PCDH15, the Glossary
Protocadherin-15 is a protein that in humans is encoded by the PCDH15 gene.[1]
Table of Contents
13 relations: Cadherin, Cadherin cytoplasmic region, Calcium, CDH23, Cell adhesion, Cochlea, Gene, Protein, Retina, Signal peptide, Tip link, Transmembrane domain, Usher syndrome.
Cadherin
Cadherins (named for "calcium-dependent adhesion") are cell adhesion molecules important in forming adherens junctions that let cells adhere to each other.
Cadherin cytoplasmic region
In molecular biology, the cadherin cytoplasmic region is a conserved region found at the C-terminus of cadherin proteins.
See PCDH15 and Cadherin cytoplasmic region
Calcium
Calcium is a chemical element; it has symbol Ca and atomic number 20.
CDH23
Cadherin-23 is a protein that in humans is encoded by the CDH23 gene. PCDH15 and CDH23 are genes on human chromosome 10 and human chromosome 10 gene stubs.
See PCDH15 and CDH23
Cell adhesion
Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface.
Cochlea
The cochlea is the part of the inner ear involved in hearing.
Gene
In biology, the word gene has two meanings.
See PCDH15 and Gene
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues.
Retina
The retina (or retinas) is the innermost, light-sensitive layer of tissue of the eye of most vertebrates and some molluscs.
Signal peptide
A signal peptide (sometimes referred to as signal sequence, targeting signal, localization signal, localization sequence, transit peptide, leader sequence or leader peptide) is a short peptide (usually 16-30 amino acids long) present at the N-terminus (or occasionally nonclassically at the C-terminus or internally) of most newly synthesized proteins that are destined toward the secretory pathway.
Tip link
Tip links are extracellular filaments that connect stereocilia to each other or to the kinocilium in the hair cells of the inner ear.
Transmembrane domain
A transmembrane domain (TMD) is a membrane-spanning protein domain.
See PCDH15 and Transmembrane domain
Usher syndrome
Usher syndrome, also known as Hallgren syndrome, Usher–Hallgren syndrome, retinitis pigmentosa–dysacusis syndrome or dystrophia retinae dysacusis syndrome, is a rare genetic disorder caused by a mutation in any one of at least 11 genes resulting in a combination of hearing loss and visual impairment.
References
[1] https://en.wikipedia.org/wiki/PCDH15
Also known as PCDH15 (gene), Protocadherin 15.