SG11201703553TA - Compositions comprising cyclosporin - Google Patents

US3536809A (en) 1969-02-17 1970-10-27 Alza Corp Medication method US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway US3971852A (en) 1973-06-12 1976-07-27 Polak's Frutal Works, Inc. Process of encapsulating an oil and product produced thereby US4008719A (en) 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent IT1090703B (en) 1976-12-03 1985-06-26 Scherer Ltd R P IMPROVEMENT IN USEFUL COMPOSITIONS SUCH AS DRUG VEHICLES US4123403A (en) 1977-06-27 1978-10-31 The Dow Chemical Company Continuous process for preparing aqueous polymer microsuspensions SE445174B (en) 1978-03-07 1986-06-09 Sandoz Ag PHARMACEUTICAL COMPOSITION CONTAINING A CYCLOSPORIN AND A HEALING SUBSTANCE US4279632A (en) 1979-05-08 1981-07-21 Nasa Method and apparatus for producing concentric hollow spheres IT1148784B (en) 1980-04-09 1986-12-03 Eurand Spa PROCEDURE FOR THE PREPARATION OF MICRO CAPSULES IN A LIQUID VEHICLE US4379454A (en) 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer JPS5877810A (en) 1981-11-01 1983-05-11 Taiho Yakuhin Kogyo Kk Oral drug composition containing polyglycerol unsaturated fatty acid ester DE3224619A1 (en) 1981-07-14 1983-05-19 Freund Industrial Co., Ltd., Tokyo Oral pharmaceutical composition JPS5813508A (en) 1981-07-14 1983-01-26 Taiho Yakuhin Kogyo Kk Drug containing polyglycerol ester of fatty acid US4481157A (en) 1982-04-27 1984-11-06 Morishita Jintan Co., Ltd. Method and apparatus for production of microcapsules US4597959A (en) 1982-04-30 1986-07-01 Arthur Barr Sustained release breath freshener, mouth and palate coolant wafer composition and method of use US4422985A (en) 1982-09-24 1983-12-27 Morishita Jintan Co., Ltd. Method and apparatus for encapsulation of a liquid or meltable solid material JPS5988420A (en) 1982-11-12 1984-05-22 Teisan Seiyaku Kk Seamless encapsulated nifedipine pharmaceutical US4502888A (en) 1982-12-13 1985-03-05 The Dow Chemical Company Aqueous dispersions of plasticized polymer particles JPS59131355A (en) 1983-01-17 1984-07-28 森下仁丹株式会社 Multiple soft capsule HU187215B (en) 1983-01-26 1985-11-28 Egyt Gyogyszervegyeszeti Gyar Method for producing pharmaceutical product of high actor content and prolonged effect DE3331009A1 (en) 1983-08-27 1985-03-14 Basf Ag, 6700 Ludwigshafen METHOD FOR INCREASING THE ENTERAL RESORBABILITY OF HEPARIN OR. HEPARINOIDS AND THE SO AVAILABLE HEPARIN OR HEPARINOID PREPARATION JPS60100516A (en) 1983-11-04 1985-06-04 Takeda Chem Ind Ltd Preparation of sustained release microcapsule US4659700A (en) 1984-03-02 1987-04-21 Johnson & Johnson Products, Inc. Chitosan-glycerol-water gel US5639724A (en) * 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation JPS61126016A (en) 1984-11-22 1986-06-13 Toagosei Chem Ind Co Ltd Microcapsule containing unsaturated fatty acid JPS61151119A (en) 1984-12-24 1986-07-09 Taisho Pharmaceut Co Ltd Seamless capsule US4601894A (en) 1985-03-29 1986-07-22 Schering Corporation Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate US4749574A (en) 1986-04-14 1988-06-07 Fujisawa Pharmaceutical Co., Ltd. Sustained-release transdermal delivery preparations US4857335A (en) 1987-03-27 1989-08-15 Lim Technology Laboratories, Inc. Liquid controlled release formulations and method of producing same via multiple emulsion process US4891223A (en) 1987-09-03 1990-01-02 Air Products And Chemicals, Inc. Controlled release delivery coating formulation for bioactive substances ATE109970T1 (en) 1987-09-03 1994-09-15 Univ Georgia Res Found CYCLOSPORIN EYE REMEDY. JPS6415A (en) 1988-03-17 1989-01-05 Freunt Ind Co Ltd Absorption-improving drug preparation US4910191A (en) 1988-06-28 1990-03-20 Merrell Dow Pharmaceuticals Inc. 19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors US5073543A (en) 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle US5350741A (en) 1988-07-30 1994-09-27 Kanji Takada Enteric formulations of physiologically active peptides and proteins US5342625A (en) 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins KR0148748B1 (en) 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 Pharmaceutical composition containing cyclosporin PH26730A (en) 1988-12-30 1992-09-28 Ciba Geigy Ag Coated adhesive tablets IT1229203B (en) 1989-03-22 1991-07-25 Bioresearch Spa USE OF 5 METHYLTHETRAHYDROPHOLIC ACID, 5 FORMYLTHETRAHYDROPHOLIC ACID AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS IN THE FORM OF CONTROLLED RELEASE ACTIVE IN THE THERAPY OF MENTAL AND ORGANIC DISORDERS. US5133974A (en) 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations JP2806564B2 (en) 1989-07-20 1998-09-30 森下仁丹株式会社 SEAMLESS CAPSULES CONTAINING A HYDROPHILIC SUBSTANCE AND METHOD OF PRODUCING THE SAME US5120548A (en) 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device GB8926639D0 (en) 1989-11-24 1990-01-17 Agricultural & Food Res Delayed release formulations US5260071A (en) 1989-12-18 1993-11-09 Lemelson Jerome H Drug units and methods for using same US5733566A (en) 1990-05-15 1998-03-31 Alkermes Controlled Therapeutics Inc. Ii Controlled release of antiparasitic agents in animals DK0465238T3 (en) 1990-07-04 1994-05-02 Shionogi & Co Process for the preparation of non-cohesive coatings US5102668A (en) 1990-10-05 1992-04-07 Kingaform Technology, Inc. Sustained release pharmaceutical preparation using diffusion barriers whose permeabilities change in response to changing pH US5418010A (en) 1990-10-05 1995-05-23 Griffith Laboratories Worldwide, Inc. Microencapsulation process US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles GB9113872D0 (en) 1991-06-27 1991-08-14 Sandoz Ag Improvements in or relating to organic compounds AU661021B2 (en) 1991-06-28 1995-07-13 Brown University Research Foundation Capsule extrusion systems JP3313124B2 (en) 1991-07-31 2002-08-12 森下仁丹株式会社 SEAMLESS CAPSULES CONTAINING A HYDROPHILIC SUBSTANCE AND PROCESS FOR PRODUCING THE SAME JPH0549899A (en) 1991-08-09 1993-03-02 Japan Tobacco Inc Bead and liquid drop forming device for producing this bead US5580578A (en) 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers AU666895B2 (en) 1991-12-30 1996-02-29 Hercules Incorporated High load spray dry encapsulation DE4201179A1 (en) 1992-01-17 1993-07-22 Alfatec Pharma Gmbh Granulates or pellets comprising dispersion of active agent in hydrophilic macromolecules - are e.g. for treatment of depression, hypertension, rheumatism, etc. DE59307073D1 (en) 1992-01-17 1997-09-11 Alfatec Pharma Gmbh PELLETS CONTAINING PEPTIC DRUGS AND THEIR PRODUCTION AND USE THEREOF US5571533A (en) 1992-02-07 1996-11-05 Recordati, S.A., Chemical And Pharmaceutical Company Controlled-release mucoadhesive pharmaceutical composition for the oral administration of furosemide EP0573978B1 (en) 1992-06-12 1999-04-21 Kao Corporation Bath additive composition comprising surfactant-containing seamless capsules and method for producing the capsules. ES2179829T3 (en) 1992-09-18 2003-02-01 Yamanouchi Pharma Co Ltd PREPARATION OF HYDROGEL OF PROLONGED RELEASE. JP3405746B2 (en) 1992-10-28 2003-05-12 フロイント産業株式会社 Manufacturing method of seamless capsule KR100291357B1 (en) 1993-01-08 2001-09-17 터베이 피터. Vaccine formulation GB9300875D0 (en) 1993-01-18 1993-03-10 Ucb Sa Nanocapsule containing pharmaceutical compositions US5591767A (en) 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac US5914132A (en) 1993-02-26 1999-06-22 The Procter & Gamble Company Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery US5686105A (en) 1993-10-19 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery JPH06254382A (en) 1993-03-05 1994-09-13 Riken Vitamin Co Ltd Production of microcapsule and its apparatus for production US5843347A (en) 1993-03-23 1998-12-01 Laboratoire L. Lafon Extrusion and freeze-drying method for preparing particles containing an active ingredient CN1077800C (en) 1993-07-01 2002-01-16 韩美药品工业株式会社 Cyclosporin soft capsule composition DE4322826A1 (en) * 1993-07-08 1995-01-12 Galenik Labor Freiburg Gmbh Pharmaceutical preparation FR2707184B1 (en) 1993-07-08 1995-08-11 Rhone Poulenc Nutrition Animal Process for the preparation of spherules containing an active food or pharmaceutical ingredient. US5562909A (en) 1993-07-12 1996-10-08 Massachusetts Institute Of Technology Phosphazene polyelectrolytes as immunoadjuvants DE4329503A1 (en) 1993-09-01 1995-03-02 Galenik Labor Freiburg Gmbh Pharmaceutical preparations for the targeted treatment of Crohn's disease and ulcerative colitis DE4332041C2 (en) 1993-09-21 1997-12-11 Rentschler Arzneimittel Use of pentoxifylline in certain lung diseases US5961970A (en) 1993-10-29 1999-10-05 Pharmos Corporation Submicron emulsions as vaccine adjuvants EP0694308A4 (en) * 1994-02-17 1997-09-10 Shiseido Co Ltd Cyclosporin-containing emulsion composition US5498439A (en) 1994-03-04 1996-03-12 Arnhem, Inc. Process for encapsulating the flavor with colloid gel matrix GB9405304D0 (en) 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs FR2721510B1 (en) 1994-06-22 1996-07-26 Rhone Poulenc Rorer Sa Nanoparticles filterable under sterile conditions. IT1270594B (en) 1994-07-07 1997-05-07 Recordati Chem Pharm CONTROLLED RELEASE PHARMACEUTICAL COMPOSITION OF LIQUID SUSPENSION MOGUISTEIN US5650232A (en) 1994-10-07 1997-07-22 Warner-Lambert Company Method for making seamless capsules FR2725623A1 (en) 1994-10-18 1996-04-19 Flamel Tech Sa MEDICINAL AND / OR NUTRITION MICROCAPSULES FOR PER OS ADMINISTRATION US5827531A (en) 1994-12-02 1998-10-27 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Microcapsules and methods for making US5529783A (en) 1994-12-19 1996-06-25 Mcneil-Ppc, Inc. Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan KR0167613B1 (en) 1994-12-28 1999-01-15 한스 루돌프 하우스, 니콜 케르커 Cyclosporine-containing soft capsule composition US5510118A (en) 1995-02-14 1996-04-23 Nanosystems Llc Process for preparing therapeutic compositions containing nanoparticles US5674495A (en) 1995-02-27 1997-10-07 Purdue Research Foundation Alginate-based vaccine compositions US5595757A (en) 1995-03-29 1997-01-21 Warner-Lambert Company Seamless capsules US5665386A (en) 1995-06-07 1997-09-09 Avmax, Inc. Use of essential oils to increase bioavailability of oral pharmaceutical compounds IE80467B1 (en) 1995-07-03 1998-07-29 Elan Corp Plc Controlled release formulations for poorly soluble drugs SE504582C2 (en) * 1995-07-06 1997-03-10 Gs Dev Ab Cyclosporin composition based on an L2 phase DE789561T1 (en) 1995-08-25 1999-06-10 Sangstat Medical Corp., Menlo Park, Calif. ORAL CYCLOSPORINE FORMULATIONS EP0760237A1 (en) 1995-08-30 1997-03-05 Cipla Limited Oil-in-water microemulsions DE19549852B4 (en) 1995-11-29 2009-06-04 Novartis Ag Cyclosporin containing preparations JP3759986B2 (en) 1995-12-07 2006-03-29 フロイント産業株式会社 Seamless capsule and manufacturing method thereof US5858401A (en) 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines US5686133A (en) 1996-01-31 1997-11-11 Port Systems, L.L.C. Water soluble pharmaceutical coating and method for producing coated pharmaceuticals KR0183449B1 (en) 1996-06-19 1999-05-01 한스 루돌프 하우스, 니콜 케르커 Cyclosporine-containing soft capsules US5958876A (en) 1996-06-19 1999-09-28 Novartis Ag Cyclosporin-containing pharmaceutical compositions WO1998018610A1 (en) 1996-10-28 1998-05-07 Lengerich Bernhard H Van Embedding and encapsulation of controlled release particles CN1242702A (en) * 1996-12-31 2000-01-26 扇形支撑剑桥有限公司 Method and compositions for improved bioavailability of bioactive agent for mucosal delivery US5891474A (en) 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same WO1998040051A1 (en) * 1997-03-12 1998-09-17 Abbott Laboratories Lipophilic binary systems for the administration of lipophilic compounds DZ2479A1 (en) 1997-05-05 2003-02-01 Pfizer Anti-inflammatory selective co-2 inhibitor compounds and pharmaceutical compositions containing them. WO1998050018A1 (en) 1997-05-06 1998-11-12 Xiao Yu Wu Drug delivery system JP4102459B2 (en) 1997-05-14 2008-06-18 森下仁丹株式会社 Seamless capsule for synthesizing biopolymer and method for producing the same SE9702533D0 (en) 1997-07-01 1997-07-01 Astra Ab New oral formulation RU2211021C2 (en) 1997-07-29 2003-08-27 Фармация Энд Апджон Компани Pharmaceutical self-emulsifying composition and its carrier for lipophilic pharmaceutically active agents ES2137862B1 (en) 1997-07-31 2000-09-16 Intexim S A ORAL PHARMACEUTICAL PREPARATION INCLUDING A COMPOUND OF ANTI-ULCER ACTIVITY AND PROCEDURE FOR ITS OBTAINING. JP3090198B2 (en) 1997-08-21 2000-09-18 日本電気株式会社 Structure of semiconductor device and method of manufacturing the same HUP9701554D0 (en) 1997-09-18 1997-11-28 Human Oltoanyagtermeloe Gyogys Pharmaceutical composition containing plazma proteins WO1999022719A1 (en) 1997-10-30 1999-05-14 Morishita Jintan Co., Ltd. Capsular preparation containing unsaturated fatty acid or derivative thereof and process for producing the same IT1296585B1 (en) 1997-11-28 1999-07-14 Uni Di Pavia MICROCAPS CONTAINING SEMINAL MATERIAL FOR INSTRUMENTAL INSEMINATION IN THE SWINE SPECIES US6509346B2 (en) 1998-01-21 2003-01-21 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor US20040062802A1 (en) 1998-04-02 2004-04-01 Hermelin Victor M. Maximizing effectiveness of substances used to improve health and well being US6174466B1 (en) 1998-05-08 2001-01-16 Warner-Lambert Company Methods for making seamless capsules JPH11322587A (en) 1998-05-18 1999-11-24 Sumitomo Chem Co Ltd Method for microencapsulating a physiologically active substance solid at room temperature and microcapsule composition obtained by this method KR100336090B1 (en) 1998-06-27 2002-05-27 윤승원 Solid dispersed preparation of poorly water-soluble drug containing oil, fatty acid or mixture thereof DE19848849A1 (en) 1998-10-22 2000-04-27 Knoll Ag Free-flowing, homogeneous spheres of active agent, e.g. drug, in auxiliary matrix, obtained by dropping molten mixture from nozzle into fluid for freezing and solidification AU775523B2 (en) 1998-12-11 2004-08-05 Pharmasolutions, Inc. Self-emulsifying compositions for drugs poorly soluble in water US6294192B1 (en) 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents JP2000247911A (en) 1999-02-26 2000-09-12 Hisamitsu Pharmaceut Co Inc Absorption promoter for large intestine US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions US7374779B2 (en) 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents US6761903B2 (en) 1999-06-30 2004-07-13 Lipocine, Inc. Clear oil-containing pharmaceutical compositions containing a therapeutic agent US20030104048A1 (en) 1999-02-26 2003-06-05 Lipocine, Inc. Pharmaceutical dosage forms for highly hydrophilic materials US6267985B1 (en) 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions JP2000302654A (en) 1999-04-16 2000-10-31 Kao Corp Production of dentifrice composition US8663692B1 (en) 1999-05-07 2014-03-04 Pharmasol Gmbh Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same WO2000069420A1 (en) 1999-05-14 2000-11-23 Coraltis Ltd. Pulse-delivery oral compositions EP1184038B1 (en) 1999-06-09 2005-12-28 Mochida Pharmaceutical Co., Ltd. System for release in lower digestive tract US20030235595A1 (en) 1999-06-30 2003-12-25 Feng-Jing Chen Oil-containing, orally administrable pharmaceutical composition for improved delivery of a therapeutic agent US6458383B2 (en) 1999-08-17 2002-10-01 Lipocine, Inc. Pharmaceutical dosage form for oral administration of hydrophilic drugs, particularly low molecular weight heparin US20030236236A1 (en) 1999-06-30 2003-12-25 Feng-Jing Chen Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs US6309663B1 (en) 1999-08-17 2001-10-30 Lipocine Inc. Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents KR100710118B1 (en) 1999-07-30 2007-04-23 스미스클라인비이참피이엘시이 Multi-Component Pharmaceutical Formulations WO2001032142A1 (en) 1999-11-02 2001-05-10 Cipla Limited Cyclosporin formulation US20030180352A1 (en) 1999-11-23 2003-09-25 Patel Mahesh V. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions US20060034937A1 (en) 1999-11-23 2006-02-16 Mahesh Patel Solid carriers for improved delivery of active ingredients in pharmaceutical compositions EP1244468A2 (en) 2000-01-07 2002-10-02 University Of Cincinnati Selective activation of a th1 or th2 lymphocyte regulated immune response DK1280521T3 (en) 2000-05-12 2005-08-08 Pharmacia & Upjohn Co Llc Vaccine composition, method of preparation thereof and method of vaccination of vertebrates US20040258702A1 (en) 2000-06-22 2004-12-23 Blonder Joan P. Vaccine delivery GB0018527D0 (en) 2000-07-27 2000-09-13 Photocure Asa Composition US6565888B1 (en) 2000-08-23 2003-05-20 Alkermes Controlled Therapeutics, Inc. Methods and compositions for the targeted delivery of biologically active agents FI20002215A0 (en) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Combination Particles US7115565B2 (en) * 2001-01-18 2006-10-03 Pharmacia & Upjohn Company Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability CA2437899C (en) 2001-02-13 2012-05-15 Gregory M. Glenn Vaccine for transcutaneous immunization against etec-caused traveler's diarrhea CN1543345A (en) 2001-05-09 2004-11-03 诺瓦提斯公司 Methods for selective immunomodulation using pimecrolimus ITMI20011337A1 (en) 2001-06-26 2002-12-26 Farmatron Ltd ORAL PHARMACEUTICAL COMPOSITIONS WITH MODIFIED RELEASE OF THE ACTIVE SUBSTANCE EP1434859A2 (en) 2001-07-25 2004-07-07 New York University Use of glycosylceramides as adjuvants for vaccines against infections and cancer US6585997B2 (en) 2001-08-16 2003-07-01 Access Pharmaceuticals, Inc. Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds US20030083286A1 (en) 2001-08-22 2003-05-01 Ching-Leou Teng Bioadhesive compositions and methods for enhanced intestinal drug absorption US6669955B2 (en) 2001-08-28 2003-12-30 Longwood Pharmaceutical Research, Inc. Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin FR2830447B1 (en) 2001-10-09 2004-04-16 Flamel Tech Sa MICROPARTICULAR ORAL GALENIC FORM FOR DELAYED AND CONTROLLED RELEASE OF PHARMACEUTICAL ACTIVE INGREDIENTS US6951655B2 (en) 2001-10-11 2005-10-04 Imi Biomed, Inc. Pro-micelle pharmaceutical compositions US20040126428A1 (en) 2001-11-02 2004-07-01 Lyn Hughes Pharmaceutical formulation including a resinate and an aversive agent EP1455753A1 (en) 2001-12-20 2004-09-15 Bernard Charles Sherman Pharmaceutical compositions comprising a cyclosporin, a hydrophilic surfactant and a lipophilic surfactant ATE333802T1 (en) 2002-01-10 2006-08-15 Firmenich & Cie PROCESS FOR PRODUCING EXTRUDED DELIVERY SYSTEMS US6949256B2 (en) 2002-01-18 2005-09-27 Banner Pharmacaps, Inc. Non-gelatin capsule shell formulation US6974592B2 (en) 2002-04-11 2005-12-13 Ocean Nutrition Canada Limited Encapsulated agglomeration of microcapsules and method for the preparation thereof US20030207907A1 (en) 2002-05-03 2003-11-06 Iversen Patrick L. Delivery of microparticle-conjugated drugs for inhibition of stenosis JP4226846B2 (en) 2002-06-07 2009-02-18 キャタレント・ジャパン株式会社 Soft capsule that can disintegrate in the oral cavity GB2391473B (en) * 2002-08-02 2004-07-07 Satishchandra Punambhai Patel Pharmaceutical compositions KR100487409B1 (en) 2002-08-08 2005-05-03 주식회사 유에스디 Method for recording telephone voice in multi-channel digital recording system WO2004022220A1 (en) 2002-09-04 2004-03-18 Southwest Research Institute Microencapsulation of oxygen or water sensitive materials WO2004042024A2 (en) 2002-11-01 2004-05-21 The Trustees Of The University Of Pennsylvania COMPOSITIONS AND METHODS FOR siRNA INHIBITION OF HIF-1 ALPHA US7524515B2 (en) 2003-01-10 2009-04-28 Mutual Pharmaceuticals, Inc. Pharmaceutical safety dosage forms WO2004064997A1 (en) 2003-01-23 2004-08-05 Inotech Ag New microcapsules useful as extraction means in particular for extracting water or soil contaminants EP1608347B1 (en) 2003-03-28 2014-08-13 Sigmoid Pharma Limited Solid oral dosage form containing seamless microcapsules RU2541809C2 (en) 2003-04-04 2015-02-20 Зоетис Пи ЛЛК Mucrofluidic oil-in-water emulsion and vaccine compositions US8614204B2 (en) 2003-06-06 2013-12-24 Fibrogen, Inc. Enhanced erythropoiesis and iron metabolism DE602004028023D1 (en) 2003-08-29 2010-08-19 Lifecycle Pharma As TACROLIMUS CONTAINING SOLID DISPERSIONS US7087237B2 (en) 2003-09-19 2006-08-08 Advanced Ocular Systems Limited Ocular solutions US20050095288A1 (en) 2003-11-03 2005-05-05 Andrx Labs, Llc Decongestant and expectorant tablets US9592201B2 (en) 2003-11-21 2017-03-14 Commonwealth Scientific And Industrial Research Organisation Gi track delivery systems EP1697511A4 (en) 2003-12-11 2007-11-21 Vaxdesign Corp Immunotherapy compositions, method of making and method of use thereof KR20070032272A (en) * 2003-12-16 2007-03-21 포믹스 리미티드 Oil-based pharmaceutical and cosmetic foams CN1268325C (en) 2004-01-18 2006-08-09 浙江大学 Ternary composite microsphere formulation and its preparation method JP2007519756A (en) 2004-01-30 2007-07-19 アンジオテック インターナショナル アーゲー Compositions and methods for treating contracture TW200539903A (en) 2004-03-12 2005-12-16 Smithkline Beecham Plc Pharmaceutical formulations FR2867395B1 (en) 2004-03-15 2006-06-16 Rhodia Chimie Sa DRY EMULSION, PROCESS FOR PREPARING THE SAME, AND USES THEREOF CN1938006B (en) 2004-03-31 2010-11-10 Bpsi控股公司 Enteric coatings for orally ingestible substrates PL1746980T3 (en) 2004-05-07 2012-03-30 Nycomed Gmbh Pharmaceutical dosage form comprising pellets as well as its manufacturing process GB0413730D0 (en) 2004-06-18 2004-07-21 Tillotts Pharma Ag A pharmaceutical composition and its use US7002214B1 (en) 2004-07-30 2006-02-21 International Business Machines Corporation Ultra-thin body super-steep retrograde well (SSRW) FET devices GB0417481D0 (en) 2004-08-05 2004-09-08 Etiologics Ltd Combination therapy CN100486567C (en) 2004-08-12 2009-05-13 山东绿叶天然药物研究开发有限公司 Curcumin emulsion and its preparation process ES2587016T5 (en) 2004-08-19 2020-02-27 Dsm Ip Assets Bv New compositions of fat-soluble substances WO2006026592A2 (en) 2004-08-27 2006-03-09 Spherics, Inc. Oral administration of poorly absorbed drugs, methods and compositions related thereto EP1789090A2 (en) 2004-09-02 2007-05-30 Bionaut Pharmaceuticals, Inc. Combinatorial chemotherapy treatment using na+/k+-atpase inhibitors GB0419846D0 (en) 2004-09-07 2004-10-13 Chiron Srl Vaccine adjuvants for saccharides EP1811979B1 (en) * 2004-09-27 2008-11-05 Sigmoid Pharma Limited Microcapsules comprising a methylxanthine and a corticosteroid EP1885342B8 (en) * 2005-03-21 2016-06-22 Teva Czech Industries s.r.o. Crystallization inhibitor and its use in gelatin capsules KR20080007580A (en) 2005-04-12 2008-01-22 엘란 파마 인터내셔널 리미티드 Nanoparticulate Controlled Release Composition Containing Cyclosporin KR100764678B1 (en) 2005-07-13 2007-10-09 재단법인서울대학교산학협력재단 Intranasal vaccine composition comprising alpha-galactosyl ceramide as an adjuvant US20080199516A1 (en) 2005-07-26 2008-08-21 Glaxo Group Limited Encapsulation Of Lipid-Based Formulations In Enteric Polymers WO2007014445A1 (en) 2005-08-02 2007-02-08 Miv Therapeutics Inc. Microdevices comprising nanocapsules for controlled delivery of drugs and method of manufacturing same US7842312B2 (en) 2005-12-29 2010-11-30 Cordis Corporation Polymeric compositions comprising therapeutic agents in crystalline phases, and methods of forming the same CA2638914C (en) 2006-02-09 2014-04-08 Alba Therapeutics Corporation Formulations for a tight junction effector US8039010B2 (en) 2006-11-03 2011-10-18 Allergan, Inc. Sustained release intraocular drug delivery systems comprising a water soluble therapeutic agent and a release modifier US20080124279A1 (en) 2006-11-17 2008-05-29 Antoine Andremont Colonic delivery using Zn/pectin beads with a Eudragit coating EP2061440A2 (en) 2007-04-04 2009-05-27 Sigmoid Pharma Limited A pharmaceutical composition of tacrolimus NZ600958A (en) 2007-04-06 2015-05-29 Takeda Vaccines Inc Methods and compositions for live attentuated viruses EP2061587A1 (en) 2007-04-26 2009-05-27 Sigmoid Pharma Limited Manufacture of multiple minicapsules EP2063875A2 (en) 2007-05-01 2009-06-03 Sigmoid Pharma Limited Combination pharmaceutical compositions US9833510B2 (en) 2007-06-12 2017-12-05 Johnson & Johnson Consumer Inc. Modified release solid or semi-solid dosage forms GB0712389D0 (en) * 2007-06-26 2007-08-01 Drug Delivery Solutions Ltd A Pharmaceutical composition WO2009002533A1 (en) 2007-06-27 2008-12-31 The Brigham And Women's Hospital, Inc. Inflammatory bowel disease therapies EP2483287B1 (en) 2007-10-12 2016-03-16 Luigi Panza Analogues of glycolipids useful as immunoadjuvants EP2105129B1 (en) 2008-03-24 2018-01-17 Intervet International B.V. Encapsulated Vaccines for the Oral Vaccination and Boostering of Fish and Other Animals CA2729948C (en) 2008-07-08 2021-11-23 Lifecycle Pharma A/S Tacrolimus for improved treatment of transplant patients IE20090793A1 (en) 2008-10-13 2010-06-23 Sigmoid Pharma Ltd A delivery system JP5640079B2 (en) * 2009-05-18 2014-12-10 シグモイド・ファーマ・リミテッドＳｉｇｍｏｉｄ Ｐｈａｒｍａ Ｌｉｍｉｔｅｄ Oil droplet-containing composition GEP201706606B (en) * 2010-09-03 2017-01-25 Santen Sas Water-in-oil type emulsion for treating a disease of the eye GB201020032D0 (en) * 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition DE102011051653A1 (en) 2011-07-07 2013-01-10 Lts Lohmann Therapie-Systeme Ag Swellable coated tablet GB201319791D0 (en) * 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations GB201319792D0 (en) * 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations EP2878311A1 (en) 2013-11-27 2015-06-03 Freund Pharmatec Ltd. Solubility Enhancement for Hydrophobic Drugs GB201400442D0 (en) * 2014-01-10 2014-02-26 Sigmoid Pharma Ltd Compositions for use in the treatment of ulcerative colitis EP3215127B1 (en) * 2014-11-07 2020-10-28 Sublimity Therapeutics Limited Compositions comprising cyclosporin