The art of cellular communication: tunneling nanotubes bridge the divide - Histochemistry and Cell Biology
- ️Gerdes, Hans-Hermann
- ️Wed Apr 02 2008
Cell type | TNT-like structures | ||
|---|---|---|---|
Cytoskeletal components | Membrane continuity/ “open-ended” | Cargo | |
PC12 cells (Rustom et al. 2004) | F-actin, myosin Va | (+)b | Endosome-related organelles, lipid-anchored proteins (EGFP-f), EGFP-actin |
NRK cells (Rustom et al. 2004)c | (F-actin, myosin Va)c | ND | Endosome-related organelles |
EBV-transformed human B cell line (721.221) (Önfelt et al. 2004) | ND | ND | GPI-GFP, (HLA-Cw6-GFP, in coculture with human peripheral blood Natural Killer cells)d |
Between neonatal rat CM and adult human EPC (Koyanagi et al. 2005) | ND | ND | Mitochondria, soluble proteins (GFP) |
Primary cultures of rat astrocytes (Zhu et al. 2005) | F-actin, myosin Va | ND | ND |
DC (Watkins and Salter 2005) | ND | (+)e | Calcium fluxes, surface receptors (HLA-A,B,C class I MHC)d |
THP-1 monocytes (Watkins and Salter 2005) | F-actin | (+)e | Calcium fluxes, the fluid phase marker lucifer yellow, surface receptors (HLA-A,B,C class I MHC)d |
Between DC and THP-1 monocytes (Watkins and Salter 2005) | ND | (+)e | Calcium fluxes |
Human monocyte-derived macrophages (bridges with diameter ≥0.7 μm) (Önfelt et al. 2006) | F-actin, microtubules | (+)f | Mitochondria, endosome-related organelles, lysosomes |
Human monocyte-derived macrophages (nanotubes with diameter <0.7 μm) (Önfelt et al. 2006) | F-actin | ND | Surfing Mycobacterium bovis bacillus Calmette-Guérin |
Cos-1, XC and HEK 293 cells (Sherer et al. 2007) | F-actin | (−)b | MLV |
Jurkat T cells (Sowinski et al. 2008) | F-actin | (−)b,e | HIV-1 protein Gag |