Homer: a link between neural activity and glutamate receptor function - PubMed

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Homer: a link between neural activity and glutamate receptor function

B Xiao et al. Curr Opin Neurobiol. 2000 Jun.

Free article

Abstract

The proteins of the Homer family bind to proline-rich sequences in group I metabotropic glutamate receptors, inositol trisphosphate receptors, ryanodine receptors, and Shank family proteins. Homer proteins also self associate and function as adaptors to couple interacting proteins. Recent observations indicate a role for Homer complexes in signal transduction, synaptogenesis and receptor trafficking.

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