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Tolbutamide, the Glossary

Tolbutamide is a first-generation potassium channel blocker, sulfonylurea oral hypoglycemic medication.^[1]

32 relations: Blackout (drug-related amnesia), Chlorpropamide, Cimetidine, Coma, Convulsion, CYP2C19, Diabetes medication, Eli Lilly and Company, Food and Drug Administration, German military administration in occupied France during World War II, Glibenclamide, Glucose test, History of Germany (1945–1990), Hoechst AG, Insulin, Joslin Diabetes Center, Kidney, Liver, Metformin, Pancreas, Pharmacia, Potassium channel blocker, Salicylic acid, Sensitivity and specificity, Sulfonamide (medicine), Sulfonylurea, The New York Times, The Washington Post, Type 2 diabetes, University of Montpellier, Upjohn, Urine test strip.
Benzenesulfonylureas
Disulfiram-like drugs
P-Tosyl compounds

A drug-related blackout is a phenomenon caused by the intake of any substance or medication in which short-term and long-term memory creation is impaired, therefore causing a complete inability to recall the past.

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Chlorpropamide

Chlorpropamide is an antidiabetic drug, belonging to the sulfonylurea class of organic compounds. Tolbutamide and Chlorpropamide are Benzenesulfonylureas and potassium channel blockers.

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Cimetidine

Cimetidine, sold under the brand name Tagamet among others, is a histamine H2 receptor antagonist that inhibits stomach acid production.

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Coma

A coma is a deep state of prolonged unconsciousness in which a person cannot be awakened, fails to respond normally to painful stimuli, light, or sound, lacks a normal wake-sleep cycle and does not initiate voluntary actions.

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Convulsion

A convulsion is a medical condition where the body muscles contract and relax rapidly and repeatedly, resulting in uncontrolled shaking.

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CYP2C19

Cytochrome P450 2C19 (abbreviated CYP2C19) is an enzyme protein.

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Diabetes medication

Drugs used in diabetes treat diabetes mellitus by decreasing glucose levels in the blood.

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Eli Lilly and Company

Eli Lilly and Company is an American pharmaceutical company headquartered in Indianapolis, Indiana, with offices in 18 countries.

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Food and Drug Administration

The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services.

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German military administration in occupied France during World War II

The Military Administration in France (Militärverwaltung in Frankreich; Administration militaire en France) was an interim occupation authority established by Nazi Germany during World War II to administer the occupied zone in areas of northern and western France.

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Glibenclamide

Glibenclamide, also known as glyburide, is an antidiabetic medication used to treat type 2 diabetes. Tolbutamide and Glibenclamide are Disulfiram-like drugs and potassium channel blockers.

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Glucose test

Many types of glucose tests exist and they can be used to estimate blood sugar levels at a given time or, over a longer period of time, to obtain average levels or to see how fast body is able to normalize changed glucose levels.

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History of Germany (1945–1990)

The history of Germany from 1945 to 1990 comprises the period following World War II.

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Hoechst AG

Hoechst AG was a German chemicals, later life sciences, company that became Aventis Deutschland after its merger with France's Rhône-Poulenc S.A. in 1999.

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Insulin

Insulin (from Latin insula, 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (INS) gene.

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Joslin Diabetes Center

Joslin Diabetes Center is the world's largest diabetes research center, diabetes clinic, and provider of diabetes education.

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Kidney

In humans, the kidneys are two reddish-brown bean-shaped blood-filtering organs that are a multilobar, multipapillary form of mammalian kidneys, usually without signs of external lobulation.

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Liver

The liver is a major metabolic organ exclusively found in vertebrate animals, which performs many essential biological functions such as detoxification of the organism, and the synthesis of proteins and various other biochemicals necessary for digestion and growth.

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Metformin

Metformin, sold under the brand name Glucophage, among others, is the main first-line medication for the treatment of typenbsp2 diabetes, particularly in people who are overweight.

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Pancreas

The pancreas is an organ of the digestive system and endocrine system of vertebrates.

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Pharmacia

Pharmacia was a pharmaceutical and biotechnological company in Sweden that merged with the American pharmaceutical company Upjohn in 1995.

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Potassium channel blocker

Potassium channel blockers are agents which interfere with conduction through potassium channels. Tolbutamide and potassium channel blocker are potassium channel blockers.

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Salicylic acid

Salicylic acid is an organic compound with the formula HOC6H4COOH.

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Sensitivity and specificity

In medicine and statistics, sensitivity and specificity mathematically describe the accuracy of a test that reports the presence or absence of a medical condition.

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Sulfonamide (medicine)

Sulfonamide is a functional group (a part of a molecule) that is the basis of several groups of drugs, which are called sulphonamides, sulfa drugs or sulpha drugs. Tolbutamide and Sulfonamide (medicine) are Disulfiram-like drugs.

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Sulfonylurea

Sulfonylureas or sulphonylureas are a class of organic compounds used in medicine and agriculture. Tolbutamide and Sulfonylurea are Disulfiram-like drugs.

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The New York Times

The New York Times (NYT) is an American daily newspaper based in New York City.

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The Washington Post

The Washington Post, locally known as "the Post" and, informally, WaPo or WP, is an American daily newspaper published in Washington, D.C., the national capital.

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Type 2 diabetes

Type 2 diabetes (T2D), formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.

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University of Montpellier

The University of Montpellier (Université de Montpellier) is a public research university located in Montpellier, in south-east of France.

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Upjohn

The Upjohn Company was an American pharmaceutical manufacturing firm founded in 1886 in Hastings, Michigan, by Dr.

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Urine test strip

A urine test strip or dipstick is a basic diagnostic tool used to determine pathological changes in a patient's urine in standard urinalysis.

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References

[1] https://en.wikipedia.org/wiki/Tolbutamide

Also known as ATC code A10BB03, ATC code V04CA01, ATCvet code QA10BB03, ATCvet code QV04CA01, Aglicid, Apo-Tolbutamide, Arkozal, Artosin, Artozin, Butamid, Butamide, C12H18N2O3S, Diaben, Diabetamid, Diabetol, Diabuton, Diasulfon, Dirastan, Dolipol, Glyconon, Ipoglicone, Mobenol, Novo-Butamide, Orabet, Orezan, Orinase, Orinase Diagnostic, Orinaz, Oterben, Pramidex, Rastinon, Restinon, Sk-tolbutamide, Tol-Tab, Tolbusal, Tolbutamid, Tolbutamide sodium, Toluina, Tolumid, Toluvan, Tolylsulfonylbutylurea, Willbutamide.