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Microscopic polyangiitis, the Glossary

Index Microscopic polyangiitis

Microscopic polyangiitis is an autoimmune disease characterized by a systemic, pauci-immune, necrotizing, small-vessel vasculitis without clinical or pathological evidence of granulomatous inflammation.[1]

Table of Contents

  1. 31 relations: Anemia, Anti-neutrophil cytoplasmic antibody, Autoimmune disease, C-reactive protein, Cyclophosphamide, Electromyography, Erythrocyte sedimentation rate, Fatigue, Fever, Glucocorticoid, Granuloma, Granulomatosis with polyangiitis, Hemoptysis, Inflammation, Kidney failure, List of skin conditions, Livedo racemosa, Myeloperoxidase, Neutrophil, P-ANCA, Pauci-immune, Plasmapheresis, Polyarteritis nodosa, Proteinuria, Pulmonary fibrosis, Pulmonary hemorrhage, Purpura, Red blood cell, Rituximab, Sinusitis, Vasculitis.

  2. Systemic connective tissue disorders

Anemia

Anemia or anaemia (British English) is a blood disorder in which the blood has a reduced ability to carry oxygen.

See Microscopic polyangiitis and Anemia

Anti-neutrophil cytoplasmic antibody

Anti-neutrophil cytoplasmic antibodies (ANCAs) are a group of autoantibodies, mainly of the IgG type, against antigens in the cytoplasm of neutrophils (the most common type of white blood cell) and monocytes.

See Microscopic polyangiitis and Anti-neutrophil cytoplasmic antibody

Autoimmune disease

An autoimmune disease is a condition that results from an anomalous response of the adaptive immune system, wherein it mistakenly targets and attacks healthy, functioning parts of the body as if they were foreign organisms.

See Microscopic polyangiitis and Autoimmune disease

C-reactive protein

C-reactive protein (CRP) is an annular (ring-shaped) pentameric protein found in blood plasma, whose circulating concentrations rise in response to inflammation.

See Microscopic polyangiitis and C-reactive protein

Cyclophosphamide

Cyclophosphamide (CP), also known as cytophosphane among other names, is a medication used as chemotherapy and to suppress the immune system.

See Microscopic polyangiitis and Cyclophosphamide

Electromyography

Electromyography (EMG) is a technique for evaluating and recording the electrical activity produced by skeletal muscles.

See Microscopic polyangiitis and Electromyography

Erythrocyte sedimentation rate

The erythrocyte sedimentation rate (ESR or sed rate) is the rate at which red blood cells in anticoagulated whole blood descend in a standardized tube over a period of one hour.

See Microscopic polyangiitis and Erythrocyte sedimentation rate

Fatigue

Fatigue describes a state of tiredness (which is not sleepiness), exhaustion or loss of energy.

See Microscopic polyangiitis and Fatigue

Fever

Fever or pyrexia in humans is a body temperature above the normal range due to an increase in the body's temperature set point in the hypothalamus.

See Microscopic polyangiitis and Fever

Glucocorticoid

Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones.

See Microscopic polyangiitis and Glucocorticoid

Granuloma

A granuloma is an aggregation of macrophages (along with other cells) that forms in response to chronic inflammation.

See Microscopic polyangiitis and Granuloma

Granulomatosis with polyangiitis

Granulomatosis with polyangiitis (GPA), previously known as Wegener's granulomatosis (WG), after the German physician Friedrich Wegener, is a rare long-term systemic disorder that involves the formation of granulomas and inflammation of blood vessels (vasculitis). Microscopic polyangiitis and granulomatosis with polyangiitis are steroid-responsive inflammatory conditions, systemic connective tissue disorders and Vascular-related cutaneous conditions.

See Microscopic polyangiitis and Granulomatosis with polyangiitis

Hemoptysis

Hemoptysis or haemoptysis is the discharge of blood or blood-stained mucus through the mouth coming from the bronchi, larynx, trachea, or lungs.

See Microscopic polyangiitis and Hemoptysis

Inflammation

Inflammation (from inflammatio) is part of the biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants.

See Microscopic polyangiitis and Inflammation

Kidney failure

Kidney failure, also known as end-stage renal disease (ESRD), is a medical condition in which the kidneys can no longer adequately filter waste products from the blood, functioning at less than 15% of normal levels. Kidney failure is classified as either acute kidney failure, which develops rapidly and may resolve; and chronic kidney failure, which develops slowly and can often be irreversible.

See Microscopic polyangiitis and Kidney failure

List of skin conditions

Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands.

See Microscopic polyangiitis and List of skin conditions

Livedo racemosa

Livedo racemosa is a skin condition with persistent red or violet discoloration, characterised by a broken, branched, discontinuous and irregular pattern. Microscopic polyangiitis and Livedo racemosa are Vascular-related cutaneous conditions.

See Microscopic polyangiitis and Livedo racemosa

Myeloperoxidase

Myeloperoxidase (MPO) is a peroxidase enzyme that in humans is encoded by the MPO gene on chromosome 17.

See Microscopic polyangiitis and Myeloperoxidase

Neutrophil

Neutrophils (also known as neutrocytes, heterophils or polymorphonuclear leukocytes) are a type of white blood cell.

See Microscopic polyangiitis and Neutrophil

P-ANCA

p-ANCA, or MPO-ANCA, or perinuclear anti-neutrophil cytoplasmic antibodies, are antibodies that stain the material around the nucleus of a neutrophil.

See Microscopic polyangiitis and P-ANCA

Pauci-immune

Pauci-immune (pauci- Latin: few, little) vasculitis is a form of vasculitis that is associated with minimal evidence of hypersensitivity upon immunofluorescent staining for IgG. Microscopic polyangiitis and Pauci-immune are Vascular-related cutaneous conditions.

See Microscopic polyangiitis and Pauci-immune

Plasmapheresis

Plasmapheresis (from the Greek πλάσμα, plasma, something molded, and ἀφαίρεσις aphairesis, taking away) is the removal, treatment, and return or exchange of blood plasma or components thereof from and to the blood circulation.

See Microscopic polyangiitis and Plasmapheresis

Polyarteritis nodosa

Polyarteritis nodosa (PAN) is a systemic necrotizing inflammation of blood vessels (vasculitis) affecting medium-sized muscular arteries, typically involving the arteries of the kidneys and other internal organs but generally sparing the lungs' circulation. Microscopic polyangiitis and Polyarteritis nodosa are steroid-responsive inflammatory conditions, systemic connective tissue disorders and Vascular-related cutaneous conditions.

See Microscopic polyangiitis and Polyarteritis nodosa

Proteinuria

Proteinuria is the presence of excess proteins in the urine.

See Microscopic polyangiitis and Proteinuria

Pulmonary fibrosis

Pulmonary fibrosis is a condition in which the lungs become scarred over time.

See Microscopic polyangiitis and Pulmonary fibrosis

Pulmonary hemorrhage

Pulmonary hemorrhage (or pulmonary haemorrhage) is an acute bleeding from the lung, from the upper respiratory tract and the trachea, and the pulmonary alveoli.

See Microscopic polyangiitis and Pulmonary hemorrhage

Purpura

Purpura is a condition of red or purple discolored spots on the skin that do not blanch on applying pressure.

See Microscopic polyangiitis and Purpura

Red blood cell

Red blood cells (RBCs), referred to as erythrocytes (with -cyte translated as 'cell' in modern usage) in academia and medical publishing, also known as red cells, erythroid cells, and rarely haematids, are the most common type of blood cell and the vertebrate's principal means of delivering oxygen to the body tissues—via blood flow through the circulatory system.

See Microscopic polyangiitis and Red blood cell

Rituximab

Rituximab, sold under the brand name Rituxan among others, is a monoclonal antibody medication used to treat certain autoimmune diseases and types of cancer.

See Microscopic polyangiitis and Rituximab

Sinusitis

Sinusitis, also known as rhinosinusitis, is an inflammation of the mucous membranes that line the sinuses resulting in symptoms that may include thick nasal mucus, a plugged nose, and facial pain.

See Microscopic polyangiitis and Sinusitis

Vasculitis

Vasculitis is a group of disorders that destroy blood vessels by inflammation. Microscopic polyangiitis and Vasculitis are Vascular-related cutaneous conditions.

See Microscopic polyangiitis and Vasculitis

See also

Systemic connective tissue disorders

References

[1] https://en.wikipedia.org/wiki/Microscopic_polyangiitis

Also known as Microscophic polyangiitis, Microscopic polyangitis, Microscopic polyarteritis, Microscopic polyarteritis nodosa, Polyangiitis overlap syndrome.