Orexin-A, the Glossary
Orexin-A, also known as hypocretin-1, is a naturally occurring neuropeptide and orexin isoform.[1]
Table of Contents
24 relations: Acetylcholine, Cysteine, Disulfide, Dopamine, G protein-coupled receptor, Glucose, Histamine, Lateral hypothalamus, Memory, N-terminus, Narcolepsy, Neuron, Neuropeptide, Norepinephrine, Orexin, Orexin receptor, Peptide, Placebo, Positron emission tomography, Protein isoform, Pyroglutamic acid, Rhesus macaque, Treatment and control groups, University of Manchester.
- Orexin receptor agonists
Acetylcholine
Acetylcholine (ACh) is an organic compound that functions in the brain and body of many types of animals (including humans) as a neurotransmitter.
See Orexin-A and Acetylcholine
Cysteine
Cysteine (symbol Cys or C) is a semiessential proteinogenic amino acid with the formula.
Disulfide
In chemistry, a disulfide (or disulphide in British English) is a compound containing a functional group or the anion.
Dopamine
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells.
G protein-coupled receptor
G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked receptors (GPLR), form a large group of evolutionarily related proteins that are cell surface receptors that detect molecules outside the cell and activate cellular responses.
See Orexin-A and G protein-coupled receptor
Glucose
Glucose is a sugar with the molecular formula.
Histamine
Histamine is an organic nitrogenous compound involved in local immune responses communication, as well as regulating physiological functions in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus.
Lateral hypothalamus
The lateral hypothalamus (LH), also called the lateral hypothalamic area (LHA), contains the primary orexinergic nucleus within the hypothalamus that widely projects throughout the nervous system; this system of neurons mediates an array of cognitive and physical processes, such as promoting feeding behavior and arousal, reducing pain perception, and regulating body temperature, digestive functions, and blood pressure, among many others.
See Orexin-A and Lateral hypothalamus
Memory
Memory is the faculty of the mind by which data or information is encoded, stored, and retrieved when needed.
N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide, referring to the free amine group (-NH2) located at the end of a polypeptide.
Narcolepsy
Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep.
Neuron
A neuron, neurone, or nerve cell is an excitable cell that fires electric signals called action potentials across a neural network in the nervous system.
Neuropeptide
Neuropeptides are chemical messengers made up of small chains of amino acids that are synthesized and released by neurons. Orexin-A and Neuropeptide are neuropeptides.
Norepinephrine
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone, neurotransmitter and neuromodulator.
See Orexin-A and Norepinephrine
Orexin
Orexin, also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. Orexin-A and Orexin are molecular neuroscience, neuropeptides and orexin receptor agonists.
Orexin receptor
The orexin receptor (also referred to as the hypocretin receptor) is a G-protein-coupled receptor that binds the neuropeptide orexin.
See Orexin-A and Orexin receptor
Peptide
Peptides are short chains of amino acids linked by peptide bonds.
Placebo
A placebo is a substance or treatment which is designed to have no therapeutic value.
Positron emission tomography
Positron emission tomography (PET) is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption.
See Orexin-A and Positron emission tomography
Protein isoform
A protein isoform, or "protein variant", is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.
See Orexin-A and Protein isoform
Pyroglutamic acid
Pyroglutamic acid (also known as PCA, 5-oxoproline, pidolic acid) is a ubiquitous but understudied natural amino acid derivative in which the free amino group of glutamic acid or glutamine cyclizes to form a lactam.
See Orexin-A and Pyroglutamic acid
Rhesus macaque
The rhesus macaque (Macaca mulatta), colloquially rhesus monkey, is a species of Old World monkey.
See Orexin-A and Rhesus macaque
Treatment and control groups
In the design of experiments, hypotheses are applied to experimental units in a treatment group.
See Orexin-A and Treatment and control groups
University of Manchester
The University of Manchester is a public research university in Manchester, England.
See Orexin-A and University of Manchester
See also
Orexin receptor agonists
- Danavorexton
- Firazorexton
- Orexin
- Orexin-A
- Suntinorexton
References
[1] https://en.wikipedia.org/wiki/Orexin-A
Also known as Orexin A.