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MDM2 promotes genome instability b ... | Article | H1 Connect

Evaluations

Genome instability is frequently observed in cancer cells. This study demonstrated that MDM2 influences sarcomagenesis through ubiquitination and proteasomal degradation of P53 and other proteins such as HBP1, establishing MDM2 as a key player in genomic instability.

This Recommendation is of an article referenced in a Faculty Review also written by Richard Riedel.

Relevant Specialties

  • Bioinformatics, Biomedical Informatics & Computational Biology

    Genomics

  • Biotechnology

    Genomics | Medical Genetics

  • Cancer Biology

    Cancer Genomes & Epigenomes | Cell Growth & Division

  • Cell Biology

    Cell Growth & Division | Control of Gene Expression

  • Genomics & Genetics

    Cancer Genomes & Epigenomes | Control of Gene Expression | Genomics | Medical Genetics

  • Molecular Biology

    Control of Gene Expression

  • Molecular Medicine

    Cell Growth & Division | Medical Genetics

  • Oncology

    Cancer Genomes & Epigenomes | Sarcomas

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