A second-generation combined linkage physical map of the human genome - PubMed
. 2007 Dec;17(12):1783-6.
doi: 10.1101/gr.7156307. Epub 2007 Nov 7.
Fang Chen, Wenwei Chen, Francisco M De La Vega, Mark Hansen, Chunsheng He, Fiona C L Hyland, Giulia C Kennedy, Xiangyang Kong, Sarah S Murray, Janet S Ziegle, William C L Stewart, Steven Buyske
Affiliations
- PMID: 17989245
- PMCID: PMC2099587
- DOI: 10.1101/gr.7156307
A second-generation combined linkage physical map of the human genome
Tara C Matise et al. Genome Res. 2007 Dec.
Abstract
We have completed a second-generation linkage map that incorporates sequence-based positional information. This new map, the Rutgers Map v.2, includes 28,121 polymorphic markers with physical positions corroborated by recombination-based data. Sex-averaged and sex-specific linkage map distances, along with confidence intervals, have been estimated for all map intervals. In addition, a regression-based smoothed map is provided that facilitates interpolation of positions of unmapped markers on this map. With nearly twice as many markers as our first-generation map, the Rutgers Map continues to be a unique and comprehensive resource for obtaining genetic map information for large sets of polymorphic markers.
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