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Rezvilutamide, the Glossary

Index Rezvilutamide

Rezvilutamide, sold under the brand name Ariane, is a nonsteroidal antiandrogen which is approved for the treatment of prostate cancer in China and is or was under development for the treatment of breast cancer.[1]

Table of Contents

  1. 14 relations: Androgen receptor, Apalutamide, Binding selectivity, Brain, Breast cancer, China, Distribution (pharmacology), Enzalutamide, Jiangsu Hengrui, Nonsteroidal antiandrogen, Prostate cancer, Proxalutamide, Receptor antagonist, Structural analog.

  2. Benzonitriles
  3. Drugs developed by Jiangsu Hengrui
  4. Imidazolidines
  5. Sulfur compounds

Androgen receptor

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone, in the cytoplasm and then translocating into the nucleus.

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Apalutamide

Apalutamide, sold under the brand name Erleada among others, is a nonsteroidal antiandrogen (NSAA) medication which is used in the treatment of prostate cancer. Rezvilutamide and Apalutamide are Hormonal antineoplastic drugs, Imidazolidines, nonsteroidal antiandrogens and Trifluoromethyl compounds.

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Binding selectivity

In chemistry, binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.

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Brain

The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.

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Breast cancer

Breast cancer is a cancer that develops from breast tissue.

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China

China, officially the People's Republic of China (PRC), is a country in East Asia.

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Distribution (pharmacology)

Distribution in pharmacology is a branch of pharmacokinetics which describes the reversible transfer of a drug from one location to another within the body.

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Enzalutamide

Enzalutamide, sold under the brand name Xtandi, is a nonsteroidal antiandrogen (NSAA) medication which is used in the treatment of prostate cancer. Rezvilutamide and Enzalutamide are Hormonal antineoplastic drugs, Imidazolidines, nonsteroidal antiandrogens and Trifluoromethyl compounds.

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Jiangsu Hengrui

Jiangsu Hengrui Pharmaceuticals Company Ltd., also known as Jiangsu Hengrui, is a Chinese pharmaceutical company that manufactures and distributes various types of drug packaging materials, cancer-treating antineoplastics, cardiovascular medication, painkillers, antibiotics, and related products.

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Nonsteroidal antiandrogen

A nonsteroidal antiandrogen (NSAA) is an antiandrogen with a nonsteroidal chemical structure. Rezvilutamide and nonsteroidal antiandrogen are Hormonal antineoplastic drugs and nonsteroidal antiandrogens.

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Prostate cancer

Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder.

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Proxalutamide

Proxalutamide (developmental code name GT-0918) is a nonsteroidal antiandrogen (NSAA) – specifically, a selective high-affinity silent antagonist of the androgen receptor (AR) – which is under development by Suzhou Kintor Pharmaceuticals, inc., a subsidiary of Kintor Pharmaceutical Limited, for the potential treatment of COVID-19, prostate cancer, and breast cancer. Rezvilutamide and Proxalutamide are Hormonal antineoplastic drugs, Imidazolidines, nonsteroidal antiandrogens and Trifluoromethyl compounds.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

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Structural analog

A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.

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See also

Benzonitriles

Drugs developed by Jiangsu Hengrui

Imidazolidines

Sulfur compounds

References

[1] https://en.wikipedia.org/wiki/Rezvilutamide

Also known as SHR-3680, SHR3680.