sugar and a phosphate.

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Open reading frame

In molecular biology, reading frames are defined as spans of DNA sequence between the start and stop codons. Messenger RNA and Open reading frame are molecular genetics.

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Operon

In genetics, an operon is a functioning unit of DNA containing a cluster of genes under the control of a single promoter. Messenger RNA and operon are gene expression.

See Messenger RNA and Operon

Outron

An outron is a nucleotide sequence at the 5' end of the primary transcript of a gene that is removed by a special form of RNA splicing during maturation of the final RNA product. Messenger RNA and outron are gene expression, RNA splicing and Spliceosome.

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P-bodies

In cellular biology, P-bodies, or processing bodies, are distinct foci formed by phase separation within the cytoplasm of a eukaryotic cell consisting of many enzymes involved in mRNA turnover.

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Pfizer–BioNTech COVID-19 vaccine

The Pfizer–BioNTech COVID-19 vaccine, sold under the brand name Comirnaty, is an mRNA-based COVID-19 vaccine developed by the German biotechnology company BioNTech. For its development, BioNTech collaborated with the American company Pfizer to carry out clinical trials, logistics, and manufacturing.

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Phosphorylation

In biochemistry, phosphorylation is the attachment of a phosphate group to a molecule or an ion.

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Piwi-interacting RNA

Piwi-interacting RNA (piRNA) is the largest class of small non-coding RNA molecules expressed in animal cells. Messenger RNA and Piwi-interacting RNA are RNA.

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Poliovirus

Poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species Enterovirus C, in the family of Picornaviridae.

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Poly(A)-binding protein

Poly(A)-binding protein (PAB or PABP) is an RNA-binding protein which triggers the binding of eukaryotic initiation factor 4 complex (eIF4G) directly to the poly(A) tail of mRNA which is 200-250 nucleotides long.

See Messenger RNA and Poly(A)-binding protein

Polyadenylation

Polyadenylation is the addition of a poly(A) tail to an RNA transcript, typically a messenger RNA (mRNA). Messenger RNA and Polyadenylation are gene expression.

See Messenger RNA and Polyadenylation

Polynucleotide adenylyltransferase

In enzymology, a polynucleotide adenylyltransferase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are ATP and RNA, whereas its two products are pyrophosphate and RNA with an extra adenosine nucleotide at its 3' end.

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Post-transcriptional modification

Transcriptional modification or co-transcriptional modification is a set of biological processes common to most eukaryotic cells by which an RNA primary transcript is chemically altered following transcription from a gene to produce a mature, functional RNA molecule that can then leave the nucleus and perform any of a variety of different functions in the cell. Messenger RNA and Post-transcriptional modification are gene expression and RNA.

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Primary transcript

A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. Messenger RNA and primary transcript are RNA.

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Prokaryote

A prokaryote (less commonly spelled procaryote) is a single-cell organism whose cell lacks a nucleus and other membrane-bound organelles.

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Prokaryotic mRNA degradation

Prokaryotic messenger RNA (mRNA) degradation, also called prokaryotic mRNA decay, is an important part of gene regulation in prokaryotes.. Messenger RNA and prokaryotic mRNA degradation are RNA.

See Messenger RNA and Prokaryotic mRNA degradation

In genetics, a promoter is a sequence of DNA to which proteins bind to initiate transcription of a single RNA transcript from the DNA downstream of the promoter. Messenger RNA and promoter (genetics) are gene expression.

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Protein

Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues.

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Protein biosynthesis

Protein biosynthesis (or protein synthesis) is a core biological process, occurring inside cells, balancing the loss of cellular proteins (via degradation or export) through the production of new proteins. Messenger RNA and protein biosynthesis are gene expression.

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Protein c-Fos

Protein c-Fos is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos.

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Protein primary structure

Protein primary structure is the linear sequence of amino acids in a peptide or protein.

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Protein secondary structure

Protein secondary structure is the local spatial conformation of the polypeptide backbone excluding the side chains.

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Ribonuclease

Ribonuclease (commonly abbreviated RNase) is a type of nuclease that catalyzes the degradation of RNA into smaller components.

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Ribonuclease III

Ribonuclease III (RNase III or RNase C)(BRENDA) is a type of ribonuclease that recognizes dsRNA and cleaves it at specific targeted locations to transform them into mature RNAs. Messenger RNA and ribonuclease III are RNA.

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Ribonucleotide

In biochemistry, a ribonucleotide is a nucleotide containing ribose as its pentose component. Messenger RNA and ribonucleotide are RNA.

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Ribosomal frameshift

Ribosomal frameshifting, also known as translational frameshifting or translational recoding, is a biological phenomenon that occurs during translation that results in the production of multiple, unique proteins from a single mRNA. Messenger RNA and Ribosomal frameshift are gene expression and RNA.

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Ribosomal RNA

Ribosomal ribonucleic acid (rRNA) is a type of non-coding RNA which is the primary component of ribosomes, essential to all cells. Messenger RNA and Ribosomal RNA are RNA.

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Ribosome

Ribosomes are macromolecular machines, found within all cells, that perform biological protein synthesis (messenger RNA translation).

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Riboswitch

In molecular biology, a riboswitch is a regulatory segment of a messenger RNA molecule that binds a small molecule, resulting in a change in production of the proteins encoded by the mRNA. Messenger RNA and riboswitch are RNA.

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RNA

Ribonucleic acid (RNA) is a polymeric molecule that is essential for most biological functions, either by performing the function itself (non-coding RNA) or by forming a template for the production of proteins (messenger RNA). Messenger RNA and RNA are RNA splicing.

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RNA editing

RNA editing (also RNA modification) is a molecular process through which some cells can make discrete changes to specific nucleotide sequences within an RNA molecule after it has been generated by RNA polymerase. Messenger RNA and RNA editing are gene expression, RNA and RNA splicing.

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RNA polymerase

In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that catalyzes the chemical reactions that synthesize RNA from a DNA template. Messenger RNA and RNA polymerase are gene expression and RNA.

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RNA splicing

RNA splicing is a process in molecular biology where a newly-made precursor messenger RNA (pre-mRNA) transcript is transformed into a mature messenger RNA (mRNA). Messenger RNA and RNA splicing are gene expression, RNA and Spliceosome.

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RNA-induced silencing complex

The RNA-induced silencing complex, or RISC, is a multiprotein complex, specifically a ribonucleoprotein, which functions in gene silencing via a variety of pathways at the transcriptional and translational levels. Messenger RNA and RNA-induced silencing complex are RNA.

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SECIS element

In biology, the SECIS element (SECIS: selenocysteine insertion sequence) is an RNA element around 60 nucleotides in length that adopts a stem-loop structure. Messenger RNA and SECIS element are gene expression.

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Semipermeable membrane

Semipermeable membrane is a type of synthetic or biologic, polymeric membrane that allows certain molecules or ions to pass through it by osmosis.

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Signal recognition particle

The signal recognition particle (SRP) is an abundant, cytosolic, universally conserved ribonucleoprotein (protein-RNA complex) that recognizes and targets specific proteins to the endoplasmic reticulum in eukaryotes and the plasma membrane in prokaryotes.

See Messenger RNA and Signal recognition particle

Small interfering RNA

Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA at first non-coding RNA molecules, typically 20–24 (normally 21) base pairs in length, similar to miRNA, and operating within the RNA interference (RNAi) pathway. Messenger RNA and Small interfering RNA are RNA.

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Small RNA

Small RNA (sRNA) are polymeric RNA molecules that are less than 200 nucleotides in length, and are usually non-coding.

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Soma (biology)

In cellular neuroscience, the soma (somata or somas), perikaryon (perikarya), neurocyton, or cell body is the bulbous, non-process portion of a neuron or other brain cell type, containing the cell nucleus.

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Src family kinase

Src kinase family is a family of non-receptor tyrosine kinases that includes nine members: Src, Yes, Fyn, and Fgr, forming the SrcA subfamily, Lck, Hck, Blk, and Lyn in the SrcB subfamily, and Frk in its own subfamily.

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Start codon

The start codon is the first codon of a messenger RNA (mRNA) transcript translated by a ribosome. Messenger RNA and start codon are molecular genetics.

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Stem cell

In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely to produce more of the same stem cell.

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Stop codon

In molecular biology, a stop codon (or termination codon) is a codon (nucleotide triplet within messenger RNA) that signals the termination of the translation process of the current protein. Messenger RNA and stop codon are gene expression and molecular genetics.

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Sydney Brenner

Sydney Brenner (13 January 1927 – 5 April 2019) was a South African biologist.

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Synapse

In the nervous system, a synapse is a structure that permits a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or to the target effector cell.

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Three prime untranslated region

In molecular genetics, the three prime untranslated region (3′-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon. Messenger RNA and three prime untranslated region are gene expression and RNA.

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Transcription (biology)

Transcription is the process of copying a segment of DNA into RNA. Messenger RNA and Transcription (biology) are gene expression.

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Transcription factor Jun

Transcription factor Jun is a protein that in humans is encoded by the JUN gene.

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Transcriptome

The transcriptome is the set of all RNA transcripts, including coding and non-coding, in an individual or a population of cells. Messenger RNA and transcriptome are gene expression, RNA and RNA splicing.

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Transfer RNA

Transfer RNA (abbreviated tRNA and formerly referred to as sRNA, for soluble RNA) is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides in length (in eukaryotes), that serves as the physical link between the mRNA and the amino acid sequence of proteins. Messenger RNA and Transfer RNA are RNA.

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Translation (biology)

In biology, translation is the process in living cells in which proteins are produced using RNA molecules as templates. Messenger RNA and translation (biology) are gene expression.

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Translational efficiency

In cell biology, translational efficiency or translation efficiency is the rate of mRNA translation into proteins within cells.

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Tunneling nanotube

A tunneling nanotube (TNT) or membrane nanotube is a term that has been applied to cytoskeletal protrusions that extend from the plasma membrane which enable different animal cells to connect over long distances, sometimes over 100 μm between certain types of cells.

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V(D)J recombination

V(D)J recombination (variable–diversity–joining rearrangement) is the mechanism of somatic recombination that occurs only in developing lymphocytes during the early stages of T and B cell maturation.

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Vaccine

A vaccine is a biological preparation that provides active acquired immunity to a particular infectious or malignant disease.

See Messenger RNA and Vaccine

ZBP1

Z-DNA-binding protein 1, also known as DNA-dependent activator of IFN-regulatory factors (DAI) and DLM-1, is a protein that in humans is encoded by the ZBP1 gene.

See Messenger RNA and ZBP1

7-Methylguanosine

7-Methylguanosine (m7G) is a modified purine nucleoside.

See Messenger RNA and 7-Methylguanosine

References

[1] https://en.wikipedia.org/wiki/Messenger_RNA

Also known as Dicistronic, MRNA, MRNA stability, MRNAs, Messenger RNAs, Messenger Ribonucleic Acid, Messenger-RNA, Monocistronic mRNA, Polycisticity, Polycistronic mRNA, Polycistronic message, RNA therapy, Rna, messenger.

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