Theta oscillations in the hippocampus - PubMed

Affiliations

• PMID: 11832222
• DOI: 10.1016/s0896-6273(02)00586-x

Free article

Review

Theta oscillations in the hippocampus

György Buzsáki. Neuron. 2002.

Free article

Abstract

Theta oscillations represent the "on-line" state of the hippocampus. The extracellular currents underlying theta waves are generated mainly by the entorhinal input, CA3 (Schaffer) collaterals, and voltage-dependent Ca(2+) currents in pyramidal cell dendrites. The rhythm is believed to be critical for temporal coding/decoding of active neuronal ensembles and the modification of synaptic weights. Nevertheless, numerous critical issues regarding both the generation of theta oscillations and their functional significance remain challenges for future research.

Similar articles

• Long-term plasticity is proportional to theta-activity.

  Tsanov M, Manahan-Vaughan D. Tsanov M, et al. PLoS One. 2009 Jun 9;4(6):e5850. doi: 10.1371/journal.pone.0005850. PLoS One. 2009. PMID: 19513114 Free PMC article.

• Hippocampus and Entorhinal Cortex Recruit Cholinergic and NMDA Receptors Separately to Generate Hippocampal Theta Oscillations.

  Gu Z, Alexander GM, Dudek SM, Yakel JL. Gu Z, et al. Cell Rep. 2017 Dec 19;21(12):3585-3595. doi: 10.1016/j.celrep.2017.11.080. Cell Rep. 2017. PMID: 29262336 Free PMC article.

• Nicotine induction of theta frequency oscillations in rodent hippocampus in vitro.

  Lu CB, Henderson Z. Lu CB, et al. Neuroscience. 2010 Mar 10;166(1):84-93. doi: 10.1016/j.neuroscience.2009.11.072. Epub 2009 Dec 23. Neuroscience. 2010. PMID: 20004706

Cited by

• Phase coding by grid cells in unconstrained environments: two-dimensional phase precession.

  Climer JR, Newman EL, Hasselmo ME. Climer JR, et al. Eur J Neurosci. 2013 Aug;38(4):2526-41. doi: 10.1111/ejn.12256. Epub 2013 May 29. Eur J Neurosci. 2013. PMID: 23718553 Free PMC article.

• Theta and beta oscillatory dynamics in the dentate gyrus reveal a shift in network processing state during cue encounters.

  Rangel LM, Chiba AA, Quinn LK. Rangel LM, et al. Front Syst Neurosci. 2015 Jul 1;9:96. doi: 10.3389/fnsys.2015.00096. eCollection 2015. Front Syst Neurosci. 2015. PMID: 26190979 Free PMC article.

• Imagination as a fundamental function of the hippocampus.

  Comrie AE, Frank LM, Kay K. Comrie AE, et al. Philos Trans R Soc Lond B Biol Sci. 2022 Dec 19;377(1866):20210336. doi: 10.1098/rstb.2021.0336. Epub 2022 Oct 31. Philos Trans R Soc Lond B Biol Sci. 2022. PMID: 36314152 Free PMC article. Review.

• Oscillatory activity during maintenance of spatial and temporal information in working memory.

  Roberts BM, Hsieh LT, Ranganath C. Roberts BM, et al. Neuropsychologia. 2013 Jan;51(2):349-57. doi: 10.1016/j.neuropsychologia.2012.10.009. Epub 2012 Oct 16. Neuropsychologia. 2013. PMID: 23084981 Free PMC article.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Elsevier Science

• Other Literature Sources

  • The Lens - Patent Citations Database

• Miscellaneous

  • NCI CPTAC Assay Portal