Maleylpyruvate isomerase - Wikipedia
From Wikipedia, the free encyclopedia
| maleylpyruvate isomerase | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| EC no. | 5.2.1.4 | ||||||
| CAS no. | 9023-77-2 | ||||||
| Databases | |||||||
| IntEnz | IntEnz view | ||||||
| BRENDA | BRENDA entry | ||||||
| ExPASy | NiceZyme view | ||||||
| KEGG | KEGG entry | ||||||
| MetaCyc | metabolic pathway | ||||||
| PRIAM | profile | ||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||
| Gene Ontology | AmiGO / QuickGO | ||||||
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In enzymology, a maleylpyruvate isomerase (EC 5.2.1.4) is an enzyme that catalyzes the chemical reaction
- 3-maleylpyruvate
3-fumarylpyruvate
Hence, this enzyme has one substrate, 3-maleylpyruvate, and one product, 3-fumarylpyruvate.
This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is 3-maleylpyruvate cis-trans-isomerase. This enzyme participates in tyrosine metabolism.
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2NSF and 2NSG.
- Lack L (November 1961). "Enzymic cis-trans isomerization of maleylpyruvic acid". The Journal of Biological Chemistry. 236 (11): 2835–40. doi:10.1016/S0021-9258(19)76386-8. PMID 14461395.