enzyme.expasy.org

ENZYME - 1.14.14.30 isobutylamine N-monooxygenase

Accepted Name
isobutylamine N-monooxygenase
Reaction catalysed
  • 2-methylpropan-1-amine + FADH2 + O2 = N-(2-methylpropyl)hydroxylamine + FAD + H2O + 2 H(+)
  • 2-methylpropan-1-amine + FMNH2 + O2 = N-(2-methylpropyl)hydroxylamine + FMN + H2O + 2 H(+)
Comment(s)
  • The enzyme, characterized from the bacterium Streptomyces viridifaciens, is part of a two component system that also includes a flavin reductase, which provides reduced flavin mononucleotide for this enzyme.
  • The enzyme, which is involved in the biosynthesis of the azoxy antibiotic valanimycin, has a similar activity with either FMNH2 or FADH2.
  • It exhibits broad specificity, and also accepts propan-1-amine, butan-1-amine, butan-2-amine and benzylamine.
Cross-references
BRENDA1.14.14.30
EC2PDB1.14.14.30
ExplorEnz1.14.14.30
KEGG Ligand Database for Enzyme Nomenclature1.14.14.30
IUBMB Enzyme Nomenclature1.14.14.30
MEDLINEFind literature relating to 1.14.14.30
MetaCyc1.14.14.30
Rhea expert-curated reactions1.14.14.30
UniProtKB/Swiss-Prot

P96072, VLMH_STRVF

View entry in original ENZYME format
View entry in raw text format (no links)

All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-