Biotechnological production of spider-silk proteins enables new applications - PubMed
- ️Mon Jan 01 2007
Review
. 2007 Apr 10;7(4):401-9.
doi: 10.1002/mabi.200600255.
Affiliations
- PMID: 17429812
- DOI: 10.1002/mabi.200600255
Review
Biotechnological production of spider-silk proteins enables new applications
Charlotte Vendrely et al. Macromol Biosci. 2007.
Abstract
The outstanding mechanical properties of spider silks have motivated many researchers to establish biotechnological production techniques which are necessary to provide sufficient amounts of silk proteins for industrial applications. Based on recent developments in genetic engineering, two strategies for the recombinant production of spider-silk proteins have been established which are discussed in detail. Further, protein-design strategies are described, enabling the combination of silk properties with additional biological, chemical, or technical features. We highlight the potential of engineered and recombinantly-produced spider-silk proteins to provide the basis for a new generation of biomaterials.
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