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Global metabolic responses of mice to Trypanosoma brucei brucei infection - PubMed

  • ️Tue Jan 01 2008

Typical 600 MHz 1H NMR spectra of urine obtained from a mouse at preinfection (A), at 14 days postinfection (B), and at 28 days postinfection (C). The spectra in the aromatic region (δ 6.5–8.0) were magnified 4 times compared with the region δ 2.3–4.3, whereas the region δ 0.7–2.3 was magnified twice. Key: 1, 2-oxoisocaproate; 2, 3-methyl-2-oxovalerate; 3, 3-carboxy-2-methyl-3-oxopropanamine; 4, 2-oxoisovalerate; 5,

d

-3-hydroxybutyrate; 6, acetate; 7, succinate; 8, β-alanine; 9, 2-oxoglutarate; 10, trimethylamine; 11, citrate; 12, dimethylamine; 13, creatine; 14, trimethylamine-N-oxide; 15, malonate; 16, taurine; 17, glycine; 18, phenylacetylglycine; 19, tryptophan; 20, hippurate; 21, lactate; 22, 4-hydroxyphenylacetic acid; 23, alanine, 24, methylcrotonic acid.