Checkpoint signalling: focusing on 53BP1 - PubMed

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Checkpoint signalling: focusing on 53BP1

Robert T Abraham. Nat Cell Biol. 2002 Dec.

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• 53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer.

  DiTullio RA Jr, Mochan TA, Venere M, Bartkova J, Sehested M, Bartek J, Halazonetis TD. DiTullio RA Jr, et al. Nat Cell Biol. 2002 Dec;4(12):998-1002. doi: 10.1038/ncb892. Nat Cell Biol. 2002. PMID: 12447382

• DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.

  Fernandez-Capetillo O, Chen HT, Celeste A, Ward I, Romanienko PJ, Morales JC, Naka K, Xia Z, Camerini-Otero RD, Motoyama N, Carpenter PB, Bonner WM, Chen J, Nussenzweig A. Fernandez-Capetillo O, et al. Nat Cell Biol. 2002 Dec;4(12):993-7. doi: 10.1038/ncb884. Nat Cell Biol. 2002. PMID: 12447390

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