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Schnitzler syndrome, the Glossary

Schnitzler syndrome or Schnitzler's syndrome is a rare disease characterised by onset around middle age of chronic hives (urticaria) and periodic fever, bone pain and joint pain (sometimes with joint inflammation), weight loss, malaise, fatigue, swollen lymph glands and enlarged spleen and liver.^[1]

56 relations: AA amyloidosis, Adult-onset Still's disease, Anakinra, Anemia of chronic disease, Angioedema, Arthralgia, Arthritis, Autoimmunity, Bence Jones protein, Biopsy, Blood test, Bone pain, C-reactive protein, Canakinumab, Chronic condition, Corticosteroid, Cryoglobulinemia, Delphi method, Differential diagnosis, Erythrocyte sedimentation rate, Fatigue, Fever, Gamma globulin, Hepatosplenomegaly, Hives, Immunoglobulin G, Immunoglobulin light chain, Immunoglobulin M, Immunosuppressive drug, Interferon type I, Interleukin-1 family, Leukocytosis, Liliane Schnitzler, List of eponymous diseases, List of skin conditions, Lymphadenopathy, Lymphoma, Lymphoproliferative disorders, Malaise, Mastocytosis, Monoclonal gammopathy of undetermined significance, Muckle–Wells syndrome, Myeloma protein, Neonatal-onset multisystem inflammatory disease, Neutrophil, NHS England, Nonsteroidal anti-inflammatory drug, Osteosclerosis, Periodic fever syndrome, Radiology, ... Expand index (6 more) »
Autoinflammatory syndromes
Urticaria and angioedema

AA amyloidosis

AA amyloidosis is a form of amyloidosis, a disease characterized by the abnormal deposition of fibers of insoluble protein in the extracellular space of various tissues and organs. Schnitzler syndrome and aA amyloidosis are rare diseases.

See Schnitzler syndrome and AA amyloidosis

Adult-onset Still's disease

Adult-onset Still's disease (AOSD) is a form of Still's disease, a rare systemic autoinflammatory disease characterized by the classic triad of fevers, joint pain, and a distinctive salmon-colored bumpy rash. Schnitzler syndrome and Adult-onset Still's disease are rare diseases.

See Schnitzler syndrome and Adult-onset Still's disease

Anakinra

Anakinra, sold under the brand name Kineret, is a biopharmaceutical medication used to treat rheumatoid arthritis, cryopyrin-associated periodic syndromes, familial Mediterranean fever, and Still's disease.

See Schnitzler syndrome and Anakinra

Anemia of chronic disease

Anemia of chronic disease (ACD) or anemia of chronic inflammation is a form of anemia seen in chronic infection, chronic immune activation, and malignancy.

See Schnitzler syndrome and Anemia of chronic disease

Angioedema

Angioedema is an area of swelling (edema) of the lower layer of skin and tissue just under the skin or mucous membranes. Schnitzler syndrome and Angioedema are urticaria and angioedema.

See Schnitzler syndrome and Angioedema

Arthralgia

Arthralgia literally means 'joint pain'.

See Schnitzler syndrome and Arthralgia

Arthritis

Arthritis is a term often used to mean any disorder that affects joints.

See Schnitzler syndrome and Arthritis

Autoimmunity

In immunology, autoimmunity is the system of immune responses of an organism against its own healthy cells, tissues and other normal body constituents.

See Schnitzler syndrome and Autoimmunity

Bence Jones protein

Bence Jones protein is a monoclonal globulin protein or immunoglobulin light chain found in the urine, with a molecular weight of 22–24 kDa.

See Schnitzler syndrome and Bence Jones protein

Biopsy

A biopsy is a medical test commonly performed by a surgeon, an interventional radiologist, or an interventional cardiologist.

See Schnitzler syndrome and Biopsy

Blood test

A blood test is a laboratory analysis performed on a blood sample that is usually extracted from a vein in the arm using a hypodermic needle, or via fingerprick.

See Schnitzler syndrome and Blood test

Bone pain

Bone pain (also known medically by several other names) is pain coming from a bone, and is caused by damaging stimuli.

See Schnitzler syndrome and Bone pain

C-reactive protein

C-reactive protein (CRP) is an annular (ring-shaped) pentameric protein found in blood plasma, whose circulating concentrations rise in response to inflammation.

See Schnitzler syndrome and C-reactive protein

Canakinumab

Canakinumab, sold under the brand name Ilaris, is a medication for the treatment of systemic juvenile idiopathic arthritis, active Still's disease, including adult-onset Still's disease, gout flares.

See Schnitzler syndrome and Canakinumab

Chronic condition

A chronic condition (also known as chronic disease or chronic illness) is a health condition or disease that is persistent or otherwise long-lasting in its effects or a disease that comes with time.

See Schnitzler syndrome and Chronic condition

Corticosteroid

Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.

See Schnitzler syndrome and Corticosteroid

Cryoglobulinemia

Cryoglobulinemia is a medical condition in which the blood contains large amounts of pathological cold sensitive antibodies called cryoglobulins – proteins (mostly immunoglobulins themselves) that become insoluble at reduced temperatures.

See Schnitzler syndrome and Cryoglobulinemia

Delphi method

The Delphi method or Delphi technique (also known as Estimate-Talk-Estimate or ETE) is a structured communication technique or method, originally developed as a systematic, interactive forecasting method that relies on a panel of experts.

See Schnitzler syndrome and Delphi method

Differential diagnosis

In healthcare, a differential diagnosis (DDx) is a method of analysis that distinguishes a particular disease or condition from others that present with similar clinical features.

See Schnitzler syndrome and Differential diagnosis

Erythrocyte sedimentation rate

The erythrocyte sedimentation rate (ESR or sed rate) is the rate at which red blood cells in anticoagulated whole blood descend in a standardized tube over a period of one hour.

See Schnitzler syndrome and Erythrocyte sedimentation rate

Fatigue

Fatigue describes a state of tiredness (which is not sleepiness), exhaustion or loss of energy.

See Schnitzler syndrome and Fatigue

Fever

Fever or pyrexia in humans is a body temperature above the normal range due to an increase in the body's temperature set point in the hypothalamus.

See Schnitzler syndrome and Fever

Gamma globulin

Gamma globulins are a class of globulins, identified by their position after serum protein electrophoresis.

See Schnitzler syndrome and Gamma globulin

Hepatosplenomegaly

Hepatosplenomegaly (commonly abbreviated HSM) is the simultaneous enlargement of both the liver (hepatomegaly) and the spleen (splenomegaly).

See Schnitzler syndrome and Hepatosplenomegaly

Hives

Hives, also known as urticaria, is a kind of skin rash with red, raised, itchy bumps. Schnitzler syndrome and Hives are urticaria and angioedema.

See Schnitzler syndrome and Hives

Immunoglobulin G

Immunoglobulin G (IgG) is a type of antibody.

See Schnitzler syndrome and Immunoglobulin G

Immunoglobulin light chain

The immunoglobulin light chain is the small polypeptide subunit of an antibody (immunoglobulin).

See Schnitzler syndrome and Immunoglobulin light chain

Immunoglobulin M

Immunoglobulin M (IgM) is the largest of several isotypes of antibodies (also known as immunoglobulin) that are produced by vertebrates.

See Schnitzler syndrome and Immunoglobulin M

Immunosuppressive drug

Immunosuppressive drugs, also known as immunosuppressive agents, immunosuppressants and antirejection medications, are drugs that inhibit or prevent the activity of the immune system.

See Schnitzler syndrome and Immunosuppressive drug

Interferon type I

The type-I interferons (IFN) are cytokines which play essential roles in inflammation, immunoregulation, tumor cells recognition, and T-cell responses.

See Schnitzler syndrome and Interferon type I

Interleukin-1 family

The Interleukin-1 family (IL-1 family) is a group of 11 cytokines that plays a central role in the regulation of immune and inflammatory responses to infections or sterile insults.

See Schnitzler syndrome and Interleukin-1 family

Leukocytosis

Leukocytosis is a condition in which the white cell (leukocyte) count is above the normal range in the blood.

See Schnitzler syndrome and Leukocytosis

Liliane Schnitzler

Liliane Schnitzler is a French dermatologist who described the eponymous Schnitzler's syndrome in 1972.

See Schnitzler syndrome and Liliane Schnitzler

List of eponymous diseases

An eponymous disease is a disease, disorder, condition, or syndrome named after a person, usually the physician or other health care professional who first identified the disease; less commonly, a patient who had the disease; rarely, a fictional character who exhibited signs of the disease or an actor or subject of a literary allusion, as characteristics associated with them were suggestive of symptoms observed in the disorder.

See Schnitzler syndrome and List of eponymous diseases

List of skin conditions

Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands.

See Schnitzler syndrome and List of skin conditions

Lymphadenopathy

Lymphadenopathy or adenopathy is a disease of the lymph nodes, in which they are abnormal in size or consistency.

See Schnitzler syndrome and Lymphadenopathy

Lymphoma

Lymphoma is a group of blood and lymph tumors that develop from lymphocytes (a type of white blood cell).

See Schnitzler syndrome and Lymphoma

Lymphoproliferative disorders

Lymphoproliferative disorders (LPDs) refer to a specific class of diagnoses, comprising a group of several conditions, in which lymphocytes are produced in excessive quantities.

See Schnitzler syndrome and Lymphoproliferative disorders

Malaise

In medicine, malaise is a feeling of general discomfort, uneasiness or lack of wellbeing and often the first sign of an infection or other disease.

See Schnitzler syndrome and Malaise

Mastocytosis

Mastocytosis, a type of mast cell disease, is a rare disorder affecting both children and adults caused by the accumulation of functionally defective mast cells (also called mastocytes) and CD34+ mast cell precursors. Schnitzler syndrome and Mastocytosis are rare diseases.

See Schnitzler syndrome and Mastocytosis

Monoclonal gammopathy of undetermined significance

Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia in which plasma cells or other types of antibody-producing cells secrete a myeloma protein, i.e. an abnormal antibody, into the blood; this abnormal protein is usually found during standard laboratory blood or urine tests.

See Schnitzler syndrome and Monoclonal gammopathy of undetermined significance

Muckle–Wells syndrome

Muckle–Wells syndrome (MWS) is a rare autosomal dominant disease which causes sensorineural deafness and recurrent hives, and can lead to amyloidosis. Schnitzler syndrome and Muckle–Wells syndrome are autoinflammatory syndromes.

See Schnitzler syndrome and Muckle–Wells syndrome

Myeloma protein

A myeloma protein is an abnormal antibody (immunoglobulin) or (more often) a fragment thereof, such as an immunoglobulin light chain, that is produced in excess by an abnormal monoclonal proliferation of plasma cells, typically in multiple myeloma or Monoclonal gammopathy of undetermined significance.

See Schnitzler syndrome and Myeloma protein

Neonatal-onset multisystem inflammatory disease

Neonatal-onset multisystem inflammatory disease is a rare genetic periodic fever syndrome which causes uncontrolled inflammation in multiple parts of the body starting in the newborn period. Schnitzler syndrome and Neonatal-onset multisystem inflammatory disease are rare diseases.

See Schnitzler syndrome and Neonatal-onset multisystem inflammatory disease

Neutrophil

Neutrophils (also known as neutrocytes, heterophils or polymorphonuclear leukocytes) are a type of white blood cell.

See Schnitzler syndrome and Neutrophil

NHS England

NHS England, formerly the NHS Commissioning Board, is an executive non-departmental public body of the Department of Health and Social Care.

See Schnitzler syndrome and NHS England

Nonsteroidal anti-inflammatory drug

Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots.

See Schnitzler syndrome and Nonsteroidal anti-inflammatory drug

Osteosclerosis

Osteosclerosis is a disorder characterized by abnormal hardening of bone and an elevation in bone density.

See Schnitzler syndrome and Osteosclerosis

Periodic fever syndrome

Periodic fever syndromes are a set of disorders characterized by recurrent episodes of systemic and organ-specific inflammation. Schnitzler syndrome and Periodic fever syndrome are autoinflammatory syndromes.

See Schnitzler syndrome and Periodic fever syndrome

Radiology

Radiology is the medical specialty that uses medical imaging to diagnose diseases and guide their treatment, within the bodies of humans and other animals.

See Schnitzler syndrome and Radiology

Rare disease

A rare disease is a disease that affects a small percentage of the population. Schnitzler syndrome and rare disease are rare diseases.

See Schnitzler syndrome and Rare disease

Skin biopsy

Skin biopsy is a biopsy technique in which a skin lesion is removed to be sent to a pathologist to render a microscopic diagnosis.

See Schnitzler syndrome and Skin biopsy

Syndrome

A syndrome is a set of medical signs and symptoms which are correlated with each other and often associated with a particular disease or disorder.

See Schnitzler syndrome and Syndrome

Waldenström macroglobulinemia

Waldenström macroglobulinemia is a type of cancer affecting two types of B cells: lymphoplasmacytoid cells and plasma cells.

See Schnitzler syndrome and Waldenström macroglobulinemia

Weight loss

Weight loss, in the context of medicine, health, or physical fitness, refers to a reduction of the total body mass, by a mean loss of fluid, body fat (adipose tissue), or lean mass (namely bone mineral deposits, muscle, tendon, and other connective tissue).

See Schnitzler syndrome and Weight loss

White blood cell

White blood cells (scientific name leukocytes), also called immune cells or immunocytes, are cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

See Schnitzler syndrome and White blood cell

References

[1] https://en.wikipedia.org/wiki/Schnitzler_syndrome

Also known as Late onset gammopathy with recurrent urticaria and fever, Schnitzler's syndrome, Schnitzlers syndrome.

, Rare disease, Skin biopsy, Syndrome, Waldenström macroglobulinemia, Weight loss, White blood cell.

Schnitzler syndrome, the Glossary

Table of Contents

See also

Autoinflammatory syndromes

Urticaria and angioedema

References