pubmed.ncbi.nlm.nih.gov

Coexistence of erythromelalgia and Raynaud's phenomenon - PubMed

Review

Coexistence of erythromelalgia and Raynaud's phenomenon

Alexander L Berlin et al. J Am Acad Dermatol. 2004 Mar.

Abstract

Erythromelalgia is characterized by spontaneous recurrent episodes of redness, heat, and pain of the extremities that can be triggered or worsened by heat. Raynaud's phenomenon occurs in response to cold exposure and presents as pallor of the fingers or toes, often followed by cyanosis and rubor. Although the 2 conditions may appear to be opposites in symptomatology and clinical presentation, there are very rare reports of their coexistence. A case of coexistent erythromelalgia and Raynaud's phenomenon is presented. The pathophysiology is reviewed to elucidate a common mechanism underlying some cases of the 2 seemingly opposite conditions. A review of the literature indicates that causative and pathophysiologic similarities between the 2 conditions may exist in some cases. Rare reports of coexistence of the 2 disease processes further strengthen such research findings.

PubMed Disclaimer

Similar articles

  • [Methylphenidate and secondary Raynaud's phenomenon].

    Iglesias Otero M, Portela Romero M, Bugarín González R, Ventura Victoria MA. Iglesias Otero M, et al. Semergen. 2013 Sep;39(6):330-4. doi: 10.1016/j.semerg.2012.07.011. Epub 2012 Nov 4. Semergen. 2013. PMID: 24034762 Spanish.

  • Coexistence of erythromelalgia and Raynaud's phenomenon.

    Chatterjee S. Chatterjee S. Joint Bone Spine. 2023 Jul;90(4):105561. doi: 10.1016/j.jbspin.2023.105561. Epub 2023 Mar 17. Joint Bone Spine. 2023. PMID: 36933784 No abstract available.

  • [Cyanotic Raynaud's phenomenon: a peculiar symptomatologic entity].

    Andreozzi GM, Signorelli S, Monaco S, Martini R, Ferrara M, Palazzo V. Andreozzi GM, et al. J Mal Vasc. 1988;13(2):179. J Mal Vasc. 1988. PMID: 3397677 French. No abstract available.

  • Raynaud's phenomenon: pathogenesis and management.

    Bakst R, Merola JF, Franks AG Jr, Sanchez M. Bakst R, et al. J Am Acad Dermatol. 2008 Oct;59(4):633-53. doi: 10.1016/j.jaad.2008.06.004. Epub 2008 Jul 24. J Am Acad Dermatol. 2008. PMID: 18656283 Review.

  • Treatment of Raynaud's phenomenon.

    García-Carrasco M, Jiménez-Hernández M, Escárcega RO, Mendoza-Pinto C, Pardo-Santos R, Levy R, Maldonado CG, Chávez GP, Cervera R. García-Carrasco M, et al. Autoimmun Rev. 2008 Oct;8(1):62-8. doi: 10.1016/j.autrev.2008.07.002. Epub 2008 Aug 8. Autoimmun Rev. 2008. PMID: 18692160 Review.

Cited by

Publication types

MeSH terms