Exosomes in the tumor microenvironment of sarcoma: from biological functions to clinical applications - Journal of Nanobiotechnology
- ️Min, Li
- ️Mon Sep 05 2022
MFS
Serum
miR-1260b
15 patients, 5 non-sarcoma patients, 9 healthy controls
Diagnostic biomarker
[67]
DSRCT
Serum
miR-34a-5p, miR-22-3p, miR-324-5p
3 patients, 4 healthy controls
Diagnostic biomarker
[74]
OS
Serum
miR-195-3p
25 patients, 10 healthy controls
Diagnostic biomarker
[77]
OS
Serum
miRNAs
5 patients
Diagnostic biomarker
[78]
DDLPS
Serum, tissue
miR-1246, -4532, -4454, -619-5p, and -6126
22 OS, 17 DDLPS, 3 EWS patients
Diagnostic biomarker
[79]
SS
Serum
miR-92b-3p
12 SS patients, 12 benign tumor patients, 12 healthy controls
Diagnostic biomarker
[80]
RTK
Serum
miR-214-3p
10 patients, 10 healthy controls
Diagnostic biomarker
[81]
OS
Serum
Proteins
8 patients, 5 controls with fracture, 5 healthy controls
Diagnostic biomarker
[83]
EWS
Serum
CD99/MIC2, NGFR
10 patients, 6 healthy controls
Diagnostic biomarker
[84]
GIST
Serum
KIT, SPRY4
9 patients, 9 healthy controls
Diagnostic and prognostic biomarker
[85]
OS
Serum
PD-L1, N-cadherin
70 OS patients, 9 benign tumor patients, 22 healthy controls
Diagnostic biomarker
[86]
OS
Serum
Proteins
20 lung metastasis patients, 20 non-metastasis patients, 12 healthy controls
Diagnostic biomarker
[87]
ARMS, SS
Serum
Fusion transcripts
65 ARMS patients, 15 SS patients
Diagnostic biomarker
[89]
OS
Serum, tissue
lncRNA CASC15
Sera from 5 patients and healthy controls; 30 OS specimens, 30 normal bone tissues
Diagnostic biomarker
[90]
OS
Serum
hsa-circ-103801
43 patients, 5 healthy controls
Prognostic biomarker, chemoresistance↑
[91]
OS
Tissue
lncRNA SNHG17
5 pairs of tumor and tumor-free tissues
Prognostic biomarker
[75]
OS
Serum, tissue
miR-25-3p
Sera from 10 patients and 10 healthy controls; 45 biopsy specimens
Prognostic and diagnostic biomarker
OS
Serum, tissue
SENP1
Sera from 146 patients; 60 pairs of tumor and tumor-free tissues
Prognostic biomarker
[92]
OS
Serum
Alpha-2-macroglobulin, protein S, complement C2
\
Prognostic biomarker, chemoresistance↑
[94]
OS
Serum
lncRNA ANCR
10 patients, 10 chemosensitive controls
Prognostic biomarker, chemoresistance↑
[95]