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ENZYME - 1.14.14.115 11-oxo-beta-amyrin 30-oxidase

Accepted Name
11-oxo-beta-amyrin 30-oxidase
Alternative Name(s)
11-oxo-beta-amyrin 30-monooxygenase
CYP72A
CYP72A154
Reaction catalysed
11-oxo-beta-amyrin + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = glycyrrhetinate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)
Comment(s)
  • A cytochrome P450 (heme-thiolate) protein.
  • The enzyme from the plant Glycyrrhiza uralensis (licorice) is involved in the biosynthesis of the triterpenoid saponin glycyrrhizin.
  • The enzyme from the plant Medicago truncatula can also hydroxylate beta-amyrin.
  • Formerly EC 1.14.13.173.
Cross-references
BRENDA1.14.14.115
EC2PDB1.14.14.115
ExplorEnz1.14.14.115
PRIAM enzyme-specific profiles1.14.14.115
KEGG Ligand Database for Enzyme Nomenclature1.14.14.115
IUBMB Enzyme Nomenclature1.14.14.115
IntEnz1.14.14.115
MEDLINEFind literature relating to 1.14.14.115
MetaCyc1.14.14.115
Rhea expert-curated reactions1.14.14.115
UniProtKB/Swiss-Prot
H1A988, C7254_GLYURH1A981, C7263_MEDTR

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-