SMARCA4, the Glossary
Transcription activator BRG1 also known as ATP-dependent chromatin remodeler SMARCA4 is a protein that in humans is encoded by the SMARCA4 gene.[1]
Table of Contents
43 relations: ACTL6A, ARID1A, ARID1B, ATPase, BRCA1, Catenin beta-1, CBX5 (gene), CD44, Chromatin, Chromatin remodeling, CREB-binding protein, Cyclin E1, Darinaparsin, Endometrium, Estrogen receptor alpha, FANCA, Gene, Gene knockout, Glucocorticoid receptor, Helicase, HMOX1, HSP90B1, ING1, Medulloblastoma, Myc, P53, Patent ductus arteriosus, POLR2A, Prohibitin, Prophase, Protein, Protein–protein interaction, SIN3A, SMARCA2, SMARCB1, SMARCC1, SMARCC2, SMARCE1, Spermatogenesis, STAT2, STK11, SWI/SNF, Zona pellucida.
ACTL6A
Actin-like protein 6A is a protein that in humans is encoded by the ACTL6A gene.
ARID1A
AT-rich interactive domain-containing protein 1A is a protein that in humans is encoded by the ARID1A gene.
ARID1B
AT-rich interactive domain-containing protein 1B is a protein that in humans is encoded by the ARID1B gene.
ATPase
ATPases (Adenosine 5'-TriPhosphatase, adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion or the inverse reaction.
BRCA1
Breast cancer type 1 susceptibility protein is a protein that in humans is encoded by the BRCA1 gene.
Catenin beta-1
Catenin beta-1, also known as β-catenin (beta-catenin), is a protein that in humans is encoded by the CTNNB1 gene.
See SMARCA4 and Catenin beta-1
CBX5 (gene)
Chromobox protein homolog 5 is a protein that in humans is encoded by the CBX5 gene.
CD44
The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration.
See SMARCA4 and CD44
Chromatin
Chromatin is a complex of DNA and protein found in eukaryotic cells.
Chromatin remodeling
Chromatin remodeling is the dynamic modification of chromatin architecture to allow access of condensed genomic DNA to the regulatory transcription machinery proteins, and thereby control gene expression.
See SMARCA4 and Chromatin remodeling
CREB-binding protein
CREB-binding protein, also known as CREBBP or CBP or KAT3A, (where CREB is cAMP response element-binding protein) is a coactivator encoded by the CREBBP gene in humans, located on chromosome 16p13.3.
See SMARCA4 and CREB-binding protein
Cyclin E1
G1/S-specific cyclin-E1 is a protein that in humans is encoded by the CCNE1 gene. SMARCA4 and cyclin E1 are genes on human chromosome 19.
Darinaparsin
Darinaparsin (trade names Darvias and Zinapar) is a drug for the treatment of various types of cancer.
Endometrium
The endometrium is the inner epithelial layer, along with its mucous membrane, of the mammalian uterus.
Estrogen receptor alpha
Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a nuclear receptor (mainly found as a chromatin-binding protein) that is activated by the sex hormone estrogen.
See SMARCA4 and Estrogen receptor alpha
FANCA
Fanconi anaemia, complementation group A, also known as FAA, FACA and FANCA, is a protein which in humans is encoded by the FANCA gene.
Gene
In biology, the word gene has two meanings.
See SMARCA4 and Gene
Gene knockout
Gene knockouts (also known as gene deletion or gene inactivation) are a widely used genetic engineering technique that involves the targeted removal or inactivation of a specific gene within an organism's genome.
Glucocorticoid receptor
The glucocorticoid receptor (GR or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind.
See SMARCA4 and Glucocorticoid receptor
Helicase
Helicases are a class of enzymes thought to be vital to all organisms.
HMOX1
HMOX1 (heme oxygenase 1 gene) is a human gene that encodes for the enzyme heme oxygenase 1.
HSP90B1
Heat shock protein 90kDa beta member 1 (HSP90B1), known also as endoplasmin, gp96, grp94, or ERp99, is a chaperone protein that in humans is encoded by the HSP90B1 gene.
ING1
Inhibitor of growth protein 1 is a protein that in humans is encoded by the ING1 gene.
See SMARCA4 and ING1
Medulloblastoma
Medulloblastoma is a common type of primary brain cancer in children.
See SMARCA4 and Medulloblastoma
Myc
Myc is a family of regulator genes and proto-oncogenes that code for transcription factors.
See SMARCA4 and Myc
P53
p53, also known as Tumor protein P53, cellular tumor antigen p53 (UniProt name), or transformation-related protein 53 (TRP53) is a regulatory protein that is often mutated in human cancers.
See SMARCA4 and P53
Patent ductus arteriosus
Patent ductus arteriosus (PDA) is a medical condition in which the ductus arteriosus fails to close after birth: this allows a portion of oxygenated blood from the left heart to flow back to the lungs through the aorta, which has a higher blood pressure, to the pulmonary artery, which has a lower blood pressure.
See SMARCA4 and Patent ductus arteriosus
POLR2A
DNA-directed RNA polymerase II subunit RPB1, also known as RPB1, is an enzyme that is encoded by the POLR2A gene in humans.
Prohibitin
Prohibitin, also known as PHB, is a protein that in humans is encoded by the PHB gene.
Prophase
Prophase is the first stage of cell division in both mitosis and meiosis.
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues.
Protein–protein interaction
Protein–protein interactions (PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by interactions that include electrostatic forces, hydrogen bonding and the hydrophobic effect.
See SMARCA4 and Protein–protein interaction
SIN3A
Paired amphipathic helix protein Sin3a is a protein that in humans is encoded by the SIN3A gene.
SMARCA2
Probable global transcription activator SNF2L2 is a protein that in humans is encoded by the SMARCA2 gene.
SMARCB1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 is a protein that in humans is encoded by the SMARCB1 gene.
SMARCC1
SWI/SNF complex subunit SMARCC1 is a protein that in humans is encoded by the SMARCC1 gene.
SMARCC2
SWI/SNF complex subunit SMARCC2 is a protein that in humans is encoded by the SMARCC2 gene.
SMARCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 is a protein that in humans is encoded by the SMARCE1 gene.
Spermatogenesis
Spermatogenesis is the process by which haploid spermatozoa develop from germ cells in the seminiferous tubules of the testicle.
See SMARCA4 and Spermatogenesis
STAT2
Signal transducer and activator of transcription 2 is a protein that in humans is encoded by the STAT2 gene.
STK11
Serine/threonine kinase 11 (STK11) also known as liver kinase B1 (LKB1) or renal carcinoma antigen NY-REN-19 is a protein kinase that in humans is encoded by the STK11 gene. SMARCA4 and STK11 are genes on human chromosome 19.
SWI/SNF
In molecular biology, SWI/SNF (SWItch/Sucrose Non-Fermentable), is a subfamily of ATP-dependent chromatin remodeling complexes, which is found in eukaryotes.
Zona pellucida
The zona pellucida (Latin meaning "transparent zone") is the specialized area surrounding mammalian oocytes (eggs).
See SMARCA4 and Zona pellucida
References
[1] https://en.wikipedia.org/wiki/SMARCA4
Also known as BAF190, BRG1, SMARCA4 (gene), SNF2L4, SWI2.