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NO991569L - Liquid alendronate compounds - Google Patents

  • ️Fri Jun 04 1999

NO991569L - Liquid alendronate compounds - Google Patents

Liquid alendronate compounds

Info

Publication number
NO991569L
NO991569L NO991569A NO991569A NO991569L NO 991569 L NO991569 L NO 991569L NO 991569 A NO991569 A NO 991569A NO 991569 A NO991569 A NO 991569A NO 991569 L NO991569 L NO 991569L Authority
NO
Norway
Prior art keywords
liquid
compounds
preparation
liquid alendronate
alendronate compounds
Prior art date
1996-10-04
Application number
NO991569A
Other languages
Norwegian (no)
Other versions
NO991569D0 (en
Inventor
Maneesh J Nerurkar
William H Hunke
Drazen Ostovic
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
1996-10-04
Filing date
1999-03-30
Publication date
1999-06-04
1997-01-13 Priority claimed from GBGB9700541.7A external-priority patent/GB9700541D0/en
1999-03-30 Application filed by Merck & Co Inc filed Critical Merck & Co Inc
1999-03-30 Publication of NO991569D0 publication Critical patent/NO991569D0/en
1999-06-04 Publication of NO991569L publication Critical patent/NO991569L/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Flytende preparat av alendronsyre eller et farmasøytisk akseptabelt salt som har nok buffer, slik at pH i preparatet er 4-7,5, og 15 ml av preparatet har evnen til å heve pH i 50 ml 0,1 N HC1 fra l til minst 3, og fortrinnsvis 4.Liquid preparation of alendronic acid or a pharmaceutically acceptable salt having sufficient buffer, so that the pH of the preparation is 4-7.5, and 15 ml of the preparation has the ability to raise the pH in 50 ml of 0.1 N HCl from 1 to at least 3 , and preferably 4.

NO991569A 1996-10-04 1999-03-30 Liquid alendronate compounds NO991569L (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US2676596P 1996-10-04 1996-10-04
GBGB9700541.7A GB9700541D0 (en) 1997-01-13 1997-01-13 Liquid alendronate formulation
US3600297P 1997-01-22 1997-01-22
PCT/US1997/015740 WO1998014196A1 (en) 1996-10-04 1997-10-02 Liquid alendronate formulations

Publications (2)

Publication Number Publication Date
NO991569D0 NO991569D0 (en) 1999-03-30
NO991569L true NO991569L (en) 1999-06-04

Family

ID=27268667

Family Applications (1)

Application Number Title Priority Date Filing Date
NO991569A NO991569L (en) 1996-10-04 1999-03-30 Liquid alendronate compounds

Country Status (20)

Country Link
EP (1) EP1007054A4 (en)
JP (1) JP2001501222A (en)
CN (1) CN1238691A (en)
AU (1) AU723357B2 (en)
BG (1) BG103306A (en)
BR (1) BR9712197A (en)
CA (1) CA2267370A1 (en)
CZ (1) CZ116999A3 (en)
EA (1) EA001213B1 (en)
EE (1) EE03669B1 (en)
HU (1) HUP0000125A3 (en)
IL (1) IL129127A0 (en)
IS (1) IS5012A (en)
NO (1) NO991569L (en)
NZ (1) NZ334836A (en)
PL (1) PL332496A1 (en)
SK (1) SK42999A3 (en)
TR (1) TR199900730T2 (en)
WO (1) WO1998014196A1 (en)
YU (1) YU17499A (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7560490B2 (en) * 2001-01-23 2009-07-14 Gador S.A. Composition comprising bisphosphonates for prevention and/or treatment of metabolic diseases of bones, process for preparing such composition and use thereof
US7645460B2 (en) 2004-05-24 2010-01-12 The Procter & Gamble Company Dosage forms of risedronate
US7645459B2 (en) 2004-05-24 2010-01-12 The Procter & Gamble Company Dosage forms of bisphosphonates
US20080286359A1 (en) 2004-05-24 2008-11-20 Richard John Dansereau Low Dosage Forms Of Risedronate Or Its Salts
US20080287400A1 (en) 2004-05-24 2008-11-20 Richard John Dansereau Low Dosage Forms Of Risedronate Or Its Salts
JP2009508834A (en) * 2005-09-16 2009-03-05 セラマイン リミテッド Bisphosphonate formulation
US7473684B2 (en) 2005-09-16 2009-01-06 Selamine Limited Bisphosphonate formulation
JP2010043119A (en) * 2009-10-16 2010-02-25 Gador Sa Composition for preventing and/or treating bone metabolic disease, method of preparing the same and use thereof
US8568747B1 (en) 2012-10-05 2013-10-29 Silvergate Pharmaceuticals, Inc. Enalapril compositions
US9463183B1 (en) 2015-10-30 2016-10-11 Silvergate Pharmaceuticals, Inc. Lisinopril formulations
US9669008B1 (en) 2016-03-18 2017-06-06 Silvergate Pharmaceuticals, Inc. Enalapril formulations

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206209A (en) * 1978-11-02 1980-06-03 Kracauer Paul Sublingual aspirin tablet
IT1201087B (en) * 1982-04-15 1989-01-27 Gentili Ist Spa PHARMACOLOGICALLY ACTIVE BIPPHOSPHONES, PROCEDURE FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS
US4922007A (en) * 1989-06-09 1990-05-01 Merck & Co., Inc. Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof
US5019651A (en) * 1990-06-20 1991-05-28 Merck & Co., Inc. Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP) or salts thereof
US5270365A (en) * 1991-12-17 1993-12-14 Merck & Co., Inc. Prevention and treatment of periodontal disease with alendronate
US5358941A (en) * 1992-12-02 1994-10-25 Merck & Co., Inc. Dry mix formulation for bisphosphonic acids with lactose
FR2703590B1 (en) * 1993-04-05 1995-06-30 Sanofi Elf USE OF BISPHOSPHONIC ACID DERIVATIVES FOR THE PREPARATION OF MEDICINES FOR PROMOTING BONE REPAIR.
US5510517A (en) * 1993-08-25 1996-04-23 Merck & Co., Inc. Process for producing N-amino-1-hydroxy-alkylidene-1,1-bisphosphonic acids
US5462932A (en) * 1994-05-17 1995-10-31 Merck & Co., Inc. Oral liquid alendronate formulations
US5780455A (en) * 1994-08-24 1998-07-14 Merck & Co., Inc. Intravenous alendronate formulations
US5616571A (en) * 1995-06-06 1997-04-01 Merck & Co., Inc. Bisphosphonates prevent bone loss associated with immunosuppressive therapy

Also Published As

Publication number Publication date
PL332496A1 (en) 1999-09-13
CA2267370A1 (en) 1998-04-09
IL129127A0 (en) 2000-02-17
AU4644897A (en) 1998-04-24
AU723357B2 (en) 2000-08-24
SK42999A3 (en) 2000-01-18
HUP0000125A3 (en) 2001-04-28
CZ116999A3 (en) 1999-09-15
TR199900730T2 (en) 1999-07-21
EP1007054A4 (en) 2000-07-19
YU17499A (en) 1999-11-22
EA001213B1 (en) 2000-12-25
EE9900113A (en) 1999-10-15
BG103306A (en) 2000-01-31
EA199900352A1 (en) 1999-08-26
CN1238691A (en) 1999-12-15
EP1007054A1 (en) 2000-06-14
WO1998014196A1 (en) 1998-04-09
IS5012A (en) 1999-03-26
BR9712197A (en) 1999-08-31
EE03669B1 (en) 2002-04-15
JP2001501222A (en) 2001-01-30
NZ334836A (en) 2000-11-24
NO991569D0 (en) 1999-03-30
HUP0000125A2 (en) 2000-06-28

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Legal Events

Date Code Title Description
2003-03-03 FC2A Withdrawal, rejection or dismissal of laid open patent application