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Protein kinase C, the Glossary

Index Protein kinase C

In cell biology, Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family.[1]

Table of Contents

  1. 173 relations: Acetylcholine, Actinic keratosis, Active site, Adaptive immune system, Adipocyte, Adrenergic agonist, Alzheimer's disease, Amino acid, Angiotensin, Angiotensin II receptor type 1, Arrector pili muscle, Astronaut, Autonomic ganglion, B-cell receptor, Base (chemistry), BCL10, Beta-3 adrenergic receptor, BIM-1, Binding site, Biochemistry, Bladder, Bronchoconstriction, Bronchus, Bryostatin, C1 domain, C2 domain, Calcium, Calpain, CARD-CC family, CARD11, CARD9, Cardiac muscle, Ccdc60, Cell biology, Cell membrane, Central nervous system, Cerebrospinal fluid, Chelerythrine, Choroid plexus, Ciliary muscle, Circulatory system, CLEC7A, Consensus sequence, Crystal structure, Decoy, Diabetic nephropathy, Diglyceride, Ejaculation, Endocrine system, Enzyme, ... Expand index (123 more) »

Acetylcholine

Acetylcholine (ACh) is an organic compound that functions in the brain and body of many types of animals (including humans) as a neurotransmitter.

See Protein kinase C and Acetylcholine

Actinic keratosis

Actinic keratosis (AK), sometimes called solar keratosis or senile keratosis, is a pre-cancerous area of thick, scaly, or crusty skin.

See Protein kinase C and Actinic keratosis

Active site

In biology and biochemistry, the active site is the region of an enzyme where substrate molecules bind and undergo a chemical reaction.

See Protein kinase C and Active site

Adaptive immune system

The adaptive immune system, also known as the acquired immune system, or specific immune system is a subsystem of the immune system that is composed of specialized, systemic cells and processes that eliminate pathogens or prevent their growth.

See Protein kinase C and Adaptive immune system

Adipocyte

Adipocytes, also known as lipocytes and fat cells, are the cells that primarily compose adipose tissue, specialized in storing energy as fat.

See Protein kinase C and Adipocyte

Adrenergic agonist

An adrenergic agonist is a drug that stimulates a response from the adrenergic receptors.

See Protein kinase C and Adrenergic agonist

Alzheimer's disease

Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens, and is the cause of 60–70% of cases of dementia.

See Protein kinase C and Alzheimer's disease

Amino acid

Amino acids are organic compounds that contain both amino and carboxylic acid functional groups.

See Protein kinase C and Amino acid

Angiotensin

Angiotensin is a peptide hormone that causes vasoconstriction and an increase in blood pressure.

See Protein kinase C and Angiotensin

Angiotensin II receptor type 1

Angiotensin II receptor type 1 (AT1) is a Gq/11-coupled G protein-coupled receptor (GPCR) and the best characterized angiotensin receptor.

See Protein kinase C and Angiotensin II receptor type 1

Arrector pili muscle

The arrector pili muscles, also known as hair erector muscles, are small muscles attached to hair follicles in mammals.

See Protein kinase C and Arrector pili muscle

Astronaut

An astronaut (from the Ancient Greek ἄστρον, meaning 'star', and ναύτης, meaning 'sailor') is a person trained, equipped, and deployed by a human spaceflight program to serve as a commander or crew member aboard a spacecraft.

See Protein kinase C and Astronaut

Autonomic ganglion

An autonomic ganglion is a cluster of nerve cell bodies (a ganglion) in the autonomic nervous system.

See Protein kinase C and Autonomic ganglion

B-cell receptor

The B-cell receptor (BCR) is a transmembrane protein on the surface of a B cell.

See Protein kinase C and B-cell receptor

Base (chemistry)

In chemistry, there are three definitions in common use of the word "base": Arrhenius bases, Brønsted bases, and Lewis bases.

See Protein kinase C and Base (chemistry)

BCL10

B-cell lymphoma/leukemia 10 is a protein that in humans is encoded by the BCL10 gene.

See Protein kinase C and BCL10

Beta-3 adrenergic receptor

The beta-3 adrenergic receptor (β3-adrenoceptor), also known as ADRB3, is a beta-adrenergic receptor, and also denotes the human gene encoding it.

See Protein kinase C and Beta-3 adrenergic receptor

BIM-1

BIM-1 (GF 109203X) and the related compounds BIM-2, BIM-3, and BIM-8 are bisindolylmaleimide-based protein kinase C (PKC) inhibitors.

See Protein kinase C and BIM-1

Binding site

In biochemistry and molecular biology, a binding site is a region on a macromolecule such as a protein that binds to another molecule with specificity.

See Protein kinase C and Binding site

Biochemistry

Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms.

See Protein kinase C and Biochemistry

Bladder

The bladder is a hollow organ in humans and other vertebrates that stores urine from the kidneys before disposal by urination.

See Protein kinase C and Bladder

Bronchoconstriction

Bronchoconstriction is the constriction of the airways in the lungs due to the tightening of surrounding smooth muscle, with consequent coughing, wheezing, and shortness of breath.

See Protein kinase C and Bronchoconstriction

Bronchus

A bronchus (bronchi) is a passage or airway in the lower respiratory tract that conducts air into the lungs.

See Protein kinase C and Bronchus

Bryostatin

Bryostatins are a group of macrolide lactones from (bacterial symbionts of) the marine organism Bugula neritina that were first collected and provided to JL Hartwell’s anticancer drug discovery group at the National Cancer Institute (NCI) by Jack Rudloe.

See Protein kinase C and Bryostatin

C1 domain

C1 domain (also known as phorbol esters/diacylglycerol binding domain) binds an important secondary messenger diacylglycerol (DAG), as well as the analogous phorbol esters.

See Protein kinase C and C1 domain

C2 domain

A C2 domain is a protein structural domain involved in targeting proteins to cell membranes.

See Protein kinase C and C2 domain

Calcium

Calcium is a chemical element; it has symbol Ca and atomic number 20.

See Protein kinase C and Calcium

Calpain

A calpain is a protein belonging to the family of calcium-dependent, non-lysosomal cysteine proteases (proteolytic enzymes) expressed ubiquitously in mammals and many other organisms.

See Protein kinase C and Calpain

CARD-CC family

The CARD-CC protein family is defined by an evolutionary conserved "caspase activation and recruitment domain" (CARD) and a coiled-coil (CC) domain.

See Protein kinase C and CARD-CC family

CARD11

Caspase recruitment domain-containing protein 11 also known as CARD-containing MAGUK protein 1 (Carma 1) is a protein in the CARD-CC protein family that in humans is encoded by the CARD11 gene.

See Protein kinase C and CARD11

CARD9

Caspase recruitment domain-containing protein 9 is an adaptor protein of the CARD-CC protein family, which in humans is encoded by the CARD9 gene.

See Protein kinase C and CARD9

Cardiac muscle

Cardiac muscle (also called heart muscle or myocardium) is one of three types of vertebrate muscle tissues, with the other two being skeletal muscle and smooth muscle.

See Protein kinase C and Cardiac muscle

Ccdc60

Coiled-coil domain containing 60 is a protein that in humans is encoded by the CCDC60 gene that is most highly expressed in the trachea, salivary glands, bladder, cervix, and epididymis.

See Protein kinase C and Ccdc60

Cell biology

Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells.

See Protein kinase C and Cell biology

Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of a cell from the outside environment (the extracellular space).

See Protein kinase C and Cell membrane

Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord.

See Protein kinase C and Central nervous system

Cerebrospinal fluid

Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates.

See Protein kinase C and Cerebrospinal fluid

Chelerythrine

Chelerythrine is a benzophenanthridine alkaloid present in the plant Chelidonium majus (greater celandine).

See Protein kinase C and Chelerythrine

Choroid plexus

The choroid plexus, or plica choroidea, is a plexus of cells that arises from the tela choroidea in each of the ventricles of the brain.

See Protein kinase C and Choroid plexus

Ciliary muscle

The ciliary muscle is an intrinsic muscle of the eye formed as a ring of smooth muscleSchachar, Ronald A. (2012). "Anatomy and Physiology." (Chapter 4). in the eye's middle layer, uvea (vascular layer). It controls accommodation for viewing objects at varying distances and regulates the flow of aqueous humor into Schlemm's canal.

See Protein kinase C and Ciliary muscle

Circulatory system

The circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate.

See Protein kinase C and Circulatory system

CLEC7A

C-type lectin domain family 7 member A or Dectin-1 is a protein that in humans is encoded by the CLEC7A gene.

See Protein kinase C and CLEC7A

Consensus sequence

In molecular biology and bioinformatics, the consensus sequence (or canonical sequence) is the calculated sequence of most frequent residues, either nucleotide or amino acid, found at each position in a sequence alignment.

See Protein kinase C and Consensus sequence

Crystal structure

In crystallography, crystal structure is a description of ordered arrangement of atoms, ions, or molecules in a crystalline material.

See Protein kinase C and Crystal structure

Decoy

A decoy (derived from the Dutch de kooi, literally "the cage" or possibly ende kooi, "duck cage") is usually a person, device, or event which resembles what an individual or a group might be looking for, but it is only meant to lure them.

See Protein kinase C and Decoy

Diabetic nephropathy

Diabetic nephropathy, also known as diabetic kidney disease, is the chronic loss of kidney function occurring in those with diabetes mellitus.

See Protein kinase C and Diabetic nephropathy

Diglyceride

A diglyceride, or diacylglycerol (DAG), is a glyceride consisting of two fatty acid chains covalently bonded to a glycerol molecule through ester linkages.

See Protein kinase C and Diglyceride

Ejaculation

Ejaculation is the discharge of semen (the ejaculate; normally containing sperm) through the urethra in men.

See Protein kinase C and Ejaculation

Endocrine system

The endocrine system is a messenger system in an organism comprising feedback loops of hormones that are released by internal glands directly into the circulatory system and that target and regulate distant organs.

See Protein kinase C and Endocrine system

Enzyme

Enzymes are proteins that act as biological catalysts by accelerating chemical reactions.

See Protein kinase C and Enzyme

Ependyma

The ependyma is the thin neuroepithelial (simple columnar ciliated epithelium) lining of the ventricular system of the brain and the central canal of the spinal cord.

See Protein kinase C and Ependyma

Epidermal growth factor receptor

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands.

See Protein kinase C and Epidermal growth factor receptor

Euphorbia peplus

Euphorbia peplus (petty spurge, radium weed, cancer weed, or milkweed), is a species of Euphorbia, native to most of Europe, northern Africa and western Asia, where it typically grows in cultivated arable land, gardens and other disturbed land.

See Protein kinase C and Euphorbia peplus

Excitatory postsynaptic potential

In neuroscience, an excitatory postsynaptic potential (EPSP) is a postsynaptic potential that makes the postsynaptic neuron more likely to fire an action potential.

See Protein kinase C and Excitatory postsynaptic potential

Fungus

A fungus (fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms.

See Protein kinase C and Fungus

G protein-coupled receptor

G protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G protein-linked receptors (GPLR), form a large group of evolutionarily related proteins that are cell surface receptors that detect molecules outside the cell and activate cellular responses.

See Protein kinase C and G protein-coupled receptor

Gastric acid

Gastric acid or stomach acid is the acidic component – hydrochloric acid of gastric juice, produced by parietal cells in the gastric glands of the stomach lining.

See Protein kinase C and Gastric acid

Gastrointestinal tract

The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans and other animals, including the esophagus, stomach, and intestines.

See Protein kinase C and Gastrointestinal tract

Gluconeogenesis

Gluconeogenesis (GNG) is a metabolic pathway that results in the biosynthesis of glucose from certain non-carbohydrate carbon substrates.

See Protein kinase C and Gluconeogenesis

Glutamate (neurotransmitter)

In neuroscience, glutamate is the anion of glutamic acid in its role as a neurotransmitter (a chemical that nerve cells use to send signals to other cells).

See Protein kinase C and Glutamate (neurotransmitter)

Glutamic acid

Glutamic acid (symbol Glu or E; the anionic form is known as glutamate) is an α-amino acid that is used by almost all living beings in the biosynthesis of proteins.

See Protein kinase C and Glutamic acid

Glycogenolysis

Glycogenolysis is the breakdown of glycogen (n) to glucose-1-phosphate and glycogen (n-1).

See Protein kinase C and Glycogenolysis

Gnathostomata

Gnathostomata (from Ancient Greek: γνάθος 'jaw' + στόμα 'mouth') are the jawed vertebrates.

See Protein kinase C and Gnathostomata

Gossypol

Gossypol is a natural phenol derived from the cotton plant (genus Gossypium).

See Protein kinase C and Gossypol

Gq alpha subunit

Gq protein alpha subunit is a family of heterotrimeric G protein alpha subunits.

See Protein kinase C and Gq alpha subunit

Hepatocyte

A hepatocyte is a cell of the main parenchymal tissue of the liver.

See Protein kinase C and Hepatocyte

Human digestive system

The human digestive system consists of the gastrointestinal tract plus the accessory organs of digestion (the tongue, salivary glands, pancreas, liver, and gallbladder).

See Protein kinase C and Human digestive system

Hydrophobe

In chemistry, hydrophobicity is the physical property of a molecule that is seemingly repelled from a mass of water (known as a hydrophobe).

See Protein kinase C and Hydrophobe

Hydroxy group

In chemistry, a hydroxy or hydroxyl group is a functional group with the chemical formula and composed of one oxygen atom covalently bonded to one hydrogen atom.

See Protein kinase C and Hydroxy group

Immune system

The immune system is a network of biological systems that protects an organism from diseases.

See Protein kinase C and Immune system

Immunodeficiency

Immunodeficiency, also known as immunocompromisation, is a state in which the immune system's ability to fight infectious diseases and cancer is compromised or entirely absent.

See Protein kinase C and Immunodeficiency

Ingenol mebutate

Ingenol mebutate, sold under the brand name Picato, is a substance that is found in the sap of the plant Euphorbia peplus, commonly known as petty spurge, and is an inducer of apoptosis.

See Protein kinase C and Ingenol mebutate

Innate immune system

The innate immune system or nonspecific immune system is one of the two main immunity strategies (the other being the adaptive immune system) in vertebrates.

See Protein kinase C and Innate immune system

Integumentary system

The integumentary system is the set of organs forming the outermost layer of an animal's body.

See Protein kinase C and Integumentary system

Intrinsically disordered proteins

In molecular biology, an intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered three-dimensional structure, typically in the absence of its macromolecular interaction partners, such as other proteins or RNA.

See Protein kinase C and Intrinsically disordered proteins

Ionomycin

Ionomycin is an ionophore and an antibiotic that binds calcium ions (Ca2+) in a ratio 1:1.

See Protein kinase C and Ionomycin

Ionotropic effect

An ionotropic effect is the effect of a transmitter substance or hormone that activates or deactivates ionotropic receptors (ligand-gated ion channels).

See Protein kinase C and Ionotropic effect

Iris dilator muscle

The iris dilator muscle (pupil dilator muscle, pupillary dilator, radial muscle of iris, radiating fibers), is a smooth muscle of the eye, running radially in the iris and therefore fit as a dilator.

See Protein kinase C and Iris dilator muscle

Iris sphincter muscle

The iris sphincter muscle (pupillary sphincter, pupillary constrictor, circular muscle of iris, circular fibers) is a muscle in the part of the eye called the iris.

See Protein kinase C and Iris sphincter muscle

Isozyme

In biochemistry, isozymes (also known as isoenzymes or more generally as multiple forms of enzymes) are enzymes that differ in amino acid sequence but catalyze the same chemical reaction.

See Protein kinase C and Isozyme

Kidney

In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation.

See Protein kinase C and Kidney

Killer-cell immunoglobulin-like receptor

Killer-cell immunoglobulin-like receptors (KIRs), are a family of type I transmembrane glycoproteins expressed on the plasma membrane of natural killer (NK) cells and a minority of T cells.

See Protein kinase C and Killer-cell immunoglobulin-like receptor

Lacrimal gland

The lacrimal glands are paired exocrine glands, one for each eye, found in most terrestrial vertebrates and some marine mammals, that secrete the aqueous layer of the tear film.

See Protein kinase C and Lacrimal gland

Ligand

In coordination chemistry, a ligand is an ion or molecule with a functional group that binds to a central metal atom to form a coordination complex.

See Protein kinase C and Ligand

Lymphocyte

A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates.

See Protein kinase C and Lymphocyte

MALT1

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 is a protein that in humans is encoded by the MALT1 gene.

See Protein kinase C and MALT1

MARCKS

Myristoylated alanine-rich C-kinase substrate is a protein that in humans is encoded by the MARCKS gene.

See Protein kinase C and MARCKS

Mincle receptor

Macrophage inducible Ca2+-dependent lectin receptor, (abbreviated to Mincle), is a member of the C-type lectin superfamily encoded by the gene CLEC4E.

See Protein kinase C and Mincle receptor

Mitogen-activated protein kinase

A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. Protein kinase C and mitogen-activated protein kinase are eC 2.7.11 and protein kinases.

See Protein kinase C and Mitogen-activated protein kinase

Miyabenol C

Miyabenol C is a stilbenoid.

See Protein kinase C and Miyabenol C

Most recent common ancestor

In biology and genetic genealogy, the most recent common ancestor (MRCA), also known as the last common ancestor (LCA), of a set of organisms is the most recent individual from which all the organisms of the set are descended.

See Protein kinase C and Most recent common ancestor

Muscarinic acetylcholine receptor M1

The muscarinic acetylcholine receptor M1, also known as the cholinergic receptor, muscarinic 1, is a muscarinic receptor that in humans is encoded by the CHRM1 gene.

See Protein kinase C and Muscarinic acetylcholine receptor M1

Muscarinic acetylcholine receptor M3

The muscarinic acetylcholine receptor, also known as cholinergic/acetylcholine receptor M3, or the muscarinic 3, is a muscarinic acetylcholine receptor encoded by the human gene CHRM3.

See Protein kinase C and Muscarinic acetylcholine receptor M3

Myelocyte

A myelocyte is a young cell of the granulocytic series, occurring normally in bone marrow (can be found in circulating blood when caused by certain diseases).

See Protein kinase C and Myelocyte

Myricitrin

Myricitrin is a plant compound, the 3-O-α-L-rhamnopyranoside of myricetin.

See Protein kinase C and Myricitrin

N-terminus

The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide, referring to the free amine group (-NH2) located at the end of a polypeptide.

See Protein kinase C and N-terminus

Nervous system

In biology, the nervous system is the highly complex part of an animal that coordinates its actions and sensory information by transmitting signals to and from different parts of its body.

See Protein kinase C and Nervous system

Neuron

A neuron, neurone, or nerve cell is an excitable cell that fires electric signals called action potentials across a neural network in the nervous system.

See Protein kinase C and Neuron

NF-κB

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription of DNA, cytokine production and cell survival.

See Protein kinase C and NF-κB

NMDA receptor

The N-methyl-D-aspartate receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca2+ ion channel found in neurons.

See Protein kinase C and NMDA receptor

Opisthokont

The opisthokonts are a broad group of eukaryotes, including both the animal and fungus kingdoms.

See Protein kinase C and Opisthokont

Parietal cell

Parietal cells (also known as oxyntic cells) are epithelial cells in the stomach that secrete hydrochloric acid (HCl) and intrinsic factor.

See Protein kinase C and Parietal cell

Phorbol esters

Phorbol esters are a class of chemical compounds found in a variety of plants, particularly in the families Euphorbiaceae and Thymelaeaceae.

See Protein kinase C and Phorbol esters

Phosphatidylserine

Phosphatidylserine (abbreviated Ptd-L-Ser or PS) is a phospholipid and is a component of the cell membrane.

See Protein kinase C and Phosphatidylserine

Phosphoinositide-dependent kinase-1

In the field of biochemistry, PDPK1 refers to the protein 3-phosphoinositide-dependent protein kinase-1, an enzyme which is encoded by the PDPK1 gene in humans. Protein kinase C and Phosphoinositide-dependent kinase-1 are eC 2.7.11 and protein kinases.

See Protein kinase C and Phosphoinositide-dependent kinase-1

Phospholipase

A phospholipase is an enzyme that hydrolyzes phospholipids into fatty acids and other lipophilic substances.

See Protein kinase C and Phospholipase

Phospholipase C

Phospholipase C (PLC) is a class of membrane-associated enzymes that cleave phospholipids just before the phosphate group (see figure).

See Protein kinase C and Phospholipase C

Phospholipid

Phospholipids are a class of lipids whose molecule has a hydrophilic "head" containing a phosphate group and two hydrophobic "tails" derived from fatty acids, joined by an alcohol residue (usually a glycerol molecule).

See Protein kinase C and Phospholipid

Phosphorylation

In biochemistry, phosphorylation is the attachment of a phosphate group to a molecule or an ion.

See Protein kinase C and Phosphorylation

PKC alpha

Protein kinase C alpha (PKCα) is an enzyme that in humans is encoded by the PRKCA gene. Protein kinase C and PKC alpha are eC 2.7.11 and protein kinases.

See Protein kinase C and PKC alpha

PKN2

Serine/threonine-protein kinase N2 is an enzyme that in humans and Strongylocentrotus purpuratus is encoded by the PKN2 gene. Protein kinase C and PKN2 are eC 2.7.11.

See Protein kinase C and PKN2

PKN3 (gene)

PKN3 is a protein kinase C-related molecule and thought to be an effector mediating malignant cell growth downstream of activated phosphoinositide 3-kinase (PI3K). Protein kinase C and PKN3 (gene) are eC 2.7.11.

See Protein kinase C and PKN3 (gene)

Platelet

Platelets or thrombocytes are a blood component whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.

See Protein kinase C and Platelet

Polyploidy

Polyploidy is a condition in which the cells of an organism have more than one pair of (homologous) chromosomes.

See Protein kinase C and Polyploidy

Potassium

Potassium is a chemical element; it has symbol K (from Neo-Latin kalium) and atomic number19.

See Protein kinase C and Potassium

PRKCB1

Protein kinase C beta type is an enzyme that in humans is encoded by the PRKCB gene. Protein kinase C and PRKCB1 are eC 2.7.11.

See Protein kinase C and PRKCB1

PRKCD

Protein kinase C delta type (or PKC-δ) is an enzyme that in humans is encoded by the PRKCD gene. Protein kinase C and PRKCD are eC 2.7.11.

See Protein kinase C and PRKCD

PRKCE

Protein kinase C epsilon type (PKCε) is an enzyme that in humans is encoded by the PRKCE gene. Protein kinase C and PRKCE are eC 2.7.11.

See Protein kinase C and PRKCE

PRKCG

Protein kinase C gamma type is an enzyme that in humans is encoded by the PRKCG gene. Protein kinase C and PRKCG are eC 2.7.11.

See Protein kinase C and PRKCG

PRKCH

Protein kinase C eta type is an enzyme that in humans is encoded by the PRKCH gene. Protein kinase C and PRKCH are eC 2.7.11.

See Protein kinase C and PRKCH

PRKCI

Protein kinase C iota type is an enzyme that in humans is encoded by the PRKCI gene. Protein kinase C and PRKCI are eC 2.7.11.

See Protein kinase C and PRKCI

PRKCQ

Protein kinase C theta (PKC-θ) is an enzyme that in humans is encoded by the PRKCQ gene. Protein kinase C and PRKCQ are eC 2.7.11.

See Protein kinase C and PRKCQ

PRKD2

Serine/threonine-protein kinase D2 or PKD2 is an enzyme that in humans is encoded by the PRKD2 gene. Protein kinase C and PRKD2 are eC 2.7.11.

See Protein kinase C and PRKD2

PRKD3

Serine/threonine-protein kinase D3 (PKD3) or PKC-nu is an enzyme that in humans is encoded by the PRKD3 gene. Protein kinase C and PRKD3 are eC 2.7.11.

See Protein kinase C and PRKD3

Prostaglandin F2alpha

Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.

See Protein kinase C and Prostaglandin F2alpha

Protein

Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues.

See Protein kinase C and Protein

Protein isoform

A protein isoform, or "protein variant", is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.

See Protein kinase C and Protein isoform

Protein kinase

A protein kinase is a kinase which selectively modifies other proteins by covalently adding phosphates to them (phosphorylation) as opposed to kinases which modify lipids, carbohydrates, or other molecules. Protein kinase C and protein kinase are protein kinases.

See Protein kinase C and Protein kinase

Protein kinase A

In cell biology, protein kinase A (PKA) is a family of serine-threonine kinase whose activity is dependent on cellular levels of cyclic AMP (cAMP). Protein kinase C and protein kinase A are eC 2.7.11 and protein kinases.

See Protein kinase C and Protein kinase A

Protein kinase B

Protein kinase B (PKB), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration. Protein kinase C and protein kinase B are eC 2.7.11 and protein kinases.

See Protein kinase C and Protein kinase B

Protein kinase C zeta type

Protein kinase C, zeta (PKCζ), also known as PRKCZ, is a protein in humans that is encoded by the PRKCZ gene. Protein kinase C and protein kinase C zeta type are eC 2.7.11.

See Protein kinase C and Protein kinase C zeta type

Protein kinase D1

Serine/threonine-protein kinase D1 is an enzyme that in humans is encoded by the PRKD1 gene. Protein kinase C and Protein kinase D1 are eC 2.7.11.

See Protein kinase C and Protein kinase D1

Protein kinase N1

Serine/threonine-protein kinase N1 is an enzyme that in humans is encoded by the PKN1 gene. Protein kinase C and Protein kinase N1 are eC 2.7.11.

See Protein kinase C and Protein kinase N1

Proximal tubule

The proximal tubule is the segment of the nephron in kidneys which begins from the renal pole of the Bowman's capsule to the beginning of loop of Henle.

See Protein kinase C and Proximal tubule

RAF kinase

RAF kinases are a family of three serine/threonine-specific protein kinases that are related to retroviral oncogenes. Protein kinase C and RAF kinase are eC 2.7.11.

See Protein kinase C and RAF kinase

Receptor for activated C kinase 1

Receptor for activated C kinase 1 (RACK1), also known as guanine nucleotide-binding protein subunit beta-2-like 1 (GNB2L1), is a 35 kDa protein that in humans is encoded by the RACK1 gene.

See Protein kinase C and Receptor for activated C kinase 1

Reproductive system

The reproductive system of an organism, also known as the genital system, is the biological system made up of all the anatomical organs involved in sexual reproduction.

See Protein kinase C and Reproductive system

Respiratory system

The respiratory system (also respiratory apparatus, ventilatory system) is a biological system consisting of specific organs and structures used for gas exchange in animals and plants.

See Protein kinase C and Respiratory system

Ro-318220

Ro-318220 is a protein kinase C (PKC) inhibitor of the bisindolylmaleimide class.

See Protein kinase C and Ro-318220

Ruboxistaurin

Ruboxistaurin (proposed brand name Arxxant) is an investigational drug for diabetic retinopathy being investigated by Eli Lilly and Company.

See Protein kinase C and Ruboxistaurin

Salivary gland

The salivary glands in many vertebrates including mammals are exocrine glands that produce saliva through a system of ducts.

See Protein kinase C and Salivary gland

Seminal tract

The seminal tract is a part of the male reproductive system and consists of seminiferous tubules (tubuli seminiferi recti, rete testis, efferent ducts), epididymides (appendix), Vas deferens (ampulla) and ejaculatory ducts.

See Protein kinase C and Seminal tract

Sensory nervous system

The sensory nervous system is a part of the nervous system responsible for processing sensory information.

See Protein kinase C and Sensory nervous system

Serine

Serine (symbol Ser or S) is an α-amino acid that is used in the biosynthesis of proteins.

See Protein kinase C and Serine

Serine/threonine-specific protein kinase

A serine/threonine protein kinase is a kinase enzyme, in particular a protein kinase, that phosphorylates the OH group of the amino-acid residues serine or threonine, which have similar side chains. Protein kinase C and Serine/threonine-specific protein kinase are eC 2.7.11 and protein kinases.

See Protein kinase C and Serine/threonine-specific protein kinase

Serotonin

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.

See Protein kinase C and Serotonin

Signal transduction

Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events.

See Protein kinase C and Signal transduction

Smooth muscle

Smooth (soft) muscle is one of the three major types of vertebrate muscle tissue, the other being skeletal and cardiac muscle.

See Protein kinase C and Smooth muscle

Sodium–hydrogen antiporter 3

Sodium–hydrogen antiporter 3 also known as sodium–hydrogen exchanger 3 (NHE3) or solute carrier family 9 member 3 (SLC9A3) is a protein that in humans is encoded by the SLC9A3 gene.

See Protein kinase C and Sodium–hydrogen antiporter 3

Sodium–potassium pump

The sodium–potassium pump (sodium–potassium adenosine triphosphatase, also known as -ATPase, pump, or sodium–potassium ATPase) is an enzyme (an electrogenic transmembrane ATPase) found in the membrane of all animal cells.

See Protein kinase C and Sodium–potassium pump

Sphincter

A sphincter is a circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning.

See Protein kinase C and Sphincter

Substrate presentation

Substrate presentation is a biological process that activates a protein.

See Protein kinase C and Substrate presentation

Sweat gland

Sweat glands, also known as sudoriferous or sudoriparous glands,, are small tubular structures of the skin that produce sweat.

See Protein kinase C and Sweat gland

T-cell receptor

The T-cell receptor (TCR) is a protein complex found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules.

See Protein kinase C and T-cell receptor

Tamoxifen

Tamoxifen, sold under the brand name Nolvadex among others, is a selective estrogen receptor modulator used to prevent breast cancer in women and men.

See Protein kinase C and Tamoxifen

Threonine

Threonine (symbol Thr or T) is an amino acid that is used in the biosynthesis of proteins.

See Protein kinase C and Threonine

Thromboxane

Thromboxane is a member of the family of lipids known as eicosanoids.

See Protein kinase C and Thromboxane

Turn (biochemistry)

A turn is an element of secondary structure in proteins where the polypeptide chain reverses its overall direction.

See Protein kinase C and Turn (biochemistry)

Ureter

The ureters are tubes composed of smooth muscle that transport urine from the kidneys to the urinary bladder.

See Protein kinase C and Ureter

Urethral sphincters

The urethral sphincters are two muscles used to control the exit of urine in the urinary bladder through the urethra.

See Protein kinase C and Urethral sphincters

Urinary system

The human urinary system, also known as the urinary tract or renal system, consists of the kidneys, ureters, bladder, and the urethra.

See Protein kinase C and Urinary system

Uterus

The uterus (from Latin uterus,: uteri) or womb is the organ in the reproductive system of most female mammals, including humans, that accommodates the embryonic and fetal development of one or more embryos until birth.

See Protein kinase C and Uterus

Vasoconstriction

Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles.

See Protein kinase C and Vasoconstriction

Ventricular system

In neuroanatomy, the ventricular system is a set of four interconnected cavities known as cerebral ventricles in the brain.

See Protein kinase C and Ventricular system

Verbascoside

Verbascoside is a polyphenol glycoside in which the phenylpropanoid caffeic acid and the phenylethanoid hydroxytyrosol form an ester and an ether bond respectively, to the rhamnose part of a disaccharide, namely β-(3′,4′-dihydroxyphenyl)ethyl-O-α-L-rhamnopyranosyl(1→3)-β-D-(4-O-caffeoyl)-glucopyranoside.

See Protein kinase C and Verbascoside

Vitamin D

Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and for many other biological effects.

See Protein kinase C and Vitamin D

Vitamin D receptor

The vitamin D receptor (VDR also known as the calcitriol receptor) is a member of the nuclear receptor family of transcription factors.

See Protein kinase C and Vitamin D receptor

Weightlessness

Weightlessness is the complete or near-complete absence of the sensation of weight, i.e., zero apparent weight.

See Protein kinase C and Weightlessness

Yasutomi Nishizuka

was a prominent Japanese biochemist and made important contributions to the understanding of molecular mechanism of signal transduction across the cell membrane.

See Protein kinase C and Yasutomi Nishizuka

12-O-Tetradecanoylphorbol-13-acetate

12-O-Tetradecanoylphorbol-13-acetate (TPA), also commonly known as tetradecanoylphorbol acetate, tetradecanoyl phorbol acetate, and phorbol 12-myristate 13-acetate (PMA) is a diester of phorbol.

See Protein kinase C and 12-O-Tetradecanoylphorbol-13-acetate

5-HT2A receptor

The 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR).

See Protein kinase C and 5-HT2A receptor

5-HT2B receptor

5-Hydroxytryptamine receptor 2B (5-HT2B) also known as serotonin receptor 2B is a protein that in humans is encoded by the HTR2B gene.

See Protein kinase C and 5-HT2B receptor

5-HT2C receptor

The 5-HT2C receptor is a subtype of the 5-HT2 receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

See Protein kinase C and 5-HT2C receptor

References

[1] https://en.wikipedia.org/wiki/Protein_kinase_C

Also known as ATP:protein phosphotransferase (diacylglycerol-dependent), C-kinase, EC 2.7.11.13, Function of PKC, Function of protein kinase C, Inhibitor of protein kinase C, PKC inhibitor, PKC-θ, Protein kc, Protein kinase C beta, Protein kinase C inhibitor.

, Ependyma, Epidermal growth factor receptor, Euphorbia peplus, Excitatory postsynaptic potential, Fungus, G protein-coupled receptor, Gastric acid, Gastrointestinal tract, Gluconeogenesis, Glutamate (neurotransmitter), Glutamic acid, Glycogenolysis, Gnathostomata, Gossypol, Gq alpha subunit, Hepatocyte, Human digestive system, Hydrophobe, Hydroxy group, Immune system, Immunodeficiency, Ingenol mebutate, Innate immune system, Integumentary system, Intrinsically disordered proteins, Ionomycin, Ionotropic effect, Iris dilator muscle, Iris sphincter muscle, Isozyme, Kidney, Killer-cell immunoglobulin-like receptor, Lacrimal gland, Ligand, Lymphocyte, MALT1, MARCKS, Mincle receptor, Mitogen-activated protein kinase, Miyabenol C, Most recent common ancestor, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M3, Myelocyte, Myricitrin, N-terminus, Nervous system, Neuron, NF-κB, NMDA receptor, Opisthokont, Parietal cell, Phorbol esters, Phosphatidylserine, Phosphoinositide-dependent kinase-1, Phospholipase, Phospholipase C, Phospholipid, Phosphorylation, PKC alpha, PKN2, PKN3 (gene), Platelet, Polyploidy, Potassium, PRKCB1, PRKCD, PRKCE, PRKCG, PRKCH, PRKCI, PRKCQ, PRKD2, PRKD3, Prostaglandin F2alpha, Protein, Protein isoform, Protein kinase, Protein kinase A, Protein kinase B, Protein kinase C zeta type, Protein kinase D1, Protein kinase N1, Proximal tubule, RAF kinase, Receptor for activated C kinase 1, Reproductive system, Respiratory system, Ro-318220, Ruboxistaurin, Salivary gland, Seminal tract, Sensory nervous system, Serine, Serine/threonine-specific protein kinase, Serotonin, Signal transduction, Smooth muscle, Sodium–hydrogen antiporter 3, Sodium–potassium pump, Sphincter, Substrate presentation, Sweat gland, T-cell receptor, Tamoxifen, Threonine, Thromboxane, Turn (biochemistry), Ureter, Urethral sphincters, Urinary system, Uterus, Vasoconstriction, Ventricular system, Verbascoside, Vitamin D, Vitamin D receptor, Weightlessness, Yasutomi Nishizuka, 12-O-Tetradecanoylphorbol-13-acetate, 5-HT2A receptor, 5-HT2B receptor, 5-HT2C receptor.