ENZYME - 1.14.99.53 lytic chitin monooxygenase

Accepted Name
lytic chitin monooxygenase
Alternative Name(s)
chitin oxidohydrolase
LPMO
Reaction catalysed
[(1->4)-N-acetyl-beta-D-glucosaminyl]n+m + reduced acceptor + O2 = [(1->4)-N-acetyl-beta-D-glucosaminyl]m-1-(1->4)-2-(acetylamino)-2-deoxy-D-glucono-1,5-lactone + [(1->4)-N-acetyl-beta-D-glucosaminyl]n + acceptor + H2O
Comment(s)
The enzyme cleaves chitin in an oxidative manner, releasing fragments of chitin with an N-acetylamino-D-glucono-1,5-lactone at the reducing end. The initially formed lactone at the reducing end of the shortend chitin chain quickly hydrolyzes spontaneously to the aldonic acid. In vitro ascorbate can serve as reducing agent.
Cross-references
BRENDA	1.14.99.53
EC2PDB	1.14.99.53
ExplorEnz	1.14.99.53
KEGG Ligand Database for Enzyme Nomenclature	1.14.99.53
IUBMB Enzyme Nomenclature	1.14.99.53
MEDLINE	Find literature relating to 1.14.99.53
MetaCyc	1.14.99.53
Rhea expert-curated reactions	1.14.99.53
UniProtKB/Swiss-Prot	Q838S1, LCHMO_ENTFA A3KIM2, LCHMO_STRA7

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