CN104288748A - Traditional Chinese medicinal preparation for treating neurasthenia and preparation method thereof - Google Patents
- ️Wed Jan 21 2015
Info
-
Publication number
- CN104288748A CN104288748A CN201410621647.6A CN201410621647A CN104288748A CN 104288748 A CN104288748 A CN 104288748A CN 201410621647 A CN201410621647 A CN 201410621647A CN 104288748 A CN104288748 A CN 104288748A Authority
- CN
- China Prior art keywords
- parts
- radix
- rhizoma
- chinese medicine
- preparation Prior art date
- 2014-11-07 Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/285—Aucklandia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8884—Arisaema, e.g. Jack in the pulpit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/89—Cyperaceae (Sedge family)
- A61K36/8905—Cyperus (flatsedge)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8998—Hordeum (barley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicinal composition for treating neurasthenia and a preparation method thereof. The traditional Chinese medicinal composition is prepared by mixing pinellia ternata, dried orange peel, poria cocos, bamboo shaving, arisaema, immature bitter orange, elecampane, rhizoma cyperi, radix curcumae, radix bupleuri, raw white atractylodes rhizome, fried malt, dens draconis, raw liquorice and ginger according to a certain weight proportion, has the effects of drying dampness and promoting urination, and tranquilizing and calming the mind and can effectively treat the neurasthenia.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to one and treat neurasthenic Chinese medicine composition.The invention still further relates to the preparation method of this Chinese medicine preparation.
Background technology
Neurasthenia has another name called neurasthenic neurosis, belongs to the one of mental illness, be a class spirit easily excited and mental easily tired, to be often in a bad mood the neurosis disorder of worry and psychology physiological symptom.Neurasthenia's main manifestations is the imbalance of brain higher nervous activity, is characterized in often feeling mental and being short of physical strength, fatiguability, and work efficiency is low, but exists without organic disease.Can occur clinically being variously not suitable with symptom, as dizzy, feel dizzy, sore waist and aching in the waist and the back, irritable, difficulty falling asleep, dreaming often and waking easily, insomnia forgetfulness, premature ejaculation sexual impotence, can with minor depressive or anxiety.Data shows, work, study hypertonicity are acted hurriedly in a messy situation, have a rest and sleep irregular, operating pressure is large, and health is in subhealth state, and feels have burden and offending emotion etc., cause neurasthenic principal element, the lighter affects work and study, and severe one is lost interest in surrounding, has world-weary thought.
This name of disease of neurasthenia is not had in Chinese medicine, but according to the clinical main manifestations of patient neurasthenia as sleep disorder, hypomnesis, anxiety, agitation, nervous, dizzy etc., neurasthenia belongs to the category such as " forgetful ", " palpitation with a distress feeling ", " being insomnia ", " headache ", " deficient " of Chinese medicine.The main symptom " insomnia " of Huangdi's Internal Classics to primary disease has to be discussed clearly." the large puzzled opinion of Ling Shu Miraculous Pivot or Divine Axis " discusses the pathogenesis of " unable to close the eyes " in more detail, thinks that " defending gas must not people Yu Yin, often stays in sun.Stay in sun that then yang-energy is full, yang-energy completely then sun lifts up Sheng; Must not people in the moon then cloudy deficiency of vital energy, therefore the unable to close the eyes." propose the neurasthenic main symptoms such as insomnia, be caused by imbalance of YIN and YANG.Be insomnia with the passing of time, visceral dysfunction.Its concentrated reflection is in the heart, liver, spleen, lung, all dirty functional disorders of kidney.Therefore the five internal organs are become estranged, vital essence blood deficiency is its Etiological pathogenesis, wherein especially close with heart kidney relation.
Current western medical treatment neurasthenia mainly relies on the hypnotic sedative dose of treatments such as stable, but these medicines existing defects in safety and dependency, side effect is larger, easily produces additive and drug resistance, should not take for a long time.In recent years, Chinese medicine obtains obvious curative effects in treatment neurasthenia, and side effect is little, and Chinese medicine has wide prospect in the neurasthenic research for the treatment of.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition, this Chinese medicine composition has evident in efficacy for treatment neurasthenia, rapid-action, the feature had no side effect.
The present invention selects the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Poria, Caulis Bambusae In Taenia, Arisaema Cum Bile, Fructus Aurantii Immaturus, the Radix Aucklandiae, Rhizoma Cyperi, Radix Curcumae, Radix Bupleuri, Rhizoma Atractylodis Macrocephalae, Fructus Hordei Germinatus (parched), Dens Draconis, Radix Glycyrrhizae, Rhizoma Zingiberis Recens to combine, each efficacy of drugs is made by these drug regimens to produce synergism, make it that there is dampness diuretic, effect of tranquillizing and allaying excitement, thus effectively can treat neurasthenia.
The effect of Chinese medicine of the present invention:
Wherein:
The Rhizoma Pinelliae: be the tuber at the Rhizoma Arisaematis section plant Rhizoma Pinelliae (Pinellia ternata (Thunb.) Breit.).Nature and flavor are pungent, warm; Poisonous.Return spleen, stomach, lung meridian.Effect: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.The pungent loose warm-dryness syndrome of these product is poisonous, main enter taste double enter lung, water of manageing it wets, lowering the adverse flow of QI, and kind taste damp-phlegm of dispelling.Water is wet to be gone, and the strong and sputum of spleen is from disappearing, and inverse gas falls then harmonization of the stomach and feeling of fullness vomiting from only, therefore is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the good medicine of dissolving lump and resolving mass.Both cure mainly the abundant expectoration cough with asthma QI rising in reverse order of spleen damp-phlegm heap soil or fertilizer over and around the roots, control again the dizzy palpitation and insomnia that damp-phlegm is violated.
Pericarpium Citri Reticulatae: be the dry mature skin of rutaceae orange Citrus reticulata Blanco and variety thereof.Nature and flavor temperature, pungent, bitter.Enter spleen channel, stomach warp, lung meridian.Effect: regulating qi-flowing for strengthening spleen, in tune, dampness, reduces phlegm.Pericarpium Citri Reticulatae decoct and alcohol extract have excitation to heart, and larger dose has inhibitory action.Pericarpium Citri Reticulatae and the Rhizoma Pinelliae, again can warming for resolving cold-phlegm with can drying dampness to eliminate phlegm.
Poria: be the dry sclerotia of On Polyporaceae Poria Poria cocos (Schw.) Wolf.Nature and flavor are sweet, light, flat.GUIXIN, lung, spleen, kidney channel.Effect: eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming.Poria decoct has obvious sedation." modality ": " cure mainly Ji Rou Shun muscle of throbbing with fear cautious, dizziness agitation is controlled on side." this product is by heart-spleen boosting and tranquilizing mind.Be used for deficiency of both the heart and spleen, the irritability of insufficiency of vital energy and blood.
Caulis Bambusae In Taenia: be the dry intermediate layer of the stem stalk of grass bambusa breviflora Munro Bambusa tuldoides Munro, major part allusion quotation bamboo Sinocalamus beecheyanus (Munro) McClure var. pubescens P. F. Li or phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle Phyllostachys nigra (Lodd.) Munro var. henonis (Mitf.) Stapf ex Rendle.Nature and flavor are slightly cold, sweet.Attach to the lung and stomach meridians.Effect: clearing away heat to stop vomiting, clearing away phlegm dissipating depression of QI.Caulis Bambusae In Taenia and the Rhizoma Pinelliae, two medicines all have reduce phlegm, preventing or arresting vomiting, sedative action, peaceful for the unhappiness caused by milk-livered expectorant heat stagnation knot, have a dizzy spell, card that the sound of vomiting is vomitted in regurgitation, often refinforce each other, reduce phlegm to work in coordination with, calm the nerves, preventing or arresting vomiting effect.
Arisaema Cum Bile: for the fine powder of Rhizoma Arisaematis (processed) and cattle, sheep or Fel Sus domestica process from strand, or form through fermentation processing for Arisaema Cum Bile fine powder and cattle, sheep or Fel Sus domestica.Nature and flavor bitter cold, micro-pungent, cool.Return lung, liver, spleen channel.Effect: removing heat-phlegm, dispelling wind and relieving convulsion." book on Chinese herbal medicine converge with speech ": " Rhizoma Arisaematis, forefathers with Fel Bovis seu Bubali system it, name says Arisaema Cum Bile.Fel Bovis seu Bubali bitter cold and moistening, has the merit that the liver benefiting is relieving convulsion, star processed dry and make not malicious." this product can control middle wind-phlegm fan, infantile convulsion epilepsy, and phlegm-fire is breathed heavily and coughed, phlegm-accumulating vertigo.
Fructus Aurantii Immaturus: be the dry young fruit of rutaceae Citrus aurantium Linn. Citrus aurantium L. and variety or Fructus Citri sinensis Citrus sinensis Osbeck.Nature and flavor bitter, acrid, cold.Return spleen, stomach, liver, heart channel.Effect: dispelling the stagnated QI removing food stagnancy, loose painful abdominal mass of reducing phlegm.Furctus Aurantii Immaturus extract has obvious sedation.
The Radix Aucklandiae: be the dry root of feverfew Radix Aucklandiae Aucklandia lappa Decne..Nature and flavor are pungent, bitter, temperature.Return spleen, stomach, liver, lung meridian.Effect: regulate the flow of vital energy in adjusting, drying dampness to eliminate phlegm, promoting the circulation of QI to relieve pain, for breast gastral cavity distending pain, heavy after dysentery, food stagnation does not disappear, anorexia.
Rhizoma Cyperi: be the dry rhizome of sedge dried tuber Cyperus rotundus L..Pungent, the micro-hardship of nature and flavor, sweet, flat.Enter liver, tri-jiao channel.Effect: resolving depression of regulating the flow of vital energy, pain relieving.Rhizoma Cyperi volatile oil has obvious syngignoscism." the southern regions of the Yunnan Province book on Chinese herbal medicine ": adjust the gas in blood, dissipating depression of QI, alleviating distention in middle-JIAO, helps digestion.
Radix Curcumae: be the dried root of zingiberaceous plant RADIX CURCUMAE Curcuma wenyujin Y. H. Chen et C. Ling, Rhizoma Curcumae Longae Curcuma longa L., Guangxi zedoary Curcuma kwangsiensis S. G. Lee et C. F. Liang or Rhizoma Curcumae Curcuma phaeocaulis Val..Nature and flavor are pungent, bitter, cold.Return liver, the heart, lung meridian.Effect: promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, clear away heart-fire removing heat from blood, promoting the function of the gallbladder to alleviate jaundice.Cure mainly: all pains of breast abdomen side of body rib, lose the heart demented, calentura coma.The pungent loose hardship of this product is let out, heat clearing away cold in nature, can have one's ideas straightened out by heart fire-clearing upset-relieving.
Radix Bupleuri: be Umbelliferae herbaceos perennial Radix Bupleuri Bupleurum chinense DC.(Radix Bupleuri) or Radix Bupeuri Scorzonerfolii. Bupleurum scorzonerifolium Willd.(Radix Bupleuri Scorzonerifolii) root or herb.Nature and flavor are slightly cold, bitter, pungent.Return liver, lung, spleen channel.Effect: expelling pathogenic factors from the exterior expels the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy." medicineization justice ": Radix Bupleuri, property is gently clear, and main liter falls apart, mildly bitter flavor, main soothing the liver." book on Chinese herbal medicine through separate ": " Radix Bupleuri, stagnation of QI person in its main trusted subordinate's the intestines and stomach, trusted subordinate's the intestines and stomach, five hide six mansions also, and Zang Fu totally ten two warps; all 11 hide and all depend on gallbladder, and Radix Bupleuri is gently clear, and rise and reach courage, courage bar reaches; then 11 hide from Xuanhua, therefore in trusted subordinate's the intestines and stomach, all have stagnation of QI, all can fall apart also.Its main diet accumulator, lid diet enters stomach, the spleen transporting essential substances to the liver, the evacuation of liver, borrow again few positive gallbladder be the master of hair growth promoting also, Radix Bupleuri liter reaches courage, then liver can fall apart essence, and diet gathers from lower.Shaoyang channel row half exterior and half interior, few sun, by evil, evilly also then to be trembled with fear in the moon, evil and in Yang Zere, Radix Bupleuri treating SHAO YANG disease by mediation, therefore the pathogen of main cold and heat also." pharmaceutical research Radix Bupleuri just has obvious sedation agents.
Rhizoma Atractylodis Macrocephalae: be the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..Nature and flavor are bitter, sweet, temperature.Return spleen, stomach warp.Effect: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis.In the sweet temperature compensation of the Rhizoma Atractylodis Macrocephalae, can air making-up and spleen enlivening, also can strengthening superficial resistance to stop perspiration, and the Radix Astragali, Radix Pseudostellariae compatibility, play the merit of spleen reinforcing lung altogether.To rule together asthenia, the weak person of overstrain.
Fructus Hordei Germinatus (parched): for the mature fruit of grass Fructus Hordei Vulgaris Hordeum vulgare L. is through germinateing drying and obtaining.Nature and flavor are sweet, flat.Return spleen, stomach warp, Liver Channel.Effect: promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite.
Dens Draconis: for ancient times mammal as if the fossil of tooth of class, rhinoceros class, Hippocampal cortex etc.Nature and flavor are puckery, sweet, cool.GUIXIN, Liver Channel enter the heart, liver, kidney, large intestine channel.Effect: tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Control infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, and seminal emission stranguria with turbid discharge, tells nosebleed and have blood in stool.
Radix Glycyrrhizae: be the dry root and rhizome of glycyrrhizic legume lycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. lycyrrhiza Inflata Bat. or Glycyrrhiza glabra L. lycyrrhiza labra L..Nature and flavor are sweet, flat.GUIXIN, lung, spleen, stomach warp.Effect: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription." Japan hanako materia medica ": peace soul determines soul.Mend five kinds of strain and seven kinds of impairment, all be deficient, palpitation with fear, unhappy, forgetful.Logical nine orifices, sharp hundred arteries and veins, beneficial intensive culture gas, strengthening bone and muscle, separates cold and hot.
Rhizoma Zingiberis Recens: be the fresh rhizome of zingiber Zingiber officinale Rosc..Nature and flavor are pungent, tepor.Return lung, spleen, stomach warp.Effect: relieving the exterior syndrome by diaphoresis, warming middle-JIAO to arrest vomiting, warming the lung to relieve cough.Solving toxin of fish and crab, separates poison of drug.Especially for fish Eriocheir sinensis poison, the drug intoxication such as the Rhizoma Pinelliae, Rhizoma Arisaematis has Detoxication.Rhizoma Zingiberis Recens can act on sympathetic nerve and vagal system, and have the effect suppressing stomach function and direct excited pipe smooth muscle, Rhizoma Zingiberis Recens has inhibitory action to central nervous system.
Side's solution of the present invention is: Rhizoma Pinelliae drying dampness to eliminate phlegm in side, Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, Poria eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, Caulis Bambusae In Taenia clearing away heat to stop vomiting, clearing away phlegm dissipating depression of QI, above four tastes are monarch drug altogether, Pericarpium Citri Reticulatae joins Rhizoma Pinelliae invigorating the spleen and benefiting QI, drying dampness to eliminate phlegm water is wet goes, and spleen is strong and sputum disappears certainly, control the dizzy palpitation and insomnia that damp-phlegm is violated, Poria and Caulis Bambusae In Taenia energy heart-spleen boosting and tranquilizing mind, fundamentally stable people's emotion, insomnia phenomenon can take a turn for the better gradually, also can be happy along with mood, so circulate benignly, then have a sleepless night, nervous phenomenon can fade away.Arisaema Cum Bile dispelling wind and relieving convulsion, Fructus Aurantii Immaturus dispelling the stagnated QI removing food stagnancy, to reduce phlegm loose painful abdominal mass, during Muxiangliqi is adjusted, drying dampness to eliminate phlegm, Rhizoma Cyperi is regulated the flow of vital energy resolving depression, Radix Curcumae promoting QI circulation for relieving depression, clear away heart-fire removing heat from blood, the above five tastes are ministerial drug altogether, assist a ruler in governing a country monarch drug dampness diuretic on the one hand, invigorating the spleen and benefiting QI, with tranquilizing mind, help hypnosis, on the other hand, promote qi circulation digestion promoting, to regulate the flow of vital energy resolving depression, patient's appetite can be promoted, increase the food-intake of patient, to maintain the normal function of health, pick body, promote again the improvement of the state of an illness further, Radix Bupleuri dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy, Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI, dampness diuretic, Fructus Hordei Germinatus (parched) promote qi circulation digestion promoting, Dens Draconis tranquillizing the mind by relieving convulsion, Radix Glycyrrhizae invigorating the spleen and replenishing QI, Rhizoma Zingiberis Recens warming middle-JIAO to arrest vomiting, a few taste is adjuvant drug altogether above, not only assist monarch drug medicine to strengthen calmness, sleeping, digestant effect, and Radix Glycyrrhizae, Rhizoma Zingiberis Recens can detoxify, reduce the toxic action that medicine is unnecessary, Radix Glycyrrhizae also has coordinating the actions of various ingredients in a prescription, priming return through effect, have the effect making medicine concurrently.The all medicines of this side share, and the monarch and his subjects pull together, and assistant makes auxiliary altogether, has dampness diuretic, effect of tranquillizing and allaying excitement, effectively can treat neurasthenia.
Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, and each raw material dosage is for all to have good curative effect in following weight parts scope: Rhizoma Pinelliae 7-17 part, Pericarpium Citri Reticulatae 7-17 part, Poria 10-20 part, Caulis Bambusae In Taenia 10-20 part, Arisaema Cum Bile 7-17 part, Fructus Aurantii Immaturus 10-20 part, Radix Aucklandiae 7-17 part, Rhizoma Cyperi 10-20 part, Radix Curcumae 10-20 part, Radix Bupleuri 10-20 part, Rhizoma Atractylodis Macrocephalae 20-28 part, Fructus Hordei Germinatus (parched) 10-20 part, Dens Draconis 40-60 part, Radix Glycyrrhizae 3-9 part, Rhizoma Zingiberis Recens 6-12 part.
Wherein be preferably: the Rhizoma Pinelliae 12 parts, Pericarpium Citri Reticulatae 12 parts, 15 parts, Poria, Caulis Bambusae In Taenia 15 parts, Arisaema Cum Bile 12 parts, Fructus Aurantii Immaturus 15 parts, the Radix Aucklandiae 12 parts, Rhizoma Cyperi 15 parts, Radix Curcumae 15 parts, Radix Bupleuri 15 parts, Rhizoma Atractylodis Macrocephalae 24 parts, Fructus Hordei Germinatus (parched) 15 parts, Dens Draconis 50 parts, Radix Glycyrrhizae 6 parts, 9 parts, Rhizoma Zingiberis Recens.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations, as pill, powder, tablet, oral liquid etc.Such as these crude drug pulverize mix homogeneously can be made powder to take after mixing it with water; Can decocting be used, obtain filtrate after filtration, add antiseptic and make oral liquid; Also directly decoction can be taken if desired.
The preferred dosage form of the present invention is decoction, and its preparation method is as follows:
Step one, first weigh Dens Draconis according to weight proportion and first put into crucible and calcine, to being popular in, taking out, cooling, pulverize grinding together with Poria, Fructus Hordei Germinatus (parched), cross 120 mesh sieves, for subsequent use;
Step 2, to weigh the Radix Aucklandiae according to weight proportion, Rhizoma Cyperi, Radix Curcumae, Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis Recens put into marmite, add the water of 8 times of volumes, first with high heat decocting is opened, then slow fire is transferred to, decoct 1 hour, then add the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Caulis Bambusae In Taenia, Fructus Aurantii Immaturus, Radix Bupleuri, Radix Glycyrrhizae put into pot and decoct 0.5 hour, filter, obtain filtrate, for subsequent use;
Step 3: a kind of for step gained powder is mixed in medicine soup, stirs while hot, both decoction of the present invention.
Medicine of the present invention has dampness diuretic, the effects such as tranquillizing and allaying excitement, and evident in efficacy, rapid-action, has no side effect, and according to clinical 100 routine patient view statistics, uses medicine of the present invention the total effective rate course for the treatment of 85%, two the total effective rate course for the treatment of 96%.
Detailed description of the invention
Embodiment one, the Rhizoma Pinelliae 7 parts, Pericarpium Citri Reticulatae 7 parts, 10 parts, Poria, Caulis Bambusae In Taenia 10 parts, Arisaema Cum Bile 7 parts, Fructus Aurantii Immaturus 10 parts, the Radix Aucklandiae 7 parts, Rhizoma Cyperi 10 parts, Radix Curcumae 10 parts, Radix Bupleuri 10 parts, Rhizoma Atractylodis Macrocephalae 20 parts, Fructus Hordei Germinatus (parched) 10 parts, Dens Draconis 40 parts, Radix Glycyrrhizae 3 parts, 6 parts, Rhizoma Zingiberis Recens.
Embodiment two, the Rhizoma Pinelliae 12 parts, Pericarpium Citri Reticulatae 12 parts, 15 parts, Poria, Caulis Bambusae In Taenia 15 parts, Arisaema Cum Bile 12 parts, Fructus Aurantii Immaturus 15 parts, the Radix Aucklandiae 12 parts, Rhizoma Cyperi 15 parts, Radix Curcumae 15 parts, Radix Bupleuri 15 parts, Rhizoma Atractylodis Macrocephalae 24 parts, Fructus Hordei Germinatus (parched) 15 parts, Dens Draconis 50 parts, Radix Glycyrrhizae 6 parts, 9 parts, Rhizoma Zingiberis Recens.
Embodiment three, the Rhizoma Pinelliae 17 parts, Pericarpium Citri Reticulatae 7 parts, 20 parts, Poria, Caulis Bambusae In Taenia 20 parts, Arisaema Cum Bile 17 parts, Fructus Aurantii Immaturus 20 parts, the Radix Aucklandiae 17 parts, Rhizoma Cyperi 20 parts, Radix Curcumae 20 parts, Radix Bupleuri 20 parts, Rhizoma Atractylodis Macrocephalae 28 parts, Fructus Hordei Germinatus (parched) 20 parts, Dens Draconis 60 parts, Radix Glycyrrhizae 9 parts, 12 parts, Rhizoma Zingiberis Recens.
Here is the clinical statistics data that patient uses medicine of the present invention:
One, physical data
Accept patient's totally 100 examples for medical treatment, wherein male 46 example, women 54 example, M-F 0.9:1,45 years old mean age.
Two, diagnostic criteria
1, weak or lasting significantly fatigue symptom.As often felt deficient in energy, dispirited, can not require mental skill, hypomnesis, mental retardation, in study and work, attention can not be concentrated, and work efficiency significantly goes down, can not banish the feeling of languor even if fully have a rest, general physical checkup again without physical disease, also without organic disease.
2, possess any two in following symptom simultaneously:
(1) easy excitement fatiguability again;
(2) anxious state of mind is large, when anything crops up passionnate, worries and nervous;
(3) because of nervous engender tension headache or myalgia;
(4) sleep disorder.Show as difficulty falling asleep, easily wake up with a start, dreaminess, heavy then dizzy, cardiopalmus, appetite decline.
3, above-mentioned situation causes harmful effect to study, work and social communication.
4, the course of disease is more than three months.
5, other neurosis and mental disorder is eliminated.
Three, Therapeutic Method
According to drug weight proportioning of the present invention, weighting raw materials (daily dose), decocting, filter and remove residue, sooner or later servicing once, 20th is a course for the treatment of.
Four, efficacy assessment standard
1. fully recover: clinical symptom disappearance, does not affect normal work and study;
2. effective: sleep quality improves, appetite increases, and the diseases such as headache, dizziness, fatigue and weak are taken a turn for the better, and memory increases;
3. effective: above-mentioned symptom makes moderate progress;
4. invalid: before and after treatment, clinical symptoms is unchanged.
Five, therapeutic outcome statistics
Wherein: total effective rate=cure rate+obvious effective rate+effective percentage
Shown by the statistics of therapeutic outcome, Chinese medicine of the present invention has good clinical effectiveness treatment neurasthenia, effectively can improve the cure rate for the treatment of, be worth promoting in clinical practice.
Model case and curative effect:
Case one, high certain, female, 18 years old, high school senior, examined readme and suffers from neurasthenia, because this semester brain overwork, have a rest bad, always insomnia and dreamful sleep, and mood constant tension, and almost cannot be absorbed in studies, therefore school grade also obviously declines.Feel now deficient in energy, dispirited.After patient adopts Chinese medicine of the present invention to take a course for the treatment of, sleep quality improves, and can normally learn, recovery from illness.
Case two, Ma, female, 36 years old age, examine state recent months often have a sleepless night, have a headache, dizzy, uncomfortable in chest, muscular soreness of whole body, attention cannot be concentrated, and work is greatly affected.After adopting Chinese medicine of the present invention to take two courses for the treatment of, sleep quality improves, and the symptoms such as headache, dizziness, muscular soreness of whole body take a turn for the better.
Case three, Zhang, man, 32 years old, evening, sleep did not have sleepiness to patient's readme over the past half year, fell asleep difficult, slept shallow, dreaminess, Yi Xing, regains consciousness after waking up and has difficulty in going to sleep, daytime, sleepy be can't fall asleep again, worried, anxiety and agitation for this reason, and with dizzy, headache, and the symptom such as nervous, uncomfortable in chest, gastrointestinal upset, can not work be adhered to, be disinclined to activity.After patient adopts Chinese medicine of the present invention to take two courses for the treatment of, symptom is significantly improved, effective.
Claims (4)
1. the neurasthenic Chinese medicine composition for the treatment of, it is characterized in that, this Chinese medicine composition is made up of the medicine of following weight portion: Rhizoma Pinelliae 7-17 part, Pericarpium Citri Reticulatae 7-17 part, Poria 10-20 part, Caulis Bambusae In Taenia 10-20 part, Arisaema Cum Bile 7-17 part, Fructus Aurantii Immaturus 10-20 part, Radix Aucklandiae 7-17 part, Rhizoma Cyperi 10-20 part, Radix Curcumae 10-20 part, Radix Bupleuri 10-20 part, Rhizoma Atractylodis Macrocephalae 20-28 part, Fructus Hordei Germinatus (parched) 10-20 part, Dens Draconis 40-60 part, Radix Glycyrrhizae 3-9 part, Rhizoma Zingiberis Recens 6-12 part.
2. the neurasthenic Chinese medicine composition of the treatment according to claims 1, it is characterized in that, be made up of the medicine of following weight portion: the Rhizoma Pinelliae 12 parts, Pericarpium Citri Reticulatae 12 parts, 15 parts, Poria, Caulis Bambusae In Taenia 15 parts, Arisaema Cum Bile 12 parts, Fructus Aurantii Immaturus 15 parts, the Radix Aucklandiae 12 parts, Rhizoma Cyperi 15 parts, Radix Curcumae 15 parts, Radix Bupleuri 15 parts, Rhizoma Atractylodis Macrocephalae 24 parts, Fructus Hordei Germinatus (parched) 15 parts, Dens Draconis 50 parts, Radix Glycyrrhizae 6 parts, 9 parts, Rhizoma Zingiberis Recens.
3. one according to claim 1 and 2 treats neurasthenic Chinese medicine preparation, it is characterized in that: described Chinese medicine preparation is decoction.
4. treat a preparation method for neurasthenic Chinese medicine preparation, it is characterized in that, preparation method is as follows: step one, first weigh Dens Draconis according to weight proportion and first put into crucible and calcine, to being popular in, taking out, cooling, pulverize grinding together with Poria, Fructus Hordei Germinatus (parched), cross 120 mesh sieves, for subsequent use; Step 2, to weigh the Radix Aucklandiae according to weight proportion, Rhizoma Cyperi, Radix Curcumae, Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis Recens put into marmite, add the water of 8 times of volumes, first with high heat decocting is opened, then slow fire is transferred to, decoct 1 hour, then add the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Caulis Bambusae In Taenia, Fructus Aurantii Immaturus, Radix Bupleuri, Radix Glycyrrhizae put into pot and decoct 0.5 hour, filter, obtain filtrate, for subsequent use; Step 3: gained powder in step one is mixed in medicine soup, stirs while hot, both decoction of the present invention.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410621647.6A CN104288748A (en) | 2014-11-07 | 2014-11-07 | Traditional Chinese medicinal preparation for treating neurasthenia and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410621647.6A CN104288748A (en) | 2014-11-07 | 2014-11-07 | Traditional Chinese medicinal preparation for treating neurasthenia and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN104288748A true CN104288748A (en) | 2015-01-21 |
Family
ID=52308859
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201410621647.6A Pending CN104288748A (en) | 2014-11-07 | 2014-11-07 | Traditional Chinese medicinal preparation for treating neurasthenia and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN104288748A (en) |
Citations (1)
* Cited by examiner, † Cited by third partyPublication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1840166A (en) * | 2006-01-11 | 2006-10-04 | 东莞市杏林春中医药研究所 | Wendan decoction modern traditional Chinese medicine oral preparation and production method thereof |
-
2014
- 2014-11-07 CN CN201410621647.6A patent/CN104288748A/en active Pending
Patent Citations (1)
* Cited by examiner, † Cited by third partyPublication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1840166A (en) * | 2006-01-11 | 2006-10-04 | 东莞市杏林春中医药研究所 | Wendan decoction modern traditional Chinese medicine oral preparation and production method thereof |
Non-Patent Citations (1)
* Cited by examiner, † Cited by third partyTitle |
---|
孙晓明等: "温胆汤治疗不寐症68例临床观察", 《天津中医》 * |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102283999B (en) | 2012-10-03 | Traditional Chinese medicine preparation for treating insomnia |
CN104146261B (en) | 2015-09-02 | Traditional Chinese medicine health care product of a kind of Woman climacteric and preparation method thereof |
CN104083740A (en) | 2014-10-08 | Internal traditional Chinese medicament for gaining weight |
CN102861228A (en) | 2013-01-09 | Traditional Chinese medicine composition for treating insomnia |
CN103127472B (en) | 2014-04-09 | Traditional Chinese medicine compound for refractory insomnia |
CN104069474A (en) | 2014-10-01 | Traditional Chinese medicine composition for treating seborrheic alopecia and preparation method thereof |
CN103908652A (en) | 2014-07-09 | Lavipeditum traditional Chinese medicine for treating insomnia and preparation method thereof |
CN104888152A (en) | 2015-09-09 | Traditional Chinese medicine preparation for treating postpartum depression and preparation method therefor |
CN115779064A (en) | 2023-03-14 | Astragalus root strengthening body resistance and preparation and application thereof |
CN104353051A (en) | 2015-02-18 | Traditional Chinese medicine preparation for treating stomachache and preparation method thereof |
CN104524479B (en) | 2018-05-25 | A kind of Chinese medicine composition for treating premenstrual syndrome and preparation method thereof |
CN103816456A (en) | 2014-05-28 | Pharmaceutical composition for treating post-traumatic brain syndrome |
CN107837343A (en) | 2018-03-27 | A kind of preparation method for alleviating kopiopia, the compound traditional Chinese medicine composite for the treatment of myopia and its pill |
CN104189867A (en) | 2014-12-10 | Traditional Chinese medicine composition for treating post-schizophrenic depression |
CN104547642A (en) | 2015-04-29 | Tradtional Chinese medicine composition for treating female fibromyalgia syndromes |
CN105012732B (en) | 2019-01-29 | Traditional Chinese medicine pill for treating sleep disorder syndrome and preparation method thereof |
CN104857372A (en) | 2015-08-26 | Drink for treating type 2 diabetes mellitus combined with hypertension and preparation method of drink |
CN110538288A (en) | 2019-12-06 | Intelligent system plaster for conditioning physique and preventing and treating diseases and preparation method thereof |
CN104017701A (en) | 2014-09-03 | Health wine capable of dredging five organs |
CN103989936A (en) | 2014-08-20 | Solution for conditioning sub-health and preparation method thereof |
CN103301403A (en) | 2013-09-18 | Chinese medicine composition for treating pain in terminal cancers |
CN102973900B (en) | 2013-12-11 | Traditional Chinese medicine composition for treating anxiety neurosis |
CN104288748A (en) | 2015-01-21 | Traditional Chinese medicinal preparation for treating neurasthenia and preparation method thereof |
CN106421113A (en) | 2017-02-22 | Traditional Chinese medicinal composition for prevention and external treatment of insomnia and using method of traditional Chinese medicinal composition |
CN105435083A (en) | 2016-03-30 | Capsule for postnatal depression |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
2015-01-21 | C06 | Publication | |
2015-01-21 | PB01 | Publication | |
2015-02-18 | C10 | Entry into substantive examination | |
2015-02-18 | SE01 | Entry into force of request for substantive examination | |
2018-11-02 | RJ01 | Rejection of invention patent application after publication | |
2018-11-02 | RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150121 |