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How best to identify chromosomal interactions: a comparison of approaches. - ORA - Oxford University Research Archive

  • ️Tue Jan 31 2017

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Abstract:

Chromosome conformation capture (3C) methods are central to understanding the link between nuclear structure and function, and the physical interactions between distal regulatory elements and promoters. However, no one method is appropriate to address all biological questions, as each variant differs markedly in resolution, reproducibility, throughput and biases. A thorough appreciation of the strengths and weaknesses of each technique is critical when choosing the correct method for a specif...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors

+ Davies, J More by this author

Institution:

University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Role:
Author

+ Higgs, D More by this author

Institution:

University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Role:
Author

+ Hughes, J More by this author

Institution:

University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Role:
Author

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Bibliographic Details

Item Description

Language:

English

Subjects:
Pubs id:
UUID:

uuid:c233180b-e4a2-4288-b022-95549eb90d84

Local pid:

pubs:679684

Source identifiers:
Deposit date:

2017-06-22

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