Short bowel syndrome - PubMed

Affiliations

• PMID: 11193712
• DOI: 10.1007/s002680010266

Review

Short bowel syndrome

D W Wilmore et al. World J Surg. 2000 Dec.

Abstract

The short bowel syndrome is a symptom complex that occurs in adults who have less than 200 cm of jejunum-ileum remaining after intestinal resection. Similar symptoms are observed in infants and children following massive bowel resection or congenital anomalies and in individuals with longer segments of intestine with severe mucosal disease. Initial care should focus on a thorough excision of nonviable bowel, an exact measurement of the remaining viable bowel, placing all intestine in continuity at the initial or subsequent operation, and controlling initial food intake. With time, adaptation of the remnant intestine occurs, and absorptive function may be maximized by enhancing the enteral diet and minimizing parenteral nutrition. Growth factors and specialized nutrients may also enhance this process. Intestinal transplantation should be considered in selected individuals with the short bowel syndrome who fail intestinal rehabilitation protocols.

Similar articles

• Current management of the short bowel syndrome.

  Thompson JS, Weseman R, Rochling FA, Mercer DF. Thompson JS, et al. Surg Clin North Am. 2011 Jun;91(3):493-510. doi: 10.1016/j.suc.2011.02.006. Surg Clin North Am. 2011. PMID: 21621693 Review.

• Short bowel syndrome in children and adults: from rehabilitation to transplantation.

  Lauro A, Lacaille F. Lauro A, et al. Expert Rev Gastroenterol Hepatol. 2019 Jan;13(1):55-70. doi: 10.1080/17474124.2019.1541736. Epub 2018 Oct 31. Expert Rev Gastroenterol Hepatol. 2019. PMID: 30791840 Review.

• Enteral nutrition regimen for neonates with short bowel syndrome.

  Theyskens C, Dams A. Theyskens C, et al. Nutrition. 2008 Oct;24(10):1045-7. doi: 10.1016/j.nut.2008.04.010. Epub 2008 Jun 30. Nutrition. 2008. PMID: 18586463

• Minimal Enteral Nutrition to Improve Adaptation After Intestinal Resection in Piglets and Infants.

  Aunsholt L, Qvist N, Sangild PT, Vegge A, Stoll B, Burrin DG, Jeppesen PB, Eriksen T, Husby S, Thymann T. Aunsholt L, et al. JPEN J Parenter Enteral Nutr. 2018 Feb;42(2):446-454. doi: 10.1177/0148607117690527. Epub 2017 Dec 20. JPEN J Parenter Enteral Nutr. 2018. PMID: 28786308

• Glucagon-like peptide-2 induces a specific pattern of adaptation in remnant jejunum.

  Sigalet DL, Bawazir O, Martin GR, Wallace LE, Zaharko G, Miller A, Zubaidi A. Sigalet DL, et al. Dig Dis Sci. 2006 Sep;51(9):1557-66. doi: 10.1007/s10620-006-9077-5. Epub 2006 Aug 22. Dig Dis Sci. 2006. PMID: 16927140

Cited by

• Liver disease secondary to intestinal failure.

  Abu-Wasel B, Molinari M. Abu-Wasel B, et al. Biomed Res Int. 2014;2014:968357. doi: 10.1155/2014/968357. Epub 2014 Jan 15. Biomed Res Int. 2014. PMID: 24551858 Free PMC article. Review.

• Development of Chitosan Scaffolds with Enhanced Mechanical Properties for Intestinal Tissue Engineering Applications.

  Zakhem E, Bitar KN. Zakhem E, et al. J Funct Biomater. 2015 Oct 13;6(4):999-1011. doi: 10.3390/jfb6040999. J Funct Biomater. 2015. PMID: 26473937 Free PMC article.

• Hyaluronic acid based materials for intestine tissue engineering: a morphological and biochemical study of cell-material interaction.

  Esposito A, Mezzogiorno A, Sannino A, De Rosa A, Menditti D, Esposito V, Ambrosio L. Esposito A, et al. J Mater Sci Mater Med. 2006 Dec;17(12):1365-72. doi: 10.1007/s10856-006-0612-x. J Mater Sci Mater Med. 2006. PMID: 17143769

• Distraction Enterogenesis in Rats: A Novel Approach for the Treatment of Short Bowel Syndrome.

  O'Quin C, Clayton SD, Trosclair L, Meyer H, Dao NH, Minagar A, White L, Welch V, Solitro G, Alexander JS, Sorrells D. O'Quin C, et al. Pathophysiology. 2024 Jul 30;31(3):388-397. doi: 10.3390/pathophysiology31030029. Pathophysiology. 2024. PMID: 39189165 Free PMC article.

• Peptide absorption after massive proximal small bowel resection: mechanisms of ileal adaptation.

  Qandeel HG, Alonso F, Hernandez DJ, Madhavan S, Duenes JA, Zheng Y, Sarr MG. Qandeel HG, et al. J Gastrointest Surg. 2011 Sep;15(9):1537-47. doi: 10.1007/s11605-011-1581-z. Epub 2011 Jun 7. J Gastrointest Surg. 2011. PMID: 21647767 Free PMC article.

Publication types

MeSH terms