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The PredictProtein server - PubMed

️Wed Jan 01 2003

The PredictProtein server

Burkhard Rost et al. Nucleic Acids Res. 2003.

Abstract

PredictProtein (PP, http://cubic.bioc.columbia.edu/pp/) is an internet service for sequence analysis and the prediction of aspects of protein structure and function. Users submit protein sequence or alignments; the server returns a multiple sequence alignment, PROSITE sequence motifs, low-complexity regions (SEG), ProDom domain assignments, nuclear localisation signals, regions lacking regular structure and predictions of secondary structure, solvent accessibility, globular regions, transmembrane helices, coiled-coil regions, structural switch regions and disulfide-bonds. Upon request, fold recognition by prediction-based threading is available. For all services, users can submit their query either by electronic mail or interactively from World Wide Web.

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Figures

**Figure 1**
Data flow for PredictProtein (PP). Users query PP with their protein and receive a single file with results from database comparisons and prediction methods. Users can query PP through email and web interfaces.

**Figure 2**
Usage of PredictProtein. The number of requests to PP continues to rise (A); over one million requests came from 95 countries. Almost half of all the requests originated from North America (B).

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The PredictProtein server - PubMed