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OmpA domain, the Glossary

In molecular biology, the OmpA domain is a conserved protein domain with a beta/alpha/beta/alpha-beta(2) structure found in the C-terminal region of many Gram-negative bacterial outer membrane proteins, such as porin-like integral membrane proteins (such as ompA), small lipid-anchored proteins (such as pal), and MotB proton channels.^[1]

22 relations: Bacterial outer membrane, C-terminus, Cell membrane, Cell wall, Conserved sequence, Escherichia coli, Flagellum, Gram-negative bacteria, Integral membrane protein, Ion, Lipid-anchored protein, N-terminus, OmpA-like transmembrane domain, Pathogenesis, Porin (protein), Protein, Protein complex, Protein domain, Protein secondary structure, Proton pump, Receptor (biochemistry), Stator.
Outer membrane proteins

Bacterial outer membrane

The bacterial outer membrane is found in gram-negative bacteria. OmpA domain and bacterial outer membrane are protein families.

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C-terminus

The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, carboxy tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).

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Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of a cell from the outside environment (the extracellular space).

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Cell wall

A cell wall is a structural layer that surrounds some cell types, found immediately outside the cell membrane.

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Conserved sequence

In evolutionary biology, conserved sequences are identical or similar sequences in nucleic acids (DNA and RNA) or proteins across species (orthologous sequences), or within a genome (paralogous sequences), or between donor and receptor taxa (xenologous sequences).

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Escherichia coli

Escherichia coliWells, J. C. (2000) Longman Pronunciation Dictionary.

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Flagellum

A flagellum (flagella) (Latin for 'whip' or 'scourge') is a hairlike appendage that protrudes from certain plant and animal sperm cells, from fungal spores (zoospores), and from a wide range of microorganisms to provide motility.

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Gram-negative bacteria

Gram-negative bacteria are bacteria that unlike gram-positive bacteria do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation.

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Integral membrane protein

An integral, or intrinsic, membrane protein (IMP) is a type of membrane protein that is permanently attached to the biological membrane.

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Ion

An ion is an atom or molecule with a net electrical charge.

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Lipid-anchored protein

Lipid-anchored proteins (also known as lipid-linked proteins) are proteins located on the surface of the cell membrane that are covalently attached to lipids embedded within the cell membrane.

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N-terminus

The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide, referring to the free amine group (-NH2) located at the end of a polypeptide.

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OmpA-like transmembrane domain

OmpA-like transmembrane domain is an evolutionarily conserved domain of bacterial outer membrane proteins. OmpA domain and OmpA-like transmembrane domain are outer membrane proteins.

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Pathogenesis

In pathology, pathogenesis is the process by which a disease or disorder develops.

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Porin (protein)

Porins are beta barrel proteins that cross a cellular membrane and act as a pore, through which molecules can diffuse. OmpA domain and Porin (protein) are outer membrane proteins.

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Protein

Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues.

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Protein complex

A protein complex or multiprotein complex is a group of two or more associated polypeptide chains.

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Protein domain

In molecular biology, a protein domain is a region of a protein's polypeptide chain that is self-stabilizing and that folds independently from the rest. OmpA domain and protein domain are protein families.

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Protein secondary structure

Protein secondary structure is the local spatial conformation of the polypeptide backbone excluding the side chains.

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Proton pump

A proton pump is an integral membrane protein pump that builds up a proton gradient across a biological membrane.

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Receptor (biochemistry)

In biochemistry and pharmacology, receptors are chemical structures, composed of protein, that receive and transduce signals that may be integrated into biological systems.

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Stator

The stator is the stationary part of a rotary system, found in electric generators, electric motors, sirens, mud motors, or biological rotors (such as bacterial flagella or ATP synthase).

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References

[1] https://en.wikipedia.org/wiki/OmpA_domain