Mechanisms of angiogenesis and arteriogenesis - PubMed

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• PMID: 10742145
• DOI: 10.1038/74651

Review

Mechanisms of angiogenesis and arteriogenesis

P Carmeliet. Nat Med. 2000 Apr.

Abstract

Endothelial and smooth muscle cells interact with each other to form new blood vessels. In this review, the cellular and molecular mechanisms underlying the formation of endothelium-lined channels (angiogenesis) and their maturation via recruitment of smooth muscle cells (arteriogenesis) during physiological and pathological conditions are summarized, alongside with possible therapeutic applications.

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