Phase-locked responses to pure tones in the auditory thalamus - PubMed

Affiliations

• PMID: 17699690
• DOI: 10.1152/jn.00697.2007

Free article

Phase-locked responses to pure tones in the auditory thalamus

Mark N Wallace et al. J Neurophysiol. 2007 Oct.

Free article

Abstract

Accurate temporal coding of low-frequency tones by spikes that are locked to a particular phase of the sine wave (phase-locking), occurs among certain groups of neurons at various processing levels in the brain. Phase-locked responses have previously been studied in the inferior colliculus and neocortex of the guinea pig and we now describe the responses in the auditory thalamus. Recordings were made from 241 single units, 32 (13%) of which showed phase-locked responses. Units with phase-locked responses were mainly (82%) located in the ventral division of the medial geniculate body (MGB), and also the medial division (18%), but were not found in the dorsal or shell divisions. The upper limiting frequency of phase-locking varied greatly between units (60-1,100 Hz) and between anatomical divisions. The upper limit in the ventral division was 520 Hz and in the medial was 1,100 Hz. The range of steady-state delays calculated from phase plots also varied: ventral division, 8.6-14 ms (mean 11.1 ms; SD 1.56); medial division, 7.5-11 ms (mean 9.3 ms; SD 1.5). Taken together, these measurements are consistent with the medial division receiving a phase-locked input directly from the brain stem, without an obligatory relay in the inferior colliculus. Cells in both the ventral and medial divisions of the MGB showed a response that phase-locked to the fundamental frequency of a guinea pig purr and may be involved in analyzing communication calls.

Similar articles

• Phase-locked responses to pure tones in the inferior colliculus.

  Liu LF, Palmer AR, Wallace MN. Liu LF, et al. J Neurophysiol. 2006 Mar;95(3):1926-35. doi: 10.1152/jn.00497.2005. Epub 2005 Dec 7. J Neurophysiol. 2006. PMID: 16339005

• Evidence for a direct, short latency projection from the dorsal cochlear nucleus to the auditory thalamus in the guinea pig.

  Anderson LA, Malmierca MS, Wallace MN, Palmer AR. Anderson LA, et al. Eur J Neurosci. 2006 Jul;24(2):491-8. doi: 10.1111/j.1460-9568.2006.04930.x. Epub 2006 Jul 12. Eur J Neurosci. 2006. PMID: 16836634

• Phase-locked responses to pure tones in the primary auditory cortex.

  Wallace MN, Shackleton TM, Palmer AR. Wallace MN, et al. Hear Res. 2002 Oct;172(1-2):160-71. doi: 10.1016/s0378-5955(02)00580-4. Hear Res. 2002. PMID: 12361879

• Coding of communication calls in the subcortical and cortical structures of the auditory system.

  Suta D, Popelár J, Syka J. Suta D, et al. Physiol Res. 2008;57 Suppl 3:S149-S159. doi: 10.33549/physiolres.931608. Epub 2008 May 13. Physiol Res. 2008. PMID: 18481905 Review.

• Corticofugal modulation of the auditory thalamus.

  He J. He J. Exp Brain Res. 2003 Dec;153(4):579-90. doi: 10.1007/s00221-003-1680-5. Epub 2003 Oct 22. Exp Brain Res. 2003. PMID: 14574430 Review.

Cited by

• A Role for Auditory Corticothalamic Feedback in the Perception of Complex Sounds.

  Homma NY, Happel MFK, Nodal FR, Ohl FW, King AJ, Bajo VM. Homma NY, et al. J Neurosci. 2017 Jun 21;37(25):6149-6161. doi: 10.1523/JNEUROSCI.0397-17.2017. Epub 2017 May 30. J Neurosci. 2017. PMID: 28559384 Free PMC article.

• The organization and physiology of the auditory thalamus and its role in processing acoustic features important for speech perception.

  Bartlett EL. Bartlett EL. Brain Lang. 2013 Jul;126(1):29-48. doi: 10.1016/j.bandl.2013.03.003. Brain Lang. 2013. PMID: 23725661 Free PMC article. Review.

• Correlation of neural response properties with auditory thalamus subdivisions in the awake marmoset.

  Bartlett EL, Wang X. Bartlett EL, et al. J Neurophysiol. 2011 Jun;105(6):2647-67. doi: 10.1152/jn.00238.2010. Epub 2011 Mar 16. J Neurophysiol. 2011. PMID: 21411564 Free PMC article.

• Robustness to Noise in the Auditory System: A Distributed and Predictable Property.

  Souffi S, Lorenzi C, Huetz C, Edeline JM. Souffi S, et al. eNeuro. 2021 Mar 18;8(2):ENEURO.0043-21.2021. doi: 10.1523/ENEURO.0043-21.2021. Print 2021 Mar-Apr. eNeuro. 2021. PMID: 33632813 Free PMC article.

• Noise-Sensitive But More Precise Subcortical Representations Coexist with Robust Cortical Encoding of Natural Vocalizations.

  Souffi S, Lorenzi C, Varnet L, Huetz C, Edeline JM. Souffi S, et al. J Neurosci. 2020 Jul 1;40(27):5228-5246. doi: 10.1523/JNEUROSCI.2731-19.2020. Epub 2020 May 22. J Neurosci. 2020. PMID: 32444386 Free PMC article.

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Atypon