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Trimethobenzamide, the Glossary

Trimethobenzamide (trade names Tebamide, Tigan) is an antiemetic used to prevent nausea and vomiting.^[1]

17 relations: Antiemetic, Chemoreceptor trigger zone, Domperidone, Dopamine receptor D2, Food and Drug Administration, GSK plc, Intramuscular injection, Jaundice, King Pharmaceuticals, Medscape, Medulla oblongata, Metoclopramide, Nausea, Parkinsonism, Receptor antagonist, Suppository, Vomiting.
D2 antagonists

Antiemetic

An antiemetic is a drug that is effective against vomiting and nausea. Trimethobenzamide and antiemetic are antiemetics.

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The chemoreceptor trigger zone (CTZ) is an area of the medulla oblongata that receives inputs from blood-borne drugs or hormones, and communicates with other structures in the vomiting center to initiate vomiting.

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Domperidone

Domperidone, sold under the brand name Motilium among others, is a dopamine antagonist medication which is used to treat nausea and vomiting and certain gastrointestinal problems like gastroparesis (delayed gastric emptying). Trimethobenzamide and Domperidone are antiemetics.

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Dopamine receptor D2

Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene.

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Food and Drug Administration

The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services.

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GSK plc

GSK plc (an acronym from its former name GlaxoSmithKline plc) is a British multinational pharmaceutical and biotechnology company with global headquarters in London.

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Intramuscular injection

Intramuscular injection, often abbreviated IM, is the injection of a substance into a muscle.

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Jaundice

Jaundice, also known as icterus, is a yellowish or greenish pigmentation of the skin and sclera due to high bilirubin levels.

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King Pharmaceuticals

King Pharmaceuticals, Inc. is a pharmaceutical company, a wholly owned subsidiary of Pfizer based in Bristol, Tennessee.

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Medscape

Medscape is a website providing access to medical information for clinicians and medical scientists; the organization also provides continuing education for physicians and other health professionals.

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Medulla oblongata

The medulla oblongata or simply medulla is a long stem-like structure which makes up the lower part of the brainstem.

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Metoclopramide

Metoclopramide is a medication used for stomach and esophageal problems. Trimethobenzamide and Metoclopramide are antiemetics and d2 antagonists.

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Nausea

Nausea is a diffuse sensation of unease and discomfort, sometimes perceived as an urge to vomit.

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Parkinsonism

Parkinsonism is a clinical syndrome characterized by tremor, bradykinesia (slowed movements), rigidity, and postural instability.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

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Suppository

A suppository is a dosage form used to deliver medications by insertion into a body orifice (any opening in the body), where it dissolves or melts to exert local or systemic effects.

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Vomiting

Vomiting (also known as emesis and throwing up) is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose.

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References

[1] https://en.wikipedia.org/wiki/Trimethobenzamide

Also known as Ametik hydrochloride, Benzacot, Nauseton, Stemetic, Tebamide, Tigan, Tribenzagan, Trimazide, Trimethobenzamide Hydrochloride.