4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration - Acta Neuropathologica

• 20 November 2019

  The original version of this article unfortunately contained a mistake. The Panel A in the published figure 5 is incorrect. The corrected Figure 5 is placed in the following page.

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Authors and Affiliations

1. LPVD, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT, USA

   Eri Saijo, Michael A. Metrick II, Allison Kraus & Byron Caughey

2. Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA

   Shunsuke Koga & Dennis W. Dickson

3. IRCCS Istituto delle Scienze Neurologiche di Bologna, 40139, Bologna, Italy

   Piero Parchi & Marcello Rossi

4. Department of Experimental Diagnostic and Specialty Medicine (DIMES), University of Bologna, 40138, Bologna, Italy

   Piero Parchi

5. Department of Neurosciences, Parkinson and Other Movement Disorders Center, University of California, San Diego, CA, USA

   Irene Litvan

6. Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA, USA

   Salvatore Spina, Adam Boxer, Julio C. Rojas, Lea T. Grinberg & William W. Seeley

7. Department of Neurosciences, University of California, San Diego, CA, USA

   Douglas Galasko

8. Indiana University School of Medicine, Indianapolis, IN, USA

   Kathy Newell & Bernardino Ghetti

9. University of Verona, Verona, Italy

   Gianluigi Zanusso

10. Department of Pathology, LIM-22, University of Sao Paulo, Sao Paulo, Brazil

    Lea T. Grinberg

Contributions

ES and BC conceived the overall project. ES and MAM designed, performed, and interpreted the primary experiments. ES developed the 4R RT-QuIC assays for brain and CSF. MAM helped to optimize the assay for brain tissue. MAM developed and performed the ATR-FTIR-based tau conformer subtyping. SK, PP, IL, SS, AB, MR, KN, GZ, LTG, WWS, BG, DG, and DWD provided tissue and/or fluid specimens and key clinical and neuropathological information, insights, and interpretations. AK, ES, MAM, and BC performed and/or interpreted electron microscopy analyses. ES, MAM, and BC prepared the manuscript. All authors helped to interpret the results and edit the manuscript.

Corresponding author

Correspondence to Byron Caughey.

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Eri Saijo and Michael A. Metrick II are co-first authors.