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ENZYME - 4.4.1.19 phosphosulfolactate synthase

Accepted Name
phosphosulfolactate synthase
Alternative Name(s)
(2R)-phospho-3-sulfolactate synthase
PSL synthase
Reaction catalysed
(2R)-O-phospho-3-sulfolactate = phosphoenolpyruvate + sulfite + H(+)
Comment(s)
  • The enzyme from Methanococcus jannaschii catalyzes the Michael addition of sulfite to phosphoenolpyruvate.
  • It specifically requires phosphoenolpyruvate and its broad alkaline pH optimum suggests that it uses sulfite rather than hydrogensulfite.
Cross-references
BRENDA4.4.1.19
EC2PDB4.4.1.19
ExplorEnz4.4.1.19
KEGG Ligand Database for Enzyme Nomenclature4.4.1.19
IUBMB Enzyme Nomenclature4.4.1.19
MEDLINEFind literature relating to 4.4.1.19
MetaCyc4.4.1.19
Rhea expert-curated reactions4.4.1.19
UniProtKB/Swiss-Prot
O06739, PSLS_BACSUQ57703, PSLS_METJAO27710, PSLS_METTH
Q9AF21, PSLS_XANP2

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.4.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-