Understanding the risk of using medications for attention deficit hyperactivity disorder with respect to physical growth and cardiovascular function - PubMed
Review
Understanding the risk of using medications for attention deficit hyperactivity disorder with respect to physical growth and cardiovascular function
Benedetto Vitiello. Child Adolesc Psychiatr Clin N Am. 2008 Apr.
Abstract
The effects of stimulant medications and atomoxetine on physical growth and on cardiovascular function are reviewed in light of the most recent data, with attention to clinical implications and research needs. Although these medications have a favorable benefit/risk profile and do not induce clinically significant changes in growth or cardiovascular function in the majority of cases, careful patient monitoring is needed to identify individuals at risk for negative outcomes. More research is needed to elucidate the mechanism of growth suppression to estimate better the risk for rare but life-threatening events and test the effectiveness of monitoring procedures.
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References
-
- Greenhill LL, Swanson JM, Vitiello B, et al. Impairment and deportment responses to different methylphenidate doses in children with ADHD: the MTA titration trial. J Am Acad Child Adolesc Psychiatry. 2001;40:180–187. - PubMed
-
- Wigal T, Greenhill LL, Chuang S, et al. Safety and tolerability of methylphenidate in preschool children with ADHD. J Am Acad Child Adolesc Psychiatry. 2006;45:1294–1303. - PubMed
-
- Efron D, Jarman F, Barker M. Side effects of methylphenidate and dexamphetamine in children with attention deficit hyperactivity disorder: a double-blind, crossover trial. Pediatrics. 1997;100:662–666. - PubMed
-
- Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. A randomized controlled crossover trial of methylphenidate in pervasive developmental disorders with hyperactivity. Arch Gen Psychiatry. 2005;62:1266–1274. - PubMed
-
- Zuvekas SH, Vitiello B, Norquist NS. Recent Trends in Stimulant Medication Use among U.S. Children. Am J Psychiatry. 2006;163:579–585. - PubMed
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