enzyme.expasy.org

ENZYME - 3.3.2.12 oxepin-CoA hydrolase

Accepted Name
oxepin-CoA hydrolase
Reaction catalysed
2-oxepin-2(3H)-ylideneacetyl-CoA + H2O = 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde
Comment(s)
  • The enzyme from Escherichia coli is a bifunctional fusion protein that also catalyzes EC 1.17.1.7.
  • Combined the two activities result in a two-step conversion of oxepin-CoA to 3-oxo-5,6-dehydrosuberyl-CoA, part of an aerobic phenylacetate degradation pathway.
  • The enzyme from Escherichia coli also exhibits enoyl-CoA hydratase activity utilizing crotonyl-CoA as a substrate.
  • Formerly EC 3.7.1.16.
Cross-references
BRENDA3.3.2.12
EC2PDB3.3.2.12
ExplorEnz3.3.2.12
PRIAM enzyme-specific profiles3.3.2.12
KEGG Ligand Database for Enzyme Nomenclature3.3.2.12
IUBMB Enzyme Nomenclature3.3.2.12
IntEnz3.3.2.12
MEDLINEFind literature relating to 3.3.2.12
MetaCyc3.3.2.12
Rhea expert-curated reactions3.3.2.12
UniProtKB/Swiss-Prot

P77455, PAAZ_ECOLI

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.3.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-