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Rectal administration, the Glossary

Rectal administration (colloquially known as boofing or plugging) uses the rectum as a route of administration for medication and other fluids, which are absorbed by the rectum's blood vessels,The rectum has numerous blood vessels available to absorb drugs: upwards 2/3rds of the dose bypasses first-pass metabolism through systemic distribution and the rest is taken through the liver and metabolized via the hepatic portal system.^[1]

Absorption (pharmacology)

Absorption is the journey of a drug travelling from the site of administration to the site of action.

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Asepsis

Asepsis is the state of being free from disease-causing micro-organisms (such as pathogenic bacteria, viruses, pathogenic fungi, and parasites).

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Bioavailability

In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation.

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Biological system

A biological system is a complex network which connects several biologically relevant entities.

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Blood vessel

Blood vessels are the structures of the circulatory system that transport blood throughout the human body.

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Blood–brain barrier

The blood–brain barrier (BBB) is a highly selective semipermeable border of endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood.

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Bowel obstruction

Bowel obstruction, also known as intestinal obstruction, is a mechanical or functional obstruction of the intestines which prevents the normal movement of the products of digestion.

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord.

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Circulatory system

The circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate.

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Drug

A drug is any chemical substance other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect.

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Dysphagia

Dysphagia is difficulty in swallowing.

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End-of-life care

End-of-life care (EOLC) is health care provided in the time leading up to a person's death.

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Enema

An enema, also known as a clyster, is an injection of fluid into the lower bowel by way of the rectum. Rectal administration and enema are rectum and routes of administration.

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First pass effect

The first pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism at a specific location in the body which leads to a reduction in the concentration of the active drug before it reaches the site of action or systemic circulation.

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Hepatic portal system

In human anatomy, the hepatic portal system or portal venous system is the system of veins comprising the portal vein and its tributaries.

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Hospice

Hospice care is a type of health care that focuses on the palliation of a terminally ill patient's pain and symptoms and attending to their emotional and spiritual needs at the end of life.

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Ileus

Ileus is a disruption of the normal propulsive ability of the intestine.

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Inferior rectal veins

The lower part of the external hemorrhoidal plexus is drained by the inferior rectal veins (or inferior hemorrhoidal veins) into the internal pudendal vein.

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Inhalation

Inhalation (or inspiration) happens when air or other gases enter the lungs.

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Insufflation (medicine)

Insufflation (lit) is the act of blowing something (such as a gas, powder, or vapor) into a body cavity. Rectal administration and Insufflation (medicine) are routes of administration.

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Intravenous therapy

Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.

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Large intestine

The large intestine, also known as the large bowel, is the last part of the gastrointestinal tract and of the digestive system in tetrapods.

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Liquid

A liquid is a nearly incompressible fluid that conforms to the shape of its container but retains a nearly constant volume independent of pressure.

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Long-term care

Long-term care (LTC) is a variety of services which help meet both the medical and non-medical needs of people with a chronic illness or disability who cannot care for themselves for long periods.

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Macy catheter

The Macy Catheter is a specialized catheter designed to provide comfortable and discreet administration of ongoing medications via the rectal route. Rectal administration and Macy catheter are routes of administration.

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Medication

A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

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Middle rectal veins

The middle rectal veins (or middle hemorrhoidal vein) take origin in the hemorrhoidal plexus and receive tributaries from the bladder, prostate, and seminal vesicle.

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Nausea

Nausea is a diffuse sensation of unease and discomfort, sometimes perceived as an urge to vomit.

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Oral administration

| name. Rectal administration and Oral administration are routes of administration.

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Organ (biology)

In a multicellular organism, an organ is a collection of tissues joined in a structural unit to serve a common function.

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Palliative care

Palliative care (derived from the Latin root, or 'to cloak') is an interdisciplinary medical caregiving approach aimed at optimizing quality of life and mitigating suffering among people with serious, complex, and often terminal illnesses.

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Patient

A patient is any recipient of health care services that are performed by healthcare professionals.

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Peripheral nervous system

The peripheral nervous system (PNS) is one of two components that make up the nervous system of bilateral animals, with the other part being the central nervous system (CNS).

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Rectal discharge

Rectal discharge is intermittent or continuous expression of liquid from the anus (per rectum). Rectal administration and Rectal discharge are rectum.

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Rectum

The rectum (rectums or recta) is the final straight portion of the large intestine in humans and some other mammals, and the gut in others.

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Route of administration

In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body. Rectal administration and route of administration are routes of administration.

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Smoking

Smoking is a practice in which a substance is combusted and the resulting smoke is typically inhaled to be tasted and absorbed into the bloodstream of a person.

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Solution (chemistry)

In chemistry, a solution is a special type of homogeneous mixture composed of two or more substances.

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Subcutaneous administration

Subcutaneous administration is the insertion of medications beneath the skin either by injection or infusion. Rectal administration and Subcutaneous administration are routes of administration.

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Superior rectal vein

The inferior mesenteric vein begins in the rectum as the superior rectal vein (superior hemorrhoidal vein), which has its origin in the hemorrhoidal plexus, and through this plexus communicates with the middle and inferior hemorrhoidal veins. Rectal administration and superior rectal vein are rectum.

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Suppository

A suppository is a dosage form used to deliver medications by insertion into a body orifice (any opening in the body), where it dissolves or melts to exert local or systemic effects. Rectal administration and suppository are rectum and routes of administration.

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Vaporization

Vaporization (or vaporisation) of an element or compound is a phase transition from the liquid phase to vapor.

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Vomiting

Vomiting (also known as emesis and throwing up) is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose.

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References

[1] https://en.wikipedia.org/wiki/Rectal_administration

Also known as Rectal (medical), Rectal (medicine).

Rectal administration, the Glossary

Table of Contents

See also

Rectum

References