Treatment of childhood migraine attacks with oral zolmitriptan and ibuprofen - PubMed

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• PMID: 16775229
• DOI: 10.1212/01.wnl.0000231138.18629.d5

Randomized Controlled Trial

Treatment of childhood migraine attacks with oral zolmitriptan and ibuprofen

S Evers et al. Neurology. 2006.

Abstract

The authors conducted a double-blind, placebo-controlled, crossover study to investigate the efficacy of oral zolmitriptan in the treatment of migraine in children and adolescents. Patients (n = 32) received placebo, zolmitriptan 2.5 mg, and ibuprofen 200 to 400 mg to treat three consecutive migraine attacks. Pain relief rates after 2 hours were 28% for placebo, 62% for zolmitriptan, and 69% for ibuprofen (p < 0.05). Both drugs are well tolerated with only mild side effects.

Comment in

• Treatment of childhood migraine attacks with oral zolmitriptan and ibuprofen.

  Kornblau DH. Kornblau DH. Neurology. 2007 Apr 24;68(17):1441. doi: 10.1212/01.wnl.0000265417.92959.26. Neurology. 2007. PMID: 17452599 No abstract available.

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