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FR20C1046I1 - Influenza vaccines containing hemagglutinin and matrix proteins - Google Patents

  • ️Fri Nov 27 2020
US4060082A (en) 1976-08-16 1977-11-29 Mpl, Inc. Dual-ingredient medication dispenser SE8205892D0 (en) 1982-10-18 1982-10-18 Bror Morein IMMUNOGENT MEMBRANE PROTEIN COMPLEX, SET FOR PREPARATION AND USE THEREOF IL73534A (en) 1983-11-18 1990-12-23 Riker Laboratories Inc 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds US5916588A (en) 1984-04-12 1999-06-29 The Liposome Company, Inc. Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use US6090406A (en) 1984-04-12 2000-07-18 The Liposome Company, Inc. Potentiation of immune responses with liposomal adjuvants US4680338A (en) 1985-10-17 1987-07-14 Immunomedics, Inc. Bifunctional linker US5011828A (en) 1985-11-15 1991-04-30 Michael Goodman Immunostimulating guanine derivatives, compositions and methods US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant US4912094B1 (en) 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation JPH04500203A (en) 1988-08-25 1992-01-16 ザ リポソーム カンパニー,インコーポレイテッド Influenza vaccines and novel adjuvants US5238944A (en) 1988-12-15 1993-08-24 Riker Laboratories, Inc. Topical formulations and transdermal delivery systems containing 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine US4929624A (en) 1989-03-23 1990-05-29 Minnesota Mining And Manufacturing Company Olefinic 1H-imidazo(4,5-c)quinolin-4-amines HU212924B (en) 1989-05-25 1996-12-30 Chiron Corp Adjuvant formulation comprising a submicron oil droplet emulsion US4988815A (en) 1989-10-26 1991-01-29 Riker Laboratories, Inc. 3-Amino or 3-nitro quinoline compounds which are intermediates in preparing 1H-imidazo[4,5-c]quinolines US5658731A (en) 1990-04-09 1997-08-19 Europaisches Laboratorium Fur Molekularbiologie 2'-O-alkylnucleotides as well as polymers which contain such nucleotides US5741493A (en) * 1991-01-24 1998-04-21 Pasteur Merieux Serums Et Vaccins Vaccine composition against influenza, with synergic effects, containing influenza virus core as an additive EP0582581B1 (en) 1991-03-01 1999-05-06 Minnesota Mining And Manufacturing Company 1-SUBSTITUTED, 2-SUBSTITUTED 1H-IMIDAZO[4,5-c]QUINOLIN-4-AMINES US5389640A (en) 1991-03-01 1995-02-14 Minnesota Mining And Manufacturing Company 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines JPH0614756Y2 (en) 1991-06-26 1994-04-20 株式会社アルテ Assembled dual chamber syringe US5936076A (en) 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives US5268376A (en) 1991-09-04 1993-12-07 Minnesota Mining And Manufacturing Company 1-substituted 1H-imidazo[4,5-c]quinolin-4-amines US5266575A (en) 1991-11-06 1993-11-30 Minnesota Mining And Manufacturing Company 2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines MA22842A1 (en) 1992-03-27 1993-10-01 Smithkline Beecham Biolog PROCESS FOR THE PREPARATION OF VACCINE COMPOSITIONS. IL105325A (en) 1992-04-16 1996-11-14 Minnesota Mining & Mfg Immunogen/vaccine adjuvant composition PL170980B1 (en) 1992-06-25 1997-02-28 Smithkline Beecham Biolog Vaccine PL PL PL PL PL PL PL US5395937A (en) 1993-01-29 1995-03-07 Minnesota Mining And Manufacturing Company Process for preparing quinoline amines DE69405551T3 (en) 1993-03-23 2005-10-20 Smithkline Beecham Biologicals S.A. 3-0-DEAZYLATED MONOPHOSPHORYL LIPID A-CONTAINING VACCINE COMPOSITIONS DK0708772T3 (en) 1993-07-15 2000-09-18 Minnesota Mining & Mfg Imidazo [4,5-c] pyridin-4-amines US5352784A (en) 1993-07-15 1994-10-04 Minnesota Mining And Manufacturing Company Fused cycloalkylimidazopyridines US5762939A (en) 1993-09-13 1998-06-09 Mg-Pmc, Llc Method for producing influenza hemagglutinin multivalent vaccines using baculovirus WO1995011700A1 (en) 1993-10-29 1995-05-04 Pharmos Corp. Submicron emulsions as vaccine adjuvants GB9326174D0 (en) 1993-12-22 1994-02-23 Biocine Sclavo Mucosal adjuvant GB9326253D0 (en) 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines US6429199B1 (en) 1994-07-15 2002-08-06 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules for activating dendritic cells US6207646B1 (en) 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules US6239116B1 (en) 1994-07-15 2001-05-29 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules US5496284A (en) 1994-09-27 1996-03-05 Waldenburg; Ottfried Dual-chamber syringe & method AUPM873294A0 (en) 1994-10-12 1994-11-03 Csl Limited Saponin preparations and use thereof in iscoms US5482936A (en) 1995-01-12 1996-01-09 Minnesota Mining And Manufacturing Company Imidazo[4,5-C]quinoline amines GB9503863D0 (en) 1995-02-25 1995-04-19 Smithkline Beecham Biolog Vaccine compositions UA56132C2 (en) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Vaccine composition (variants), method for stabilizing qs21 providing resistance against hydrolysis (variants), method for manufacturing vaccine DE19612967A1 (en) 1996-04-01 1997-10-02 Behringwerke Ag Process for the propagation of influenza viruses in cell culture, and the influenza viruses obtainable by the process DE19612966B4 (en) * 1996-04-01 2009-12-10 Novartis Vaccines And Diagnostics Gmbh & Co. Kg MDCK cells and methods of propagating influenza viruses WO1998001174A1 (en) 1996-07-05 1998-01-15 Debiotech S.A. Dual-chamber syringe for mixing two substances prior to injection CA2283557A1 (en) 1997-03-10 1998-09-17 Heather L. Davis Use of nucleic acids containing unmethylated cpg dinucleotide as an adjuvant US6818222B1 (en) 1997-03-21 2004-11-16 Chiron Corporation Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants TW570803B (en) * 1997-04-09 2004-01-11 Duphar Int Res Influenza vaccine AU7126998A (en) 1997-04-16 1998-11-11 Connaught Laboratories Inc. Anti-influenza compositions supplemented with neuraminidase US6080725A (en) 1997-05-20 2000-06-27 Galenica Pharmaceuticals, Inc. Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof US5971953A (en) 1998-01-09 1999-10-26 Bachynsky; Nicholas Dual chamber syringe apparatus AU9785598A (en) 1997-10-03 1999-04-27 Texas Pharmaceuticals, Inc. Improved dual chamber syringe apparatus GB9725084D0 (en) 1997-11-28 1998-01-28 Medeva Europ Ltd Vaccine compositions PL354714A1 (en) 1998-04-09 2004-02-09 Smithkline Beecham Biologicals S.A. Adjuvant compositions EP1075276B1 (en) 1998-05-07 2007-10-17 Corixa Corporation Adjuvant composition and methods for its use US6562798B1 (en) 1998-06-05 2003-05-13 Dynavax Technologies Corp. Immunostimulatory oligonucleotides with modified bases and methods of use thereof US6110929A (en) 1998-07-28 2000-08-29 3M Innovative Properties Company Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof GB9817052D0 (en) 1998-08-05 1998-09-30 Smithkline Beecham Biolog Vaccine DE19835749C1 (en) 1998-08-07 2000-02-03 Dieter Perthes Ready-to-use syringe for unstable drugs US6544785B1 (en) 1998-09-14 2003-04-08 Mount Sinai School Of Medicine Of New York University Helper-free rescue of recombinant negative strand RNA viruses AT408615B (en) 1998-09-15 2002-01-25 Immuno Ag NEW INFLUENCE VIRUS VACCINE COMPOSITION PT1126876E (en) 1998-10-16 2007-04-30 Glaxosmithkline Biolog Sa Adjuvant systems and vaccines IL127331A0 (en) * 1998-11-30 1999-09-22 Yeda Res & Dev Peptide-based vaccine for influenza US20030130212A1 (en) 1999-01-14 2003-07-10 Rossignol Daniel P. Administration of an anti-endotoxin drug by intravenous infusion US6551600B2 (en) 1999-02-01 2003-04-22 Eisai Co., Ltd. Immunological adjuvant compounds compositions and methods of use thereof CA2361421A1 (en) 1999-02-03 2000-08-10 Biosante Pharmaceuticals, Inc. Therapeutic calcium phosphate particles and methods of manufacture and use ATE549032T1 (en) 1999-03-26 2012-03-15 Vical Inc ADJUVANCE COMPOUNDS FOR IMPROVEMENT OF IMMUNE RESPONSES TO POLYNUCLEOTIDE-BASED VACCINES DE122008000061I1 (en) 1999-04-06 2009-02-12 Wisconsin Alumni Res Found RECOMBINANT INFLUENZA VIRUSES FOR VACCINATION AND GENE THERAPY US6331539B1 (en) 1999-06-10 2001-12-18 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines EP1194580B2 (en) 1999-07-14 2010-08-25 Mount Sinai School of Medicine of New York University In vitro reconstitution of segmented negative-strand rna viruses HUP0203817A3 (en) 1999-09-24 2004-07-28 Smithkline Beecham Biolog Adjuvant comprising a polyxyethylene alkyl ether or ester and at least one nonionic surfactant KR20020038771A (en) 1999-09-24 2002-05-23 장 스테판느 Intranasal influenza virus vaccine KR20020038770A (en) 1999-09-24 2002-05-23 장 스테판느 Use of combination of polyoxyethylene sorbitan ester and octoxynol as adjuvant and its use in vaccines CN101543507A (en) 1999-09-25 2009-09-30 衣阿华大学研究基金会 Immunostimulatory nucleic acids GB9923176D0 (en) 1999-09-30 1999-12-01 Smithkline Beecham Biolog Novel composition US20010044416A1 (en) 2000-01-20 2001-11-22 Mccluskie Michael J. Immunostimulatory nucleic acids for inducing a Th2 immune response US6825036B2 (en) 2000-03-03 2004-11-30 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Cell usable in serum-free culture and suspension culture and process for producing virus for vaccine by using the cell DK1317559T3 (en) 2000-04-28 2009-03-23 St Jude Childrens Res Hospital DNA transfection system to produce infectious negative-stranded RNA virus FR2808803B1 (en) 2000-05-11 2004-12-10 Agronomique Inst Nat Rech MODIFIED ES CELLS AND SPECIFIC GENE OF ES CELLS AU2001293233A1 (en) 2000-09-01 2002-03-13 Chiron Corporation Aza heterocyclic derivatives and their therapeutic use JP4361727B2 (en) 2000-09-11 2009-11-11 ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド Quinolinone derivatives as tyrosine kinase inhibitors ATE384072T1 (en) 2000-09-26 2008-02-15 Idera Pharmaceuticals Inc MODULATION OF THE IMMUNOSTIMULATIVE ACTIVITY OF IMMUNOSTIMULATIVE OLIGONUCLEOTIDE ANALOGS THROUGH POSITIONAL CHEMICAL CHANGES GB0024089D0 (en) 2000-10-02 2000-11-15 Smithkline Beecham Biolog Novel compounds US6664260B2 (en) 2000-12-08 2003-12-16 3M Innovative Properties Company Heterocyclic ether substituted imidazoquinolines UA74852C2 (en) 2000-12-08 2006-02-15 3M Innovative Properties Co Urea-substituted imidazoquinoline ethers US6660747B2 (en) 2000-12-08 2003-12-09 3M Innovative Properties Company Amido ether substituted imidazoquinolines US6677348B2 (en) 2000-12-08 2004-01-13 3M Innovative Properties Company Aryl ether substituted imidazoquinolines US6667312B2 (en) 2000-12-08 2003-12-23 3M Innovative Properties Company Thioether substituted imidazoquinolines US6664264B2 (en) 2000-12-08 2003-12-16 3M Innovative Properties Company Thioether substituted imidazoquinolines US6677347B2 (en) 2000-12-08 2004-01-13 3M Innovative Properties Company Sulfonamido ether substituted imidazoquinolines US6660735B2 (en) 2000-12-08 2003-12-09 3M Innovative Properties Company Urea substituted imidazoquinoline ethers US6664265B2 (en) 2000-12-08 2003-12-16 3M Innovative Properties Company Amido ether substituted imidazoquinolines CA2438960A1 (en) 2001-02-23 2002-09-06 Glaxosmithkline Biologicals S.A. Influenza vaccine formulations for intradermal delivery US20040071734A1 (en) 2001-02-23 2004-04-15 Nathalie Garcon Novel vaccine ATE489968T1 (en) 2001-03-09 2010-12-15 Id Biomedical Corp Quebec PROTEOSOME-LIPOSACCHARIDE VACCINE ADJUVANT TWI228420B (en) 2001-05-30 2005-03-01 Smithkline Beecham Pharma Gmbh Novel vaccine composition US6592136B2 (en) 2001-07-02 2003-07-15 Fox Factory, Inc. Bicycle fork cartridge assembly WO2003035836A2 (en) 2001-10-24 2003-05-01 Hybridon Inc. Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends FR2832423B1 (en) 2001-11-22 2004-10-08 Vivalis EXOGENOUS PROTEIN EXPRESSION SYSTEM IN AN AVIAN SYSTEM MXPA04004966A (en) 2001-11-27 2006-03-21 Anadys Pharmaceuticals Inc 3-beta-D-RIBOFURANOSYLTHIAZOLO[4,5-d. US7321033B2 (en) 2001-11-27 2008-01-22 Anadys Pharmaceuticals, Inc. 3-B-D-ribofuranosylthiazolo [4,5-d] pyrimidine nucleosides and uses thereof US6677349B1 (en) 2001-12-21 2004-01-13 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines FR2836924B1 (en) 2002-03-08 2005-01-14 Vivalis AVIAN CELL LINES USEFUL FOR THE PRODUCTION OF INTEREST SUBSTANCES DK1499311T3 (en) 2002-03-29 2010-03-08 Novartis Vaccines & Diagnostic Substituted benzols and their use as RAF kinase inhibitors AU2003233519A1 (en) 2002-05-29 2003-12-19 3M Innovative Properties Company Process for imidazo(4,5-c)pyridin-4-amines JP2005533057A (en) 2002-06-13 2005-11-04 ニューヨーク・ユニバーシティ Synthetic C-glycolipids and the use of synthetic C-glycolipids to treat cancer, infectious and autoimmune diseases CA2496246A1 (en) 2002-08-23 2004-03-04 Chiron Corporation Pyrrole based inhibitors of glycogen synthase kinase 3 US7521062B2 (en) 2002-12-27 2009-04-21 Novartis Vaccines & Diagnostics, Inc. Thiosemicarbazones as anti-virals and immunopotentiators EP1594524B1 (en) 2003-01-21 2012-08-15 Novartis Vaccines and Diagnostics, Inc. Use of tryptanthrin compounds for immune potentiation GB0301554D0 (en) 2003-01-23 2003-02-26 Molecularnature Ltd Immunostimulatory compositions US7893096B2 (en) 2003-03-28 2011-02-22 Novartis Vaccines And Diagnostics, Inc. Use of small molecule compounds for immunopotentiation RU2236257C1 (en) 2003-09-15 2004-09-20 Косяков Константин Сергеевич Synthetic immunogen for therapy and prophylaxis of addiction with narcotic and psychoactive substances US7771726B2 (en) 2003-10-08 2010-08-10 New York University Use of synthetic glycolipids as universal adjuvants for vaccines against cancer and infectious diseases EP1528101A1 (en) 2003-11-03 2005-05-04 ProBioGen AG Immortalized avian cell lines for virus production US20080254065A1 (en) * 2004-03-09 2008-10-16 Chiron Corporation Influenza Virus Vaccines KR101153898B1 (en) 2004-03-23 2012-06-18 니프로 가부시키가이샤 Pre-filled syringe JP2007531768A (en) 2004-03-31 2007-11-08 ニューヨーク・ユニバーシティ Novel synthetic C-glycolipids, their synthesis and use for treating infectious diseases, cancer and autoimmune diseases SI1742659T1 (en) 2004-04-05 2013-07-31 Zoetis P Llc Microfluidized oil-in-water emulsions and vaccine compositions WO2005113756A1 (en) 2004-05-14 2005-12-01 Glaxosmithkline Biologicals S.A. Method BRPI0511152A (en) 2004-05-20 2007-12-04 Id Biomedical Corp process for producing an influenza vaccine CA2571421A1 (en) 2004-06-24 2006-01-05 Nicholas Valiante Compounds for immunopotentiation DK2236155T3 (en) 2004-09-09 2012-08-13 Novartis Vaccines & Diagnostic Reducing potential iatrogenic risks associated with influenza vaccines KR101260084B1 (en) 2004-12-23 2013-05-03 메디뮨 엘엘씨 Non-tumorigenic mdck cell line for propagating viruses KR101272487B1 (en) 2004-12-24 2013-06-07 에라스무스 유니버시티 메디컬 센터 로테르담 Rescue of influenza virus FR2884255B1 (en) 2005-04-11 2010-11-05 Vivalis USE OF EBX AVIATION STEM CELL LINES FOR THE PRODUCTION OF INFLUENZA VACCINE CA2656705A1 (en) * 2005-08-16 2007-02-22 Hawaii Biotech, Inc. Influenza recombinant subunit vaccine DK1951296T4 (en) 2005-11-01 2014-09-01 Novartis Vaccines & Diagnostic Cell-derived viral vaccines with low levels of residual cell DNA ES2385842T3 (en) * 2005-12-06 2012-08-01 Yeda Research And Development Co., Ltd. Improved flu vaccine